Immune System News and Research

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Targeted drug combined with immunotherapy prolongs survival in patients with advanced kidney cancer

Patients with advanced kidney cancer, who received a targeted drug combined with a checkpoint-blocker immunotherapy agent had longer survival than patients treated with the standard targeted drug, said an investigator from Dana-Farber Cancer Institute, reporting results from a phase 3 clinical trial.

13 Feb 2021

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Tumor cells are able to avoid the attack of the immune system through several mechanisms. For instance, these can secrete factors that turn macrophages -cells in the immune system- into dual action agents that contribute to the tumor progress and will protect it from immune body defenses: these become, thus, the tumor-associated macrophages (TAMs).

13 Feb 2021

Study sheds light on the recurrence of herpes simplex virus

Researchers at the University of Virginia School of Medicine have shed light on what causes herpes simplex virus to flare up, explaining how stress, illness and even sunburn can trigger unwanted outbreaks.

12 Feb 2021

New article reviews how the circadian clock controls various aspects of homeostasis

Subconsciously, our bodies keep time for us through an ancient means - the circadian clock. A new University of California, Irvine-led article reviews how the clock controls various aspects of homeostasis, and how organs coordinate their function over the course of a day.

12 Feb 2021

Study shows that SRC-3 also regulates human immune T regulatory cells

A study led by researchers at Baylor College of Medicine reveals a novel role of the steroid receptor coactivator 3 (SRC-3/NCOA3), a protein crucial for steroid hormone function and a prognostic marker for aggressive human breast and other cancers.

12 Feb 2021

Researchers identify a pathway used by filoviruses to enter cells

It was once thought that Ebola and related filoviruses were more or less contained to Central Africa.

11 Feb 2021

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

Scientists from Scientific and Educational Center & Smart Materials and Biomedical Applications under the leadership of Kateryna Levada together with colleagues from Center for Immunology and Cellular Biotechnology of the Immanuel Kant Baltic Federal University conducted a joint interdisciplinary study on the development of a new method for treating leukemia using nanomaterials.

11 Feb 2021

New genetic analysis reveals biological causes of muscle weakness in older people

A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility.

11 Feb 2021

STING activation may be a new approach to reduce graft-versus-host disease

MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

11 Feb 2021

Variants of nine genes induce a higher risk of developing Addison's disease

Variants of nine genes increase the risk of developing Addison's disease, a rare disease in which the immune system attacks the adrenal glands.

11 Feb 2021

New review summarises effect of aquatic pollution on cancer prevalence in wild animals

The recent review, published in Environment International and led by the University of Tartu, summarises the effect of aquatic pollution on cancer prevalence in wild animals with the help of more than 300 reviewed studies.

11 Feb 2021

Minimally-invasive deep aging clocks could improve response to COVID-19 vaccine

Deep Longevity, a fully-owned subsidiary of Regent Pacific (SEHK:0575.HK), specializing in the development and the application of next-generation artificial intelligence (AI) for aging and longevity research, today announced the publication of an article in Lancet Healthy Longevity titled "The potential of rapalogs to enhance resilience against SARS-CoV-2 infection and reduce the severity of COVID-19".

11 Feb 2021

Single strain of bacteria may reduce the severity of graft-versus-host disease

MUSC Hollings Cancer Center researchers found that a single strain of bacteria may be able to reduce the severity of graft-versus-host disease (GVHD), as reported online in February 2021 in JCI Insight.

11 Feb 2021

Study provides new insights into the mechanism of bone marrow tissue

Imagine a day when clinicians treating people with blood diseases such as leukemia or multiple myeloma can send in requests for laboratories to custom-produce specific types of blood cells to replace those affected by the disease.

10 Feb 2021

Study could help develop drugs for pregnancy maintenance, treat autoimmune diseases

A team of scientists from Immanuel Kant Baltic Federal University with their colleagues from the Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences (Perm) studied the effect of trophoblastic β1-glycoprotein in the blood of pregnant women on pro-inflammatory immune cells.

10 Feb 2021

Scientists make four major discoveries about SARS-CoV-2

University of Minnesota Medical School researchers studied SARS-CoV-2 infections at individual cellular levels and made four major discoveries about the virus, including one that validates the effectiveness of remdesivir - an FDA-approved antiviral drug - as a form of treatment for severe COVID-19 disease.

10 Feb 2021

Chocolate-flavored e-cigarettes are 'particularly harmful' to the lungs, study shows

New research shows chocolate-flavored e-cigarettes are "particularly harmful" to the lungs. In fact, scientists found all 10 flavors tested caused some level of toxicity in the cells lining the lungs, resulting in cell death in some instances.

10 Feb 2021

Exposure to seasonal coronaviruses does not produce antibodies that protect against SARS-CoV-2

Past exposure to seasonal coronaviruses (CoVs), which cause the common cold, does not result in the production of antibodies that protect against the novel coronavirus SARS-CoV-2, according to a study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2021

Freiburg immunologists decipher anti-cancer drug's mode of operation

Rituximab, an anti-cancer drug targeting the membrane protein CD20, was the first approved therapeutic antibody against B tumor cells. Immunologists at the University of Freiburg have now solved a mystery about how it works.

10 Feb 2021

Inherited genetic variation may affect the response to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer.

10 Feb 2021

Immune System News and Research

Targeted drug combined with immunotherapy prolongs survival in patients with advanced kidney cancer

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Study sheds light on the recurrence of herpes simplex virus

New article reviews how the circadian clock controls various aspects of homeostasis

Study shows that SRC-3 also regulates human immune T regulatory cells

Researchers identify a pathway used by filoviruses to enter cells

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

New genetic analysis reveals biological causes of muscle weakness in older people

STING activation may be a new approach to reduce graft-versus-host disease

Variants of nine genes induce a higher risk of developing Addison's disease

New review summarises effect of aquatic pollution on cancer prevalence in wild animals

Minimally-invasive deep aging clocks could improve response to COVID-19 vaccine

Single strain of bacteria may reduce the severity of graft-versus-host disease

Study provides new insights into the mechanism of bone marrow tissue

Study could help develop drugs for pregnancy maintenance, treat autoimmune diseases

Scientists make four major discoveries about SARS-CoV-2

Chocolate-flavored e-cigarettes are 'particularly harmful' to the lungs, study shows

Exposure to seasonal coronaviruses does not produce antibodies that protect against SARS-CoV-2

Freiburg immunologists decipher anti-cancer drug's mode of operation

Inherited genetic variation may affect the response to cancer immunotherapy

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