Therapeutics News and Research

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New analysis highlights increasing focus of early-stage clinical trials on rare cancers

The proportion of early-stage drug trials tackling the biggest cancer killers has declined sharply since the early 1990s as less common tumor types receive increasing attention, according to new research to be presented during the International Congress on Targeted Anticancer Therapies 2019, taking place from today to 27 February in Paris, France.

25 Feb 2019

Cancer patients' HIV status should not affect their treatment

New articles published in CANCER, a peer-reviewed journal of the American Cancer Society, note that there is no medical justification to deny optimal cancer therapy to individuals with HIV.

25 Feb 2019

New identified biomarker predicts patients who might benefit from HER2-targeted agents

In an effort to further individualize therapy and avoid over-treating patients, researchers at the Johns Hopkins Kimmel Cancer Center report a new study using PET scans has identified a biomarker that may accurately predict which patients with one type of HER2-positive breast cancer might best benefit from standalone HER2-targeted agents, without the need for standard chemotherapy.

22 Feb 2019

PENTAX Medical introduces new electrosurgical and argon plasma coagulation platforms

PENTAX Medical announces the addition of new dedicated electrosurgical and argon plasma coagulation platforms – the ENDO ARC and ENDO PLUS – to its therapeutic accessories range.

From PENTAX Medical Company 21 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

Study shows therapeutic potential of VEGF-A mRNA for regenerative angiogenesis in humans

An international team of researchers from academia and the biopharma industry has published a Phase 1a/b study, showing the therapeutic potential of mRNA encoding for vascular endothelial growth factor A (VEGF-A) for regenerative angiogenesis in humans.

20 Feb 2019

Researchers develop new way to deliver treatment for cartilage regeneration

Researchers from Texas A&M University, led by Dr. Akhilesh K. Gaharwar, have developed a new way to deliver treatment for cartilage regeneration.

19 Feb 2019

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent of all inherited genetic diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, cystic fibrosis and polycystic kidney disease.

19 Feb 2019

Specialized lung cells appear in the developing fetus much earlier than previously thought

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.

19 Feb 2019

Fetal signaling pathways may offer future opportunities to treat lung damage

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study published this week in the Proceedings of the National Academy of Sciences reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.

18 Feb 2019

Single CRISPR treatment can safely and stably correct genetic disease

Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD) -- for more than a year in mice, despite observed immune responses and alternative gene editing outcomes.

18 Feb 2019

Scientists discover trigger that turns strep infections into devastating disease

Houston Methodist infectious disease scientists have discovered a previously unknown trigger that turns a relatively run-of-the-mill infection into a devastatingly ravenous, flesh-eating disease.

18 Feb 2019

Patented IU discovery to treat ARDS has been optioned to Theratome Bio

A patented Indiana University School of Medicine discovery that uses proteins, lipids and nucleic acids secreted by adult stem cells to treat Acute Respiratory Distress Syndrome, or ARDS, has been optioned to Theratome Bio, an Indianapolis-based life sciences company.

17 Feb 2019

MUSC researchers discover new mechanism for a class of anti-cancer drugs

Researchers at the Medical University of South Carolina reveal a novel binding site for a class of anti-cancer drugs known as E1 inhibitors. This finding could lead to the design of more efficient E1 inhibitors.

15 Feb 2019

Immune checkpoint molecule protects against future development of cancer

A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself.

15 Feb 2019

Researchers conduct extensive comparison of drugs used in treating neuroendocrine tumors

An increasing number of new anti-cancer drugs are made available each year. During the authorization process, such new drugs usually undergo comparisons to one, but only rarely to multiple established drugs.

14 Feb 2019

Researchers comprehensively sequence the human immune system

For the first time ever, researchers are comprehensively sequencing the human immune system, which is billions of times larger than the human genome. In a new study published in Nature from the Human Vaccines Project, scientists have sequenced a key part of this vast and mysterious system -- the genes encoding the circulating B cell receptor repertoire.

14 Feb 2019

Robots, AI to diagnose and treat patients soon

Soon the complaints about the short time doctors spend with their patients may be a thing of the past. Robots, artificial speakers (smart speakers like Siri or Alexa) and Artificial Intelligence (AI) could help lend an ear to patient complaints says a report from the NHS.

12 Feb 2019

Antibody-based treatment could improve cure rate for blood and immune disorders

An antibody-based treatment can gently and effectively eliminate diseased blood-forming stem cells in the bone marrow to prepare for the transplantation of healthy stem cells, according to a study in mice by researchers at the Stanford University School of Medicine.

12 Feb 2019

AbbVie, Teneobio enter into strategic transaction to develop potential treatment for multiple myeloma

AbbVie, Teneobio, Inc. and its affiliate TeneoOne, Inc. announced today that they have entered a global strategic transaction to develop and commercialize TNB-383B, a BCMA-targeting immunotherapeutic for the potential treatment of multiple myeloma.

12 Feb 2019

Therapeutics News and Research

New analysis highlights increasing focus of early-stage clinical trials on rare cancers

Cancer patients' HIV status should not affect their treatment

New identified biomarker predicts patients who might benefit from HER2-targeted agents

PENTAX Medical introduces new electrosurgical and argon plasma coagulation platforms

Why melanoma tumors in the brain may be worse?

Study shows therapeutic potential of VEGF-A mRNA for regenerative angiogenesis in humans

Researchers develop new way to deliver treatment for cartilage regeneration

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Specialized lung cells appear in the developing fetus much earlier than previously thought

Fetal signaling pathways may offer future opportunities to treat lung damage

Single CRISPR treatment can safely and stably correct genetic disease

Scientists discover trigger that turns strep infections into devastating disease

Patented IU discovery to treat ARDS has been optioned to Theratome Bio

MUSC researchers discover new mechanism for a class of anti-cancer drugs

Immune checkpoint molecule protects against future development of cancer

Researchers conduct extensive comparison of drugs used in treating neuroendocrine tumors

Researchers comprehensively sequence the human immune system

Robots, AI to diagnose and treat patients soon

Antibody-based treatment could improve cure rate for blood and immune disorders

AbbVie, Teneobio enter into strategic transaction to develop potential treatment for multiple myeloma

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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