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UC San Diego Health treats first cancer patient with iPSC-derived cell therapy

After 10 years in remission, Derek Ruff's cancer returned, this time as stage IV colon cancer. Despite aggressive rounds of chemotherapy, palliative radiotherapy and immunotherapy, his disease progressed.

2 Apr 2019

Pitt study sheds light on how immune cells help tumors to escape body's defenses

New research from the University of Pittsburgh School of Medicine and the UPMC Hillman Cancer Center sheds light on how tumors use the body's regulators of immunity for their own benefit.

2 Apr 2019

Potential drug targets cause of adult-onset muscular dystrophy

People diagnosed with myotonic dystrophy type 1 have difficulty unclenching muscles due to a genetic defect that generates toxic material within their cells.

1 Apr 2019

Study reveals investigational drug as effective treatment for relapsed marginal zone lymphoma

A study at The University of Texas MD Anderson Cancer Center revealed the investigational drug umbralisib as an effective treatment for patients with relapsed marginal zone lymphoma.

1 Apr 2019

EU-funded researchers develop 'nano-vehicle' to deliver life-saving drugs

Despite many successes, modern medicine is still struggling to find effective treatments for serious pathologies such as cancer and neurodegenerative and inflammatory diseases. For Alzheimer’s disease, for example, only 30% of patients respond to therapy whereas for cancers the figure is only 25%.

1 Apr 2019

Neuroscientists develop new model to trial preventative treatments for schizophrenia

Neuroscientists at The University of Queensland have developed a new animal model of schizophrenia that will enable researchers around the world to better understand the disease and develop new treatments.

30 Mar 2019

UA immunobiology professor will use $1.9 million grant to study copper's therapeutic potential

Pneumonia starts like this: A bacterial cell called Streptococcus pneumoniae enters the nostril. It travels down the nasal passage and into the lungs, where a war begins. In the lungs, S. pneumoniae encounters immune cells called macrophages, which will do whatever they can to fight it off.

29 Mar 2019

APS-ASPET Presidential Symposium Series spotlights advances in gut microbiome research

Leading physiology and pharmacology researchers will speak in a four-part series centered on the gut microbiome--the microbe population living in the digestive tract--and its role in wound recovery, hypertension and nervous system function.

29 Mar 2019

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Queen’s University Belfast and Domainex are pleased to announce that their joint project team has successfully identified novel first-in-class small molecule inhibitors of the anti-apoptotic protein FLIP.

29 Mar 2019

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

The U.S. Army Medical Research Institute of Infectious Diseases today announced that, for the first time, the U.S. Food and Drug Administration has provided formal regulatory agreement for use of an animal model to support development of a drug candidate, remdesivir, for treating deadly Ebola virus infections.

29 Mar 2019

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

A pioneering clinical trial investigating medicinal cannabis as a potential treatment for people living with severe Tourette syndrome will be conducted by Wesley Medical Research, in Brisbane in Australia, with cannabis supply facilitated by Lambert Initiative for Cannabinoid Therapeutics at University of Sydney.

28 Mar 2019

Garvan researchers develop more accurate method to diagnose cancer subtypes

Developed by researchers at the Garvan Institute of Medical Research, this potential diagnostic method screens a cancer sample for 'fusion genes', estimated to be linked to one in five cancers, and may provide a more accurate snapshot of rearranged DNA found in cancer.

28 Mar 2019

FDA approves new oral treatment for men with certain forms of hypogonadism

The U.S. Food and Drug Administration today approved Jatenzo (testosterone undecanoate), an oral testosterone capsule to treat men with certain forms of hypogonadism.

27 Mar 2019

Researchers unravel biomechanics of Ebola virus-host cell adhesion

It was recently reported that the number of Ebola cases in the Democratic Republic of Congo has surpassed 1,000, making it the second-worst outbreak in history after the 2014 outbreak in West Africa in which 29,000 people were infected and more than 11,000 died.

27 Mar 2019

Prostate cancer cells 'spit out' a protein that promotes tumor growth

Prostate cancer cells change the behavior of other cells around them, including normal cells, by 'spitting out' a protein from their nucleus, new research has found.

26 Mar 2019

LNC Therapeutics announces grant of Cornell University patent relating to christensenella bacteria

LNC Therapeutics, a French biotech company specializing in gut microbiome-based drug discovery, announced today the grant of the Cornell University (Ithaca, New-York, USA) patent relating to christensenella bacteria.

26 Mar 2019

VCU researchers home in on microRNA processing for new cancer therapies

More than a decade of research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs.

26 Mar 2019

BU researchers identify biomarker and possible new therapy for melanoma

Researchers have identified a biomarker and a possible new therapy for melanoma.

26 Mar 2019

Shaping new treatments for tuberculosis

To commemorate World TB Day, a Special Collection has been released by PLOS Medicine containing a series of articles that articulate the essential new steps in clinical research that will pave the way for the development of tomorrow's optimal treatment for all forms of tuberculosis.

25 Mar 2019

Cerveau announces research collaboration agreement with Eisai for novel tau imaging agent

Cerveau Technologies, Inc. today announced a research collaboration agreement with Eisai Inc., which will enable Eisai to use Cerveau's [F-18]MK-6240, an investigational imaging agent, in Positron Emission Tomography scans to assess the status and progression of neurofibrillary tangles in the brain.

25 Mar 2019

Therapeutics News and Research

UC San Diego Health treats first cancer patient with iPSC-derived cell therapy

Pitt study sheds light on how immune cells help tumors to escape body's defenses

Potential drug targets cause of adult-onset muscular dystrophy

Study reveals investigational drug as effective treatment for relapsed marginal zone lymphoma

EU-funded researchers develop 'nano-vehicle' to deliver life-saving drugs

Neuroscientists develop new model to trial preventative treatments for schizophrenia

UA immunobiology professor will use $1.9 million grant to study copper's therapeutic potential

APS-ASPET Presidential Symposium Series spotlights advances in gut microbiome research

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Study provides framework for developing Ebola virus therapeutic under FDA Animal Rule

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

Garvan researchers develop more accurate method to diagnose cancer subtypes

FDA approves new oral treatment for men with certain forms of hypogonadism

Researchers unravel biomechanics of Ebola virus-host cell adhesion

Prostate cancer cells 'spit out' a protein that promotes tumor growth

LNC Therapeutics announces grant of Cornell University patent relating to christensenella bacteria

VCU researchers home in on microRNA processing for new cancer therapies

BU researchers identify biomarker and possible new therapy for melanoma

Shaping new treatments for tuberculosis

Cerveau announces research collaboration agreement with Eisai for novel tau imaging agent

Industry Focus eBook - Biotechnology (4th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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