Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New protein discovery may contribute to improving the diagnosis of Dementia with Lewy Bodies

A research team led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University has made a significant finding that sheds new light on Dementia with Lewy Bodies (DLB).

27 Jun 2025

New brain imaging benchmark may improve Alzheimer's detection in diverse populations

A team of researchers from the Keck School of Medicine of USC's Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) has identified a new brain imaging benchmark that may improve how researchers classify biologically meaningful changes associated with Alzheimer's disease, especially in Hispanic and non-Hispanic white populations.

26 Jun 2025

Sleep does not block brain response to screams and alarms

During sleep, the brain must achieve a delicate balance: disconnecting from sensory input to allow restorative functions, while remaining alert enough to wake if danger arises.

26 Jun 2025

Living in disadvantaged neighborhoods linked to Alzheimer’s biomarkers

People living in more disadvantaged neighborhoods may be more likely to have biomarkers for inflammation and Alzheimer's disease, according to a study published June 25, 2025, in Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2025

Parse Biosciences GigaLab to support Mount Sinai researchers in generating one of the largest Alzheimer's and Parkinson's single cell datasets

Parse Biosciences today announced their commitment to support researchers from the Icahn School of Medicine at Mount Sinai in generating one of the largest single cell datasets focused on understanding alternative splicing events in the cells of Alzheimer's and Parkinson's patients.

From Parse Biosciences 26 Jun 2025

TET1 identified as key regulator in cancer and chronic disease

Recent findings shed new light on the critical role of TET1, a pivotal player in epigenetic regulation, in the development and progression of various clinical diseases.

25 Jun 2025

Researchers link brain waste clearance to early Alzheimer’s damage

A crucial link between the brain's cleaning system and deterioration of neurons associated with Alzheimer's disease has been discovered by University of Queensland researchers.

25 Jun 2025

Enhanced Genomics and The ALBORADA Drug Discovery Institute partner to accelerate Alzheimer's drug discovery

Enhanced Genomics ('Enhanced'), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced a strategic partnership with The ALBORADA Drug Discovery Institute at the University of Cambridge.

25 Jun 2025

Newborns and Alzheimer's patients have elevated blood levels of phosphorylated tau

Newborn babies and patients with Alzheimer's disease share an unexpected biological trait: elevated levels of a well-known biomarker for Alzheimer's.

24 Jun 2025

Study identifies potential way to slow or block progression of age-related macular degeneration

A new study from Washington University School of Medicine in St. Louis identifies a possible way to slow or block progression of age-related macular degeneration, a leading cause of blindness in people over age 50.

24 Jun 2025

Diabetes drug semaglutide shows promise in reducing dementia risk

Researchers at the Case Western Reserve School of Medicine have found that semaglutide, a popular diabetes and weight-loss drug, may lower the risk of dementia in people with type 2 diabetes (T2D).

24 Jun 2025

Protective gene variant slows Alzheimer’s by taming brain inflammation

A rare gene mutation that delays Alzheimer's disease does so by damping inflammatory signaling in brain-resident immune cells, according to a preclinical study led by investigators at Weill Cornell Medicine.

23 Jun 2025

Assessment of insulin resistance using TyG index flags rapid cognitive decline in Alzheimer's patients

Insulin resistance detected by routine triglyceride-glucose (TyG) index can flag people with early Alzheimer's who are four times more likely to present rapid cognitive decline, according to new research presented at the European Academy of Neurology (EAN) Congress 2025.

22 Jun 2025

Researchers use electric fields to identify aged cells

Researchers from Tokyo Metropolitan University have created a new way of telling "aged" human cells apart from younger ones using electric fields.

21 Jun 2025

Study reveals intercellular flow as crucial factor in tissue mechanics

Water makes up around 60 percent of the human body. More than half of this water sloshes around inside the cells that make up organs and tissues. Much of the remaining water flows in the nooks and crannies between cells, much like seawater between grains of sand.

21 Jun 2025

Targeting ST6Gal-I shows promise in reducing Alzheimer’s disease pathology

A recent study published in Engineering has provided novel insights into the involvement of α2,6-sialylation in Alzheimer's disease (AD), revealing that the ablation of α2,6-sialyltransferase-I (ST6Gal-I), an enzyme responsible for α2,6-sialylation, can downregulate BACE1 expression and suppress the production of amyloid-β42 (Aβ42) plaques, which are hallmarks of AD.

20 Jun 2025

New 3D immunohistochemistry method enhances deep tissue imaging

Three dimensional immunohistochemistry (3D-IHC) has transformed our ability to visualize the spatial arrangement of cells and molecules in intact tissues.

19 Jun 2025

Why Alzheimer’s DNA tests don’t treat all populations equally

A major global study tested whether European-derived polygenic risk scores (PGS) for Alzheimer’s disease can predict risk across diverse populations. While PGS performed well in many groups, it was less accurate in individuals of sub-Saharan African and Indian ancestry, highlighting the urgent need for more inclusive genetic data.

19 Jun 2025

Study finds high levels of iron in the brains of people diagnosed with Down syndrome and Alzheimer's

Scientists at the USC Leonard Davis School of Gerontology have discovered a key connection between high levels of iron in the brain and increased cell damage in people who have both Down syndrome and Alzheimer's disease.

19 Jun 2025

Researchers identify key differences in Alzheimer's progression in humans and animal models

Although it is known that Alzheimer's disease can start up to 20 years before the first symptoms appear, the lack of knowledge about how it progresses prevents the development of effective treatments, as well as a clear diagnosis to confront this neurodegenerative disease, which origin is also unknown.

19 Jun 2025

Alzheimer's Disease News and Research

Further Reading

New protein discovery may contribute to improving the diagnosis of Dementia with Lewy Bodies

New brain imaging benchmark may improve Alzheimer's detection in diverse populations

Sleep does not block brain response to screams and alarms

Living in disadvantaged neighborhoods linked to Alzheimer’s biomarkers

Parse Biosciences GigaLab to support Mount Sinai researchers in generating one of the largest Alzheimer's and Parkinson's single cell datasets

TET1 identified as key regulator in cancer and chronic disease

Researchers link brain waste clearance to early Alzheimer’s damage

Enhanced Genomics and The ALBORADA Drug Discovery Institute partner to accelerate Alzheimer's drug discovery

Newborns and Alzheimer's patients have elevated blood levels of phosphorylated tau

Study identifies potential way to slow or block progression of age-related macular degeneration

Diabetes drug semaglutide shows promise in reducing dementia risk

Protective gene variant slows Alzheimer’s by taming brain inflammation

Assessment of insulin resistance using TyG index flags rapid cognitive decline in Alzheimer's patients

Researchers use electric fields to identify aged cells

Study reveals intercellular flow as crucial factor in tissue mechanics

Targeting ST6Gal-I shows promise in reducing Alzheimer’s disease pathology

New 3D immunohistochemistry method enhances deep tissue imaging

Why Alzheimer’s DNA tests don’t treat all populations equally

Study finds high levels of iron in the brains of people diagnosed with Down syndrome and Alzheimer's

Researchers identify key differences in Alzheimer's progression in humans and animal models

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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