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Arcus Biosciences announces presentation of final results from Phase 1 study of AB928 at ESMO 2018

Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company focused on creating innovative cancer immunotherapies, today announced that it will present final results from the Phase 1 study of AB928, its dual adenosine receptor antagonist, in healthy volunteers during a poster display session at the European Society of Medical Oncology 2018 Congress, being held October 19-23, 2018, in Munich, Germany.

8 Oct 2018

Study suggests novel approach to treating adults with autism spectrum disorder

A team of scientists at Florida Atlantic University has uncovered a brain-signaling pathway that can be pharmacologically manipulated in genetically engineered mice to reverse an autism-related pathway.

8 Oct 2018

Scientists develop micron-sized spheres that catch and destroy contaminants in water

Rice University scientists have developed something akin to the Venus' flytrap of particles for water remediation.

6 Oct 2018

Research reveals new details of HIV life cycle

Research by a multi-institutional team, including two members from the University of Delaware, has revealed new details about the HIV virus capsid structure and how it develops.

5 Oct 2018

Scripps Research scientists discover role of immune system double agent

Scientists at Scripps Research have discovered the role of an immune system double agent. This molecule, called USP18, can help curtail immune responses, but it can also open the door to bacterial infections, such as harmful listeria and staph infections.

5 Oct 2018

Krembil scientists develop potential treatment to stop knee and spine osteoarthritis

Scientists at the Krembil Research Institute have developed a novel therapeutic treatment that has the potential to stop knee and spine osteoarthritis in its tracks.

5 Oct 2018

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden has decoded the regulatory impact on neuronal survival of a small non-coding RNA molecule, so-called miRNA, at the highest resolution to date.

4 Oct 2018

Scientists discover key insights into how sperm and egg cells are formed

Key insights into how sperm and egg cells are formed have been discovered by scientists, shedding light on the earliest stages of their development.

4 Oct 2018

Stevens researchers develop new class of molecules for breast cancer treatment

Researchers at Stevens Institute of Technology and colleagues have designed and developed a new class of molecules that use a never-before-known mechanism that may halt or destroy breast cancer tumors, particularly for patients with drug-resistant or dangerously metastatic stages of the disease.

4 Oct 2018

New ReFRAME drug repurposing collection offers hope for treating major diseases

Each year, millions of people worldwide suffer from potentially fatal infectious diseases that often leave survivors facing a lifetime of related health problems. But what if drugs against such diseases already existed but nobody knew it?

4 Oct 2018

Newly discovered compounds may explain whole grain health benefits

Scientists have discovered new compounds that may explain whole grain health benefits, reports a new study led by the University of Eastern Finland.

3 Oct 2018

Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesity

The Neurobiotechnology research team of the Universitat Jaume I in Castellón, Spain, headed by professor Ana María Sánchez, has proven the positive effects of a vegetable hormone, helping reverse brain alterations caused by high-fat diets, type-2 diabetes, obesity and physical inactivity.

3 Oct 2018

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that it has submitted a Clinical Trial Authorization application to the Medicines and Healthcare products Regulatory Agency to initiate a Phase 1/2 study of ALN-AAT02, an investigational RNAi therapeutic targeting alpha-1 antitrypsin for the treatment of AAT deficiency-associated liver disease.

3 Oct 2018

Natural compound found in grapes may protect against cancer

Lung cancer is the deadliest form of cancer in the world, and 80% of death are related to smoking. In addition to tobacco control, effective chemoprevention strategies are therefore needed.

3 Oct 2018

Molecule research reveals potential drug target for treating stroke patients

In an extension of research published a month ago in Nature Methods, a novel hybrid approach performed by researchers from Clemson University's department of physics and astronomy and Stony Brook University has revealed a 3-D structure of a protein fragment that could serve as a drug target in treating stroke patients.

3 Oct 2018

New way of using natural killer cells makes immunotherapy viable to more patients

Immunotherapy is making headlines for saving the lives of hundreds of cancer patients including former President Jimmy Carter. But many of these therapies, only work for a small portion of people who have a specific molecule called PDL1 in their cancer makeup.

3 Oct 2018

Study identifies camelid nanobodies capable of blocking EGF in cancer cells

The natural world often provides the answer to unsolved medical problems. On this occasion, the solution to a challenge posed by cancer has come about from the immune system of camelids.

3 Oct 2018

Understanding immune system's balancing act could help in prevention, treatment of IBD

Australian researchers have uncovered clues in the immune system that reveal how the balance of 'good' gut bacteria is maintained. This information could help in the prevention and treatment of inflammatory bowel disease.

3 Oct 2018

Researchers discover how nerve cells control movement

Researchers at Karolinska Institutet in Sweden have discovered a new way in which nerve cells can control movement. In a study on zebrafish published in the journal PNAS they show that the contact between neurons and muscles is more dynamic than previously thought.

3 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Molecule News and Research

Arcus Biosciences announces presentation of final results from Phase 1 study of AB928 at ESMO 2018

Study suggests novel approach to treating adults with autism spectrum disorder

Scientists develop micron-sized spheres that catch and destroy contaminants in water

Research reveals new details of HIV life cycle

Scripps Research scientists discover role of immune system double agent

Krembil scientists develop potential treatment to stop knee and spine osteoarthritis

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

Scientists discover key insights into how sperm and egg cells are formed

Stevens researchers develop new class of molecules for breast cancer treatment

New ReFRAME drug repurposing collection offers hope for treating major diseases

Newly discovered compounds may explain whole grain health benefits

Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesity

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Natural compound found in grapes may protect against cancer

Molecule research reveals potential drug target for treating stroke patients

New way of using natural killer cells makes immunotherapy viable to more patients

Study identifies camelid nanobodies capable of blocking EGF in cancer cells

Understanding immune system's balancing act could help in prevention, treatment of IBD

Researchers discover how nerve cells control movement

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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