Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Early onset of dietary treatment may slow down progression of Alzheimer's disease

New research findings indicate that an early onset of dietary treatment may slow down the progression of Alzheimer's disease. The study was conducted on mice, and the results will be published in the February issue of Journal of Nutritional Biochemistry. Researchers from the University of Eastern Finland played a key role in the study, which was carried out as part of the LiPiDiDiet project funded by the European Union.

24 Jan 2014

Early onset of dietary treatment may slow down progression of Alzheimer's, says research

24 Jan 2014

Scientists identify critical regulator of molecule deeply involved in progression of Alzheimer's

Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer's disease.

24 Jan 2014

Scientists identify molecules that block accumulation of toxic eye protein responsible for early onset of glaucoma

Using a novel high-throughput screening process, scientists have for the first time identified molecules with the potential to block the accumulation of a toxic eye protein that can lead to early onset of glaucoma.

24 Jan 2014

Scientists identify critical regulator of molecule involved in progression of Alzheimer’s disease

Scientists from the Florida campus of The Scripps Research Institute have identified a critical regulator of a molecule deeply involved in the progression of Alzheimer’s disease.

23 Jan 2014

People with higher levels of omega-3 fatty acids may have larger brain volumes in old age

People with higher levels of the omega-3 fatty acids found in fish oil may also have larger brain volumes in old age equivalent to preserving one to two years of brain health, according to a study published in the January 22, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. Shrinking brain volume is a sign of Alzheimer's disease as well as normal aging.

23 Jan 2014

Research reveals why people lose hearing as they become old

Although the brain becomes smaller with age, the shrinkage seems to be fast-tracked in older adults with hearing loss, according to the results of a study by researchers from Johns Hopkins and the National Institute on Aging. The findings add to a growing list of health consequences associated with hearing loss, including increased risk of dementia, falls, hospitalizations, and diminished physical and mental health overall.

23 Jan 2014

EnVivo Pharmaceuticals starts encenicline Phase 3 study in patients with Alzheimer's disease

EnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel therapies for central nervous system diseases, today announced it has initiated COGNITIV AD, a Phase 3 clinical program evaluating its novel alpha-7 (α7) potentiator, encenicline-hydrochloride (EVP-6124), in patients with Alzheimer's disease. The program is being conducted under a Special Protocol Assessment agreement with the FDA.

22 Jan 2014

Scientists identify specific enzyme essential for brain development

Scientists from the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna have identified a specific enzyme, histone deacetylase 2 (HDAC2), as essential for brain development. The findings published in Development are important to advance the development of new drugs to treat neurological diseases.

22 Jan 2014

Italian biochemist receives Louis-Jeantet Prize for Medicine for the year 2014

The 2014 LOUIS-JEANTET PRIZE FOR MEDICINE is awarded to the Italian biochemist Elena Conti, Director of the Department of Structural Cell Biology at the Max-Planck Institute of Biochemistry in Munich (Germany) and to Denis Le Bihan, the French medical doctor, physicist and Director of NeuroSpin, an institute at the French Nuclear and Renewable Energy Commission (CEA) at Saclay near Paris.

22 Jan 2014

Researchers demonstrate existence of an epigenetic lesion in hippocampus of Alzheimer patients

Alzheimer's disease can reach epidemic range in the coming decades, by the increasing average age of society. There are two key issues for Alzheimer's disease: there is currently no effective treatment and it has been described very few associated genetic changes (mutations) which reduces the number of targets for future therapies.

22 Jan 2014

Forest Laboratories third quarter net sales increase 24.9% to $846.8 million

Forest Laboratories, Inc., a leading, fully integrated, specialty pharmaceutical company largely focused on the United States market, announced that reported diluted earnings per share equaled $0.07 in the third quarter of fiscal 2014, compared to a reported loss per share of ($0.58) in the third quarter of fiscal 2013. The third quarter of fiscal 2014 included a $45 million charge ($28.2 million net of tax) related to Project Rejuvenate.

21 Jan 2014

Research shows how architecture of brain shapes its functioning

The structure of the human brain is complex, reminiscent of a circuit diagram with countless connections. But what role does this architecture play in the functioning of the brain?

20 Jan 2014

Researchers identify protein in brain that plays critical role in memory loss seen in Alzheimer's patients

Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted online today.

20 Jan 2014

President Obama signs law to increase funding for Alzheimer's research, education

At the urging of the Alzheimer's Association and its more than 600,000 advocates, the funding bill signed into law today by President Obama contained an unprecedented $122 million increase for Alzheimer's research, education, outreach and caregiver support. The Alzheimer's Association applauds the Obama administration for calling for increased Alzheimer's funding in the President's Fiscal Year 2014 budget and Congress for providing funding to enable the continued, effective implementation of the National Plan to Address Alzheimer's Disease.

18 Jan 2014

Researcher finds possible way to unravel misfolded proteins by reprogramming yeast protein

At the heart of brain diseases such as amyotrophic lateral sclerosis, Alzheimer's disease, and Parkinson's disease is protein misfolding, in which distorted proteins are unable to perform their normal functions. At present, there is no known way to reverse protein misfolding.

17 Jan 2014

Research uncovers new mechanism in brain cells that may help keep deadly neurological diseases in check

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, MD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years.

17 Jan 2014

Study explores the role of DNA in predisposing individuals to diseases

A group of international researchers, led by a research fellow in the Harvard Medical School-affiliated Institute for Aging Research at Hebrew SeniorLife, published a paper today in Cell describing a study aimed at better understanding how inherited genetic differences, or variants, predispose certain individuals to develop diseases such as type 2 diabetes.

16 Jan 2014

Research findings may offer new way to treat prion diseases

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, PhD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years.

16 Jan 2014

Heavy drinking associated with faster decline in cognitive function in middle-aged men

Middle-aged men who drink more than 36 grams of alcohol, or two and a half US drinks per day, may speed their memory loss by up to six years later on, according to a study published in the January 15, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

16 Jan 2014

Alzheimer's Disease News and Research

Further Reading

Early onset of dietary treatment may slow down progression of Alzheimer's disease

Early onset of dietary treatment may slow down progression of Alzheimer's, says research

Scientists identify critical regulator of molecule deeply involved in progression of Alzheimer's

Scientists identify molecules that block accumulation of toxic eye protein responsible for early onset of glaucoma

Scientists identify critical regulator of molecule involved in progression of Alzheimer’s disease

People with higher levels of omega-3 fatty acids may have larger brain volumes in old age

Research reveals why people lose hearing as they become old

EnVivo Pharmaceuticals starts encenicline Phase 3 study in patients with Alzheimer's disease

Scientists identify specific enzyme essential for brain development

Italian biochemist receives Louis-Jeantet Prize for Medicine for the year 2014

Researchers demonstrate existence of an epigenetic lesion in hippocampus of Alzheimer patients

Forest Laboratories third quarter net sales increase 24.9% to $846.8 million

Research shows how architecture of brain shapes its functioning

Researchers identify protein in brain that plays critical role in memory loss seen in Alzheimer's patients

President Obama signs law to increase funding for Alzheimer's research, education

Researcher finds possible way to unravel misfolded proteins by reprogramming yeast protein

Research uncovers new mechanism in brain cells that may help keep deadly neurological diseases in check

Study explores the role of DNA in predisposing individuals to diseases

Research findings may offer new way to treat prion diseases

Heavy drinking associated with faster decline in cognitive function in middle-aged men

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