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Researchers discover how a sugar molecule can affect cancer cell response to chemoradiotherapy

Researchers at Georgetown University's Lombardi Comprehensive Cancer Center and colleagues who have been exploring the complexities of biochemical pathways involved in cancer development have found that a form of glucose, a type of sugar, is intricately linked to a pathway used to build DNA molecules.

12 Jun 2023

Study:Overactive inflammatory response could be at the root of many long COVID cases

An overactive inflammatory response could be at the root of many long COVID cases, according to a new study from the Allen Institute and Fred Hutchinson Cancer Center.

12 Jun 2023

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Review discusses the increasing importance of two-dimensional nanomaterials like graphene in neuroscience, highlighting their potential in nerve repair, creating brain-mimicking synaptic devices, and treating neurological disorders. It also considers the challenges and future prospects of these materials in this complex field.

11 Jun 2023

Using Src N-terminal regulatory element as potential oncotarget

A new research perspective was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "Targeting the Src N-terminal regulatory element in cancer."

9 Jun 2023

PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia

Humanigen, Inc.today extended previously reported results by presenting additional, statistically significant hematologic improvements and reductions in inflammatory markers from lenzilumab, its investigational drug, in a Phase 2/3 trial of treatment-naïve participants with chronic myelomonocytic leukemia and RAS-pathway mutations.

9 Jun 2023

New model can quickly screen large libraries of potential drug compounds

Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease.

9 Jun 2023

Innovative 'village in a dish' system can accelerate stem cell research

A powerful new stem cell technique has enabled large-scale studies of the relationship between human genetics and biology.

9 Jun 2023

SARS-CoV-2 hijacks body's metabolism to amplify COVID-19 severity

In a review article published in the journal Signal Transduction and Targeted Therapy, scientists have discussed host metabolic alteration triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its effect on disease severity.

9 Jun 2023

Exploring the viability of a new treatment for vascular dementia

Researchers from The University of Texas at El Paso's School of Pharmacy will explore the viability of a new treatment for vascular dementia, thanks to a $2.2 million grant from the National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS).

9 Jun 2023

Gut health boost: Functional foods and herbs show promise in tackling SARS-CoV-2 variants

Functional foods and natural herbs have the potential to enhance immune function and maintain gut microbiota diversity. This review explores their role in mitigating the impact of SARS-CoV-2 variants on gut health and overall well-being.

8 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

Study shows how blood makes the brain’s immune cells toxic

In patients with neurological diseases like Alzheimer's disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial functions become harmful to neurons, leading to cognitive dysfunction and motor impairment.

8 Jun 2023

First-in-class drug shows promise as a safe and effective treatment for cannabis use disorder

A first-in-class drug engineered to selectively inhibit the signaling pathway of the cannabinoid receptor shows promise as a safe and effective treatment for cannabis use disorder (CUD), a condition where a person is unable to control their cannabis use, even though it's causing problems in their lives.

8 Jun 2023

Global study provides high-quality data to improve treatment of newborn babies with sepsis

A global observational study, which involved more than 3,200 newborn babies suffering from sepsis in 19 hospitals in 11 countries, has shown that many newborns are dying because the antibiotics used to treat sepsis are losing their effectiveness.

8 Jun 2023

Debt deal leaves health programs (mostly) intact

A final deal cut between President Joe Biden and House Republicans extends the U.S. debt ceiling deadline to 2025 and reins in some spending.

8 Jun 2023

Experimental drug may slow the progression of atherosclerosis

An experimental drug already tested as a potential treatment for cancer, lung disease, and Alzheimer's disease may slow the progression of atherosclerosis that leads to heart disease, a new study shows.

8 Jun 2023

Study finds a dramatic increase in the use of non-LSD hallucinogens among young adults

Young adults ages 19 to 30 nearly doubled their past 12-month use of non-LSD hallucinogens in the United States from 2018 to 2021, according to a study by the University of Michigan and Columbia University.

8 Jun 2023

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Researchers evaluated the presence of coronavirus disease 2019 (COVID-19) drugs in river water.

8 Jun 2023

Teaming up with the patient’s immune system to combat cancer

The fact that our immune systems capture and destroy nanoparticles and the drugs they carry has been a problem in the field of nanomedicine for some time. But, in the fight against cancer, researchers are now attempting to exploit this problem to their advantage.

8 Jun 2023

Single virus binds to a single receptor, study reveals

In Europe, the pandemic triggered in 2020 by the SARS-CoV-2 coronavirus is now largely under control. But why this virus is able to spread so efficiently remains unclear. A team of researchers led by Dr. Simone Backes, Dr. Gerti Beliu and Prof. Dr. Markus Sauer of the Julius Maximilians University of Würzburg (JMU) has now shown in a publication in "Angewandte Chemie" that some previous assumptions need to be reconsidered.

8 Jun 2023

Drugs News and Research

Researchers discover how a sugar molecule can affect cancer cell response to chemoradiotherapy

Study:Overactive inflammatory response could be at the root of many long COVID cases

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Using Src N-terminal regulatory element as potential oncotarget

PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia

New model can quickly screen large libraries of potential drug compounds

Innovative 'village in a dish' system can accelerate stem cell research

SARS-CoV-2 hijacks body's metabolism to amplify COVID-19 severity

Exploring the viability of a new treatment for vascular dementia

Gut health boost: Functional foods and herbs show promise in tackling SARS-CoV-2 variants

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Study shows how blood makes the brain’s immune cells toxic

First-in-class drug shows promise as a safe and effective treatment for cannabis use disorder

Global study provides high-quality data to improve treatment of newborn babies with sepsis

Debt deal leaves health programs (mostly) intact

Experimental drug may slow the progression of atherosclerosis

Study finds a dramatic increase in the use of non-LSD hallucinogens among young adults

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Teaming up with the patient’s immune system to combat cancer

Single virus binds to a single receptor, study reveals

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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