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Monoclonal antibody activity against SARS-CoV-2 Omicron variant

Scientists from Germany have recently pointed out that the third booster dose of mRNA-based COVID-19 vaccine is highly effective in neutralizing the omicron variant of SARS-CoV-2.

15 Dec 2021

Risk of Guillain-Barré syndrome decreases after COVID-19 vaccination

A new study suggests that low GBS incidence in vaccinated patients compared to non-vaccinated people should encourage the active propagation of vaccination against SARS-CoV-2.

15 Dec 2021

Structure of human receptor and Omicron variant

Researchers studied the complex structure of the receptor-binding domain of the omicron variant with the human host receptor angiotensin-converting enzyme 2.

15 Dec 2021

Thrombosis may increase mortality risk in hospitalized COVID-19 patients

A team of US-based scientists has recently explored various risk factors associated with the poor prognosis of coronavirus disease 2019 (COVID-19). They have identified thrombosis-related risk factors as a major predictor of in-hospital COVID-19 related mortality. The study is currently available on the medRxiv* preprint server while awaiting peer review.

14 Dec 2021

Study reveals molecular players involved in the onset of leukemia

A new study led by João T. Barata from Instituto de Medicina Molecular João Lobo Antunes (iMM, Portugal), and J. Andrés Yunes from Centro Infantil Boldrini (Brazil), published now in the scientific journal Nature Communications, shows that changes in a protein called IL-7R are sufficient to initiate a type of leukemia.

14 Dec 2021

Recycling tubular endosomes are associated with effective delivery of mRNA-based therapeutics, study finds

A recent study recently demonstrates the endosomal transport of nanoparticle-based formulations for the effective delivery of mRNA-based therapeutics.

14 Dec 2021

Childhood trauma may increase the risk of psychotic symptoms in young cannabis users

Childhood trauma may increase the chance of young people experiencing psychotic symptoms when using cannabis, University of Queensland research has found.

14 Dec 2021

England's Chief Medical Officer calls on the public to get booster vaccination

Chief Medical Officer for England Professor Chris Whitty will call on the public to get a booster vaccination, in a nationwide advertising campaign launching today (Tuesday 14 December) to further galvanize the booster program.

14 Dec 2021

Nanotrap particles can improve current sequencing workflows of SARS-CoV-2

New research uses an affinity-based magnetic hydrogel particle enrichment technology (Nanotrap particle enrichment technology) that can concentrate viral particles, leading to improved detection of many viral agents including SARS-CoV-2

14 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Trial in sub-Saharan Africa evaluates the efficacy of COVID-19 vaccine in people living with HIV

A highly anticipated clinical trial in eight sub-Saharan countries is the first to specifically evaluate the efficacy of a COVID-19 vaccine in people living with HIV, including those with poorly controlled infections.

13 Dec 2021

Omicron variant may strike double vaccinated

Largely, scientists are skeptical that the Omicron variant can infect vaccinated individuals. However, a new study published on the medRxiv* preprint server has conducted neutralization assays using an Omicron isolate obtained from patients residing in the United Kingdom.

13 Dec 2021

COVID-19 vaccines offer protection for multiple myeloma patients, but lesser than other cancer survivors

For patients with the blood cancer multiple myeloma, vaccination against COVID-19 provides some protection against coronavirus infection but to a far lower degree than the general population of cancer survivors, a new study by Dana-Farber Cancer Institute investigators shows.

13 Dec 2021

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

A new study published on the bioRxiv preprint server has hypothesized that T cell receptors (TCR) repertoire can measure the response to vaccines, as it would identify the TCR of clones that respond to the vaccination.

13 Dec 2021

$Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma$

Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma

The final results from a national phase 2 study including researchers from Yale Cancer Center show the drug tipifarnib increased survival rates for patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).

13 Dec 2021

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Efficacy News and Research

Monoclonal antibody activity against SARS-CoV-2 Omicron variant

Risk of Guillain-Barré syndrome decreases after COVID-19 vaccination

Structure of human receptor and Omicron variant

Thrombosis may increase mortality risk in hospitalized COVID-19 patients

Study reveals molecular players involved in the onset of leukemia

Recycling tubular endosomes are associated with effective delivery of mRNA-based therapeutics, study finds

Childhood trauma may increase the risk of psychotic symptoms in young cannabis users

England's Chief Medical Officer calls on the public to get booster vaccination

Nanotrap particles can improve current sequencing workflows of SARS-CoV-2

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Trial in sub-Saharan Africa evaluates the efficacy of COVID-19 vaccine in people living with HIV

Omicron variant may strike double vaccinated

COVID-19 vaccines offer protection for multiple myeloma patients, but lesser than other cancer survivors

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Characteristics of vaccine breakthroughs in fully vaccinated individuals in France with delta variant

Digital interventions may help meet the growing demand for psychological treatment

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

Novel assay using finger-prick samples provides COVID-19 vaccine efficacy data

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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