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Small increases in physical exercise can lower chances for major mobility loss in older adults

Adding 48 minutes of moderate exercise per week is associated with improvements in overall physical functioning and decreases in risks of immobility in older adults who are sedentary, finds a new study led by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.

11 Sep 2017

Researchers create first realistic model of the heart to simulate arrhythmia

A group of researchers from MIPT and Ghent University(Belgium) has developed the first realistic model able to reproduce the complexity of the cardiac microstructure.

11 Sep 2017

Researchers identify factors that predict frailty transitions in older men

As we age, we may be less able to perform daily activities because we may feel frail, or weaker than we have in the past. Frailer older adults may walk more slowly and have less energy. Frailty also raises a person's risks for falling, breaking a bone, becoming hospitalized, developing delirium, and dying.

8 Sep 2017

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers from the Perelman School of Medicine at the University of Pennsylvania have made a discovery about muscular dystrophy disorders that suggest new possibilities for treatment.

7 Sep 2017

Scientists directly convert skin cells from healthy adults into motor neurons

Scientists working to develop new treatments for neurodegenerative diseases have been stymied by the inability to grow human motor neurons in the lab. Motor neurons drive muscle contractions, and their damage underlies devastating diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy, both of which ultimately lead to paralysis and early death.

7 Sep 2017

Researchers find correlation between shorter telomeres and presence of heart failure

Each cell in the average human body contains 23 pairs of chromosomes, with four telomeres on each pair. Telomeres cover the end of the chromosome, protecting it from deterioration or fusion with adjacent chromosomes, much like the plastic tip at the end of a shoelace protects it from unraveling.

7 Sep 2017

Fatty acid-derived bioactive molecule helps improve heart function after heart attack in mice

Heart attacks provoke an acute immune response. Leukocytes rush to the heart muscle to remove dead cells and begin building scar tissue. This is followed by a second immune response, the resolving phase that allows healing.

7 Sep 2017

Researchers study two new drugs to find alternative treatment for men with erectile dysfunction

Close to 70 percent of men with erectile dysfunction (ED) respond to the ED drug sildenafil. However, only about 50 percent of men with diabetes- a population commonly affected by ED- achieve positive results with sildenafil.

6 Sep 2017

Parkinson’s disease detection by simple smell or drawing tests find two parallel studies

According to a latest study from the Michigan State University, a simple “scratch and sniff” test could be enough to predict Parkinson’s disease before it starts is debilitating curse.

6 Sep 2017

Substances in coffee could help quash risk of developing diabetes

In recent years, researchers have identified substances in coffee that could help quash the risk of developing Type 2 diabetes. But few of these have been tested in animals. Now in study appearing in ACS' Journal of Natural Products, scientists report that one of these previously untested compounds appears to improve cell function and insulin sensitivity in laboratory mice.

6 Sep 2017

First realistic heart model may help better understand onset of cardiac arrhythmias

A group of researchers from MIPT and Ghent University (Belgium) has developed the first realistic model able to reproduce the complexity of the cardiac microstructure.

6 Sep 2017

Researcher develops bone marrow models to study hematological and musculoskeletal diseases

For her research on the development of hematological and musculoskeletal disorders, Dr. Cornelia Lee-Thedieck, scientist at Karlsruhe Institute of Technology, is awarded an ERC Starting Grant: The European Research Council decided to fund her project "bloodANDbone" with EUR 1.5 million for five years. At KIT's Institute of Functional Interfaces, Lee-Thedieck develops models of the human bone marrow to study the regeneration of blood and bone by stem cells and how this regeneration is disturbed in diseases like leukemia or bone metastases.

6 Sep 2017

Existing antidepressant drug could slow progression of Parkinson’s

Michigan State University scientists now have early proof that an antidepressant drug that's been around for more than 50 years could slow the progression of Parkinson's.

6 Sep 2017

Researchers discover anatomical variations in neck musculature linked to nTOS symptoms

Neurogenic thoracic outlet syndrome (nTOS) is a common neurologic syndrome resulting in pain, numbness, and/or weakness in the arm, forearm, and hand. This condition affects 0.3-8.0% of the U.S. population, and is generally caused by impingement of nerves traveling from the brachial plexus in the neck, through a region referred to as the thoracic outlet.

5 Sep 2017

Ketogenic diet prolongs life and improves memory and physical functions in aged mice find researchers

A pair of new studies find that diets termed ketogenic that are classically low in carbohydrates can prolong life in adult male laboratory mice. In addition this ketogenic diet also preserves the memory functions as well as muscle masses of the aged mice that were fed on it. The mechanism behind this could be the fact that ketogenic diet induces protein acetylation in the mice liver and muscles.

5 Sep 2017

Study reveals benefits of defibrillators in heart disease patients treated with CRT

Some heart disease patients who are treated with cardiac resynchronization therapy (CRT) would live longer and have fewer hospital admissions if they also received a defibrillator, concludes a team of researchers led by Aston Medical School at Aston University.

5 Sep 2017

Muscle News and Research

Small increases in physical exercise can lower chances for major mobility loss in older adults

Researchers create first realistic model of the heart to simulate arrhythmia

Researchers identify factors that predict frailty transitions in older men

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Scientists directly convert skin cells from healthy adults into motor neurons

Researchers find correlation between shorter telomeres and presence of heart failure

Fatty acid-derived bioactive molecule helps improve heart function after heart attack in mice

Researchers study two new drugs to find alternative treatment for men with erectile dysfunction

Parkinson’s disease detection by simple smell or drawing tests find two parallel studies

Substances in coffee could help quash risk of developing diabetes

First realistic heart model may help better understand onset of cardiac arrhythmias

Researcher develops bone marrow models to study hematological and musculoskeletal diseases

Existing antidepressant drug could slow progression of Parkinson’s

Researchers discover anatomical variations in neck musculature linked to nTOS symptoms

Ketogenic diet prolongs life and improves memory and physical functions in aged mice find researchers

Study reveals benefits of defibrillators in heart disease patients treated with CRT

Combined DNA and protein 'liquid biopsy' more accurate in identifying early-stage pancreatic cancer

CSHLP publishes new book on The Biology of Exercise

New study finds lack of adherence to lifesaving treatment among breast cancer patients on opioids

Fat may influence cancer development in diverse ways

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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