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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Proteomic and transcriptomic profiling provide a full picture of aging process in the kidneys

Studying protein changes in the kidneys as we age, as well as the transcription of genes into proteins, helps provide a full picture of the age-related processes that take place in these organs, says a study in mice published today in eLife.

4 May 2021

Unique system detects small changes in DNA structures

Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they've been extremely difficult to detect -- until now.

4 May 2021

Four-part small-molecule cocktail can prevent cellular stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

Rucaparib drug is effective in treating certain types of ovarian cancers, shows study

A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build up a resistance to chemotherapy.

4 May 2021

Developmental abnormalities are controlled by genetics of the fetus and placenta

Yale researchers have shown that developmental abnormalities, including those that lead to pregnancy loss and autism, are controlled by the genetics of the fetus and placenta -- and not the mother's intrauterine environment.

4 May 2021

Ravi Sheth receives 2020 Hertz thesis prize for transforming microbial research

Hertz Fellow Ravi Sheth says his lab in the Brooklyn Navy Yard is "like a Willy Wonka factory of microbes" geared toward improving the taste and safety of food and beverages.

4 May 2021

Low doses of ionizing radiation may be a promising therapy for people with Alzheimer’s disease

Individuals living with severe Alzheimer's disease showed remarkable improvements in behavior and cognition within days of receiving an innovative new treatment that delivered low doses of radiation, a recent Baycrest-Sunnybrook pilot study found.

3 May 2021

Designing effective multidrug-resistant-TB treatments based on DNA sequencing

Globally, tuberculosis is the most common bacterial infectious disease leading to death. The pathogen causing tuberculosis, Mycobacterium tuberculosis, has a number of peculiarities. One is that it is growing very slowly.

3 May 2021

Scientists investigate the role played by genes and environment in multiple substance use

Many drug addicts take not only one substance but rather several. Scientists at the Max Planck Institute of Experimental Medicine in Göttingen have investigated the role that genes and the environment play in the development of such multiple substance consumption or polytoxicomania.

3 May 2021

New gene therapy restores dystrophin protein in patients with Duchenne muscular dystrophy

UT Southwestern scientists successfully employed a new type of gene therapy to treat mice with Duchenne muscular dystrophy (DMD), uniquely utilizing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein that is missing in many DMD patients.

3 May 2021

Could CRISPR be used as a SARS-CoV-2 antiviral?

The potential of using this gene manipulation technology as a SARS-CoV-2 inhibitor or prophylactic is investigated in a review recently uploaded to the journal Experimental Biology and Medicine (April 25th, 2021) by Arnab Banerjee and colleagues.

2 May 2021

Correcting mutations in muscle stem cells using new gene-editing technology

A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders.

30 Apr 2021

UTHSC professor receives $2.87 million to study genetic alterations associated with Gulf War illness

The National Institute of Environmental Health Sciences has awarded Byron C. Jones, PhD, professor in the Department of Genetics, Genomics, and Informatics at the University of Tennessee Health Science Center, $2.87 million for his continuing study of genetic alterations associated with Gulf War illness among former military personnel.

30 Apr 2021

Researchers identify important factor in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease. These include the dendritic cells.

30 Apr 2021

Cell-free DNA tests can reduce the need for biopsies to detect rejection after heart transplant

A new study, presented today at the AATS 101st Annual Meeting, shows that non-invasive cell-free DNA tests can reduce the need for regular surveillance biopsies to detect early rejection in heart transplant patients. The study was the first of its kind to be performed on both adult and pediatric patients.

30 Apr 2021

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Study evaluates first tumor-uninformed ctDNA assay to detect residual cancer cells after treatment

After patients with cancer undergo surgery to remove a tumor and sometimes additional chemotherapy, tools are used to identify patients at highest risk of recurrence.

30 Apr 2021

Geisinger wins $3.6 million contract to study the role of genetic variation in cancer

The National Cancer Institute (NCI), part of the National Institutes of Health, has awarded a 5-year, $3.6 million contract to Geisinger to study the role of genetic variation in cancer.

29 Apr 2021

A new strain of common probiotic can potentially be more effective at protecting infant health

Researchers at the University of Helsinki have created a strain of the Lacticaseibacillus rhamnosus GG probiotic that is able to utilize both lactose and casein as well as reproduce in dairy products.

29 Apr 2021

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

Researchers at University of California San Diego School of Medicine have discovered one way in which SARS-CoV-2, the coronavirus that causes COVID-19, hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.

29 Apr 2021

DNA News and Research

Further Reading

Proteomic and transcriptomic profiling provide a full picture of aging process in the kidneys

Unique system detects small changes in DNA structures

Four-part small-molecule cocktail can prevent cellular stress

Rucaparib drug is effective in treating certain types of ovarian cancers, shows study

Developmental abnormalities are controlled by genetics of the fetus and placenta

Ravi Sheth receives 2020 Hertz thesis prize for transforming microbial research

Low doses of ionizing radiation may be a promising therapy for people with Alzheimer’s disease

Designing effective multidrug-resistant-TB treatments based on DNA sequencing

Scientists investigate the role played by genes and environment in multiple substance use

New gene therapy restores dystrophin protein in patients with Duchenne muscular dystrophy

Could CRISPR be used as a SARS-CoV-2 antiviral?

Correcting mutations in muscle stem cells using new gene-editing technology

UTHSC professor receives $2.87 million to study genetic alterations associated with Gulf War illness

Researchers identify important factor in the development of dendritic cells

Cell-free DNA tests can reduce the need for biopsies to detect rejection after heart transplant

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

Study evaluates first tumor-uninformed ctDNA assay to detect residual cancer cells after treatment

Geisinger wins $3.6 million contract to study the role of genetic variation in cancer

A new strain of common probiotic can potentially be more effective at protecting infant health

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

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