Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Metformin can reduce risk of open-angle glaucoma in people with diabetes

Taking the medication metformin hydrochloride was associated with reduced risk of developing the sight-threatening disease open-angle glaucoma in people with diabetes, according to a study published online by JAMA Ophthalmology.

29 May 2015

Panorama SNP-based non-invasive prenatal test can detect complete molar pregnancy

Natera, Inc., a leader in non-invasive genetic testing, today announced a study published in Ultrasound in Obstetrics & Gynecology demonstrating that the Panorama single-nucleotide polymorphism (SNP)-based non-invasive prenatal test (NIPT) can identify a complete molar pregnancy in the first trimester.

From Natera 28 May 2015

College of American Pathologists recognized with ATD's Excellence in Practice Award

The College of American Pathologists was recognized by the Association for Talent Development, formerly ASTD, with an Excellence in Practice Award for its Laboratory Medical Director (LMD) Advanced Practical Pathology Program (AP3) in the Organizational Learning and Development category.

28 May 2015

Researchers present new program to evaluate clinical relevance of genetic variants

Millions of genetic variants have been discovered over the last 25 years, but interpreting the clinical impact of the differences in a person's genome remains a major bottleneck in genomic medicine. In a paper published in The New England Journal of Medicine on May 27, a consortium including investigators from Brigham and Women's Hospital and Partners HealthCare present ClinGen, a program to evaluate the clinical relevance of genetic variants for use in precision medicine and research.

27 May 2015

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular "lock" that the deadly Ebola virus must pick to gain entry to cells.

27 May 2015

Neuroscientists reveal inner workings of the brain in people with autism

Strapped into a motion-enabled simulator and wearing 3D glasses, 36 adolescent volunteers recently experienced what it was like to "travel" through a field of virtual stars. The experiments provided new and convention-busting data about how sensory stimuli are processed by the brains of individuals with Autism Spectrum Disorder.

27 May 2015

New adjustable female shoe based on smart materials may prevent common foot problems

A new adjustable female shoe based on a new memory shape composite of leather and Nitinol material, is now available. The new material allows fitting the shoe to the foot shape, after obtaining anthropometric measurements through the Shopintantshoe portable scanner and modifying it with the "Shoptool", a machine that completes the process directly in the shop.

26 May 2015

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Roche announced today that the US Food and Drug Administration has provided 510(k) clearance for the cobas Cdiff Test to detect Clostridium difficile (C. difficile) in stool specimens.

26 May 2015

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Removing accumulated mutant p53 protein from a cancer model showed that tumors regress significantly and survival increases. This finding, by an international team of cancer researchers led by Ute Moll, MD, Professor of Pathology at Stony Brook University School of Medicine, is reported in a paper published advanced online May 25 in Nature.

26 May 2015

Researchers discover new gene subgroup that drives prostate cancer

Prostate cancer researchers have drawn a molecular portrait that provides the first complete picture of localized, multi-focal disease within the prostate and also unveils a new gene subgroup driving it.

26 May 2015

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both of which are caused by a mutation in the a gene called C9ORF72.

24 May 2015

Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

An international collaboration of researchers are advancing precision medicine to men with advanced prostate cancer.

22 May 2015

Studies refine amyloid imaging role in dementia

Two meta-analyses published in JAMA help to define the role of amyloid imaging in dementia.

21 May 2015

Enterprise Therapeutics secures additional funding to accelerate drug discovery for treatment of respiratory diseases

ENTERPRISE THERAPEUTICS Ltd, a drug discovery company focused on new therapeutics for respiratory diseases, today announced that it has secured an additional £2.4m ($3.6m) in Series-A financing.

21 May 2015

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

A molecule that helps control gene expression may play a role in controlling chemotherapy resistance among patients with the most common form of ovarian cancer.

21 May 2015

UK Medical Device Companies in the Spotlight at the Medilink UK Awards 2015

News-Medical.net was proud to sponsor this year’s Medilink UK Innovation Award. The Innovation Award was presented to The Learning Clinic for their VitalPAC Nurse software platform which is used to capture patient observations in real time...

20 May 2015

Mi-Prostate Score improves prostate cancer detection

A new urine-based test improved prostate cancer detection - including detecting more aggressive forms of prostate cancer - compared to traditional models based on prostate serum antigen, or PSA, levels, a new study finds.

19 May 2015

Men with a history of asthma less likely to have aggressive prostate cancer

In what they are calling a surprising finding in a large study of men who completed questionnaires and allowed scientists to review their medical records, Johns Hopkins researchers report that men with a history of asthma were less likely than those without it to develop lethal prostate cancer.

19 May 2015

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Alnylam Pharmaceuticals, Inc. has announced that it has filed a Clinical Trial Application (CTA) with the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase 1/2 clinical trial with ALN-AAT, a subcutaneously administered investigational RNAi therapeutic targeting alpha-1 antitrypsin (AAT) for the treatment of AAT deficiency-associated liver disease (alpha-1 liver disease).

19 May 2015

Studies support use of ThyraMIR and ThyGenX to improve detection of benign/malignant thyroid nodules

Data will be presented at both Digestive Disease Week (DDW) and the American Association of Clinical Endocrinologists (AACE) annual medical meetings.

18 May 2015

Pathology News and Research

Further Reading

Metformin can reduce risk of open-angle glaucoma in people with diabetes

Panorama SNP-based non-invasive prenatal test can detect complete molar pregnancy

College of American Pathologists recognized with ATD's Excellence in Practice Award

Researchers present new program to evaluate clinical relevance of genetic variants

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

Neuroscientists reveal inner workings of the brain in people with autism

New adjustable female shoe based on smart materials may prevent common foot problems

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Researchers discover new gene subgroup that drives prostate cancer

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

Studies refine amyloid imaging role in dementia

Enterprise Therapeutics secures additional funding to accelerate drug discovery for treatment of respiratory diseases

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

UK Medical Device Companies in the Spotlight at the Medilink UK Awards 2015

Mi-Prostate Score improves prostate cancer detection

Men with a history of asthma less likely to have aggressive prostate cancer

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Studies support use of ThyraMIR and ThyGenX to improve detection of benign/malignant thyroid nodules

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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