Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

SimuCase avatars allow graduate students to evaluate speech-language disorders

A new commercial venture, using technology developed at Case Western Reserve University's College of Arts and Sciences and Case School of Engineering, has made available avatars-virtual patients-to train speech-language pathologists.

19 Jun 2013

Signaling pathway correlates with EGFR status and poor survival in breast cancer patients

Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point.

19 Jun 2013

Researchers discover a rational source of pain in skin of patients with fibromyalgia

Fibromyalgia, a painful condition affecting approximately 10 million people in the U.S., is not imaginary after all, as some doctors have believed. A discovery, published this month in PAIN MEDICINE (the journal of the American Academy of Pain Medicine), clearly now demonstrates that fibromyalgia may have a rational biological basis located in the skin.

19 Jun 2013

UCLA surgeons perform minimally invasive procedure to remove large polyps and keep colon intact

Millions of people each year have polyps successfully removed during colonoscopies. But when a suspicious polyp is bigger than a marble or in a hard-to-reach location, patients are referred for surgery to remove a portion of their colon - even if doctors aren't sure whether the polyp is cancerous or not.

18 Jun 2013

Blocking B1R receptor activity in brains of Alzheimer's mice recovers memory and cerebrovascular function

A new study shows that memory pathology in older mice with Alzheimer's disease can be reversed with treatment. The study by researchers from the Montreal Neurological Institute and Hospital - The Neuro, at McGill University and at Universit- de Montr-al found that blocking the activity of a specific receptor in the brain of mice with advanced Alzheimer's disease (AD) recovers memory and cerebrovascular function.

18 Jun 2013

Genomic instability in new molecular pathway may predict worse outcomes in breast cancer patients

A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

18 Jun 2013

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Harvard Stem Cell Institute researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its activity.

18 Jun 2013

Medical experts spot cancerous abnormalities on medical images in a single glance

Have you ever thought that you knew something about the world in the blink of an eye? This restaurant is not the right place for dinner. That person could be The One. It turns out that radiologists can do this with mammograms, the x-ray images used for breast cancer screening. Cytologists, who screen micrographic images of cervical cells to detect cervical cancer, have a similar ability. A new study, published in Springer's journal Psychonomic Bulletin & Review, takes a closer look at the skill these specialists have.

18 Jun 2013

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Although a family history of Alzheimer's disease is a primary risk factor for the devastating neurological disorder, mutations in only three genes - the amyloid precursor protein and presenilins 1 and 2 - have been established as causative for inherited, early-onset Alzheimer's, accounting for about half of such cases.

18 Jun 2013

Final results of PUFs clinical study of Covidien's Pipeline device published in June issue of Radiology

Covidien, a leading global provider of healthcare products, today announced that the final results of the PUFs (Pipeline for Uncoilable or Failed Aneurysms) clinical study of its Pipeline embolization device have been published in the June issue of Radiology.

17 Jun 2013

Penn Medicine to participate in PathCentral Pathology Network

PathCentral, a technology-enabled company dedicated to the success of the international pathology community, announced today that Penn Medicine will participate in the PathCentral Pathology Network, the specialty's most comprehensive online information exchange and digital consultation forum.

17 Jun 2013

Researchers uncover DNA damage checkpoint used by cells to monitor oxidatively damaged DNA

In current health lore, antioxidants are all the rage, as "everybody knows" that reducing the amount of "reactive oxygen species" -- cell-damaging molecules that are byproducts of cellular metabolism -- is critical to staying healthy. What everyone doesn't know is that our bodies already have a complex set of processes built into our cells that handle these harmful byproducts of living and repair the damage they cause.

15 Jun 2013

Hospitalized patients do not receive blood thinners to prevent blood clots, researchers report

Researchers at Johns Hopkins report that hospitalized patients do not receive more than one in 10 doses of doctor-ordered blood thinners prescribed to prevent potentially lethal or disabling blood clots, a decision they say may be fueled by misguided concern by patients and their caregivers.

15 Jun 2013

Researchers are one step closer to treating type 1 diabetes

Researchers at Washington University School of Medicine in St. Louis have identified a way to trigger reproduction in the laboratory of clusters of human cells that make insulin, potentially removing a significant obstacle to transplanting the cells as a treatment for patients with type 1 diabetes.

14 Jun 2013

Researchers at Albert Einstein College of Medicine convene one-day conference on Jewish genetics

Today, researchers at Albert Einstein College of Medicine of Yeshiva University convened a one-day conference on Jewish genetics designed to encourage collaboration and advance the field of research.

14 Jun 2013

Supreme Court invalidates patents held by Myriad Genetics

The College of American Pathologists applauds today's unanimous Supreme Court decision invalidating the patents held by Myriad Genetics on the BRCA1 and BRCA2 genes. It is a victory for patients and for science.

14 Jun 2013

CSHL scientists solve the mystery of why some infants born with grave syndrome

By identifying a protein that acts as a genetic modifier, scientists at Cold Spring Harbor Laboratory have solved the mystery of why some infants are born with a grave syndrome consisting of cleft palate and major deformities of the skin and limbs, while other infants bearing the same predisposing genetic mutation bear little or no sign of the illness, called EEC.

14 Jun 2013

SV Bio receives CLIA certification for in silico diagnostics laboratory

Silicon Valley Biosystems today announced that it has received Clinical Laboratory Improvement Amendment certification from the California Department of Public Health for its in silico diagnostics laboratory.

13 Jun 2013

Study unravels cause of hearing loss in humans

A novel genetic mutation was first identified in 2010 as causing hearing loss in humans. Researchers have now discovered that this mutation induces malfunction of an inhibitor of an enzyme commonly found in our body that destroys proteins.

13 Jun 2013

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

Alzheimer's disease has been linked in many studies to amyloid plaque buildup in the brain, but new research is finding a common thread between amyloid burden and lower energy levels, or metabolism, of neurons in certain areas of the brain associated with Alzheimer's disease-even for people with no sign of cognitive decline.

12 Jun 2013

Pathology News and Research

Further Reading

SimuCase avatars allow graduate students to evaluate speech-language disorders

Signaling pathway correlates with EGFR status and poor survival in breast cancer patients

Researchers discover a rational source of pain in skin of patients with fibromyalgia

UCLA surgeons perform minimally invasive procedure to remove large polyps and keep colon intact

Blocking B1R receptor activity in brains of Alzheimer's mice recovers memory and cerebrovascular function

Genomic instability in new molecular pathway may predict worse outcomes in breast cancer patients

Targeting SALL4 protein with druglike molecules could halt tumor growth, say researchers

Medical experts spot cancerous abnormalities on medical images in a single glance

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Final results of PUFs clinical study of Covidien's Pipeline device published in June issue of Radiology

Penn Medicine to participate in PathCentral Pathology Network

Researchers uncover DNA damage checkpoint used by cells to monitor oxidatively damaged DNA

Hospitalized patients do not receive blood thinners to prevent blood clots, researchers report

Researchers are one step closer to treating type 1 diabetes

Researchers at Albert Einstein College of Medicine convene one-day conference on Jewish genetics

Supreme Court invalidates patents held by Myriad Genetics

CSHL scientists solve the mystery of why some infants born with grave syndrome

SV Bio receives CLIA certification for in silico diagnostics laboratory

Study unravels cause of hearing loss in humans

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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