Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Cogstate's cognition test to play key role in A4 trial for Alzheimer’s disease

Cognition testing technology developed by Cogstate will be used to track the neurological health of elderly people involved in the multinational Phase III clinical trial of a promising new Alzheimer’s disease (AD) drug.

26 Mar 2014

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Researchers from Boston University School of Medicine have found that the diabetic drug, pramlintide, reduces amyloid-beta peptides, a major component of Alzheimer's disease (AD) in the brain and improves learning and memory in two experimental AD models.

25 Mar 2014

New treatment could halt progression of dementia

Researchers at the University of Texas Medical Branch at Galveston have discovered a way to potentially halt the progression of dementia caused by accumulation of a protein known as tau.

21 Mar 2014

People who develop diabetes in middle age are more likely to have brain cell loss in old age

People who develop diabetes and high blood pressure in middle age are more likely to have brain cell loss and other damage to the brain, as well as problems with memory and thinking skills, than people who never have diabetes or high blood pressure or who develop it in old age, according to a new study published in the March 19, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

20 Mar 2014

PredictND project aims at validating new procedures for early diagnosis of memory disorders

The PredictND project, started by European research organisations, aims at developing and validating new procedures for the earlier diagnosis of memory disorders and for detecting individuals at high risk of developing memory disorders. Millions of Europeans who are at risk for experiencing any kind of memory loss would benefit from such a solution.

19 Mar 2014

Computer analysis of various subtypes of asthma could eventually lead to improved therapy, says study

So many variables can contribute to shortness of breath that no person can keep them all straight. But a computer program, capable of tracking more than 100 clinical variables for almost 400 people, has shown it can identify various subtypes of asthma, which perhaps could lead to targeted, more effective treatments.

19 Mar 2014

Neuralstem announces results from Phase I trial using NSI-566 spinal cord stem cells in treatment of ALS

Neuralstem, Inc. (NYSE MKT: CUR) announced that the final results from the Phase I safety trial using NSI-566 spinal cord stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) were published in the peer-reviewed journal, "Annals of Neurology".

18 Mar 2014

Scientists develop new mechanism that helps decode amyloid plaque formation in brains of Alzheimer's patients

University of Michigan researchers have learned how to fix a cellular structure called the Golgi that mysteriously becomes fragmented in all Alzheimer's patients and appears to be a major cause of the disease.

18 Mar 2014

Eye abnormalities may help reveal features of early-stage Alzheimer's disease, says study

Investigators at the Cedars-Sinai Regenerative Medicine Institute have discovered eye abnormalities that may help reveal features of early-stage Alzheimer's disease. Using a novel laboratory rat model of Alzheimer's disease and high-resolution imaging techniques, researchers correlated variations of the eye structure, to identify initial indicators of the disease.

18 Mar 2014

Findings support development of cysteine protease inhibitors as new drug target for AD

A team of scientists from the University of California, San Diego School of Medicine, the Medical University of South Carolina and San Diego-based American Life Science Pharmaceuticals, Inc., report that cathepsin B gene knockout or its reduction by an enzyme inhibitor blocks creation of key neurotoxic pGlu-Aβ peptides linked to Alzheimer's disease (AD). Moreover, the candidate inhibitor drug has been shown to be safe in humans.

18 Mar 2014

Viewpoints: The lesson from Florida's special election; hospital deaths; costs of treating hep C

But in recent months, the political landscape has grown bleaker [for Democrats] .... The question, of course, is why so many Republicans turned out [in the Florida special election last week] and why so few Democrats did. The answer among strategists on both sides was: Obamacare. But not in the sense that the healthcare law is so unpopular that Democrats are doomed; in fact, as more people sign up for health coverage, polls suggest that Obamacare is a little less toxic now than it was last fall. Instead, the problem is that a high-decibel debate over Obamacare has the effect of prompting conservatives to come out and vote, but not liberals (Doyle McManus, 3/16).

18 Mar 2014

CorTechs secures new Series B financing

Medical software developer CorTechs Labs, Inc. is pleased to announce it has secured new Series B financing to support the company's rapid growth. The round was led by Genting Berhad via its indirect wholly-owned subsidiary, Dragasac Limited, a company incorporated in the Isle of Man.

18 Mar 2014

People who experience chronic sleep disturbance could face earlier onset of dementia, Alzheimer's

People who experience chronic sleep disturbance—either through their work, insomnia or other reasons—could face an earlier onset of dementia and Alzheimer's, according to a new pre-clinical study by researchers at Temple University.

18 Mar 2014

Scientists uncover how inflammation and lack of oxygen cause brain damage

Scientists have uncovered how inflammation and lack of oxygen conspire to cause brain damage in conditions such as stroke and Alzheimer's disease.

14 Mar 2014

Viewpoints: The impact of Florida's special election; drug testing for doctors; the toll from Alzheimer's

A rule of electoral politics is that when a Democratic wave is building, the media broadcast it like a foregone conclusion. When a Republican wave is building, Beltway pundits are the last to admit it. After Tuesday's GOP win in a Florida special House election, even the press corps now agrees that Republicans are poised for major gains in November, assuming the GOP has the wit to exploit it (3/12).

14 Mar 2014

Researcher detects higher rate of seizures among children with autism who were fed soy formula

A University of Wisconsin-Madison researcher has detected a higher rate of seizures among children with autism who were fed infant formula containing soy protein rather than milk protein.

14 Mar 2014

University of Chicago/ MBL announce first two recipients of Frank R. Lillie Research Innovation Awards

The University of Chicago and the Marine Biological Laboratory (MBL) today announced the first two recipients of the Frank R. Lillie Research Innovation Awards.

14 Mar 2014

People with prehypertension more likely to develop stroke

Anyone with blood pressure that's higher than the optimal 120/80 mmHg may be more likely to have a stroke, according to a new meta-analysis published in the March 12, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Mar 2014

Three innovative tools to detect, test and initiate personalized drug treatment for seizures

A team of researchers from the National Institutes of Health, Emory University and Cedars-Sinai - specialists in identifying and treating very rare diseases - used three innovative tools to detect a previously unknown gene mutation, test potential therapies in the lab, and initiate personalized drug treatment for a boy with a lifelong history of uncontrollable seizures that caused significant impact on his cognitive and social development.

12 Mar 2014

Researchers find that brain cell regeneration may alleviate symptoms of Alzheimer's disease

Alzheimer's disease is the most widespread degenerative neurological disorder in the world. Over five million Americans live with it, and one in three senior citizens will die with the disease or a similar form of dementia. While memory loss is a common symptom of Alzheimer's, other behavioral manifestations - depression, loss of inhibition, delusions, agitation, anxiety, and aggression - can be even more challenging for victims and their families to live with.

12 Mar 2014

Alzheimer's Disease News and Research

Further Reading

Cogstate's cognition test to play key role in A4 trial for Alzheimer’s disease

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

New treatment could halt progression of dementia

People who develop diabetes in middle age are more likely to have brain cell loss in old age

PredictND project aims at validating new procedures for early diagnosis of memory disorders

Computer analysis of various subtypes of asthma could eventually lead to improved therapy, says study

Neuralstem announces results from Phase I trial using NSI-566 spinal cord stem cells in treatment of ALS

Scientists develop new mechanism that helps decode amyloid plaque formation in brains of Alzheimer's patients

Eye abnormalities may help reveal features of early-stage Alzheimer's disease, says study

Findings support development of cysteine protease inhibitors as new drug target for AD

Viewpoints: The lesson from Florida's special election; hospital deaths; costs of treating hep C

CorTechs secures new Series B financing

People who experience chronic sleep disturbance could face earlier onset of dementia, Alzheimer's

Scientists uncover how inflammation and lack of oxygen cause brain damage

Viewpoints: The impact of Florida's special election; drug testing for doctors; the toll from Alzheimer's

Researcher detects higher rate of seizures among children with autism who were fed soy formula

University of Chicago/ MBL announce first two recipients of Frank R. Lillie Research Innovation Awards

People with prehypertension more likely to develop stroke

Three innovative tools to detect, test and initiate personalized drug treatment for seizures

Researchers find that brain cell regeneration may alleviate symptoms of Alzheimer's disease

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