Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study uncovers new molecular mechanisms linked to Alzheimer's cognitive decline

A research team at the University of Barcelona's Institute of Neurosciences (UBneuro) has discovered new molecular mechanisms related to the cognitive decline associated with Alzheimer's disease, the most common dementia.

26 May 2025

Insulin resistance in the brain may link Alzheimer’s and epilepsy

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer's disease and epilepsy and may be a linking factor between the two diseases.

22 May 2025

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy.

21 May 2025

Herpes virus infection linked to higher Alzheimer’s risk, study shows antiherpetic drugs may help

A large US case-control study found that people diagnosed with herpes simplex virus type 1 (HSV-1) had a higher risk of developing Alzheimer’s disease. Use of antiherpetic medications was associated with a reduced risk of Alzheimer’s in those with HSV-1.

21 May 2025

New Alzheimer's drug candidate reduces toxic protein and improves memory in mice models

As researchers work to improve treatment of Alzheimer's disease, new research by UCLA Health identified a candidate drug that reduces levels of a toxic form of a protein in the brain caused by the disease and improved memory in mice by boosting production of a protective protein.

20 May 2025

MIT researchers discover new potential drug targets for Alzheimer’s disease

By combining information from many large datasets, MIT researchers have identified several new potential targets for treating or preventing Alzheimer's disease.

20 May 2025

Headway in Alzheimer’s disease care: New guidance provides recommendations for use of anti-amyloid monoclonal antibodies

The new guidelines for the use of monoclonal antibodies (mAbs) published in Neurodegenerative Diseases, serve as exemplary clinical recommendations for clinicians and healthcare providers, supporting the advancement of Alzheimer's disease treatment in Switzerland.

From S. Karger AG 19 May 2025

Ground-breaking discovery reveals common master switch for brain-related diseases

The 21st edition of Sustainability Through Science and Technology Summit 2025 (SIPS 2025), dedicated to Prof. Aaron Ciechanover, Nobel Laureate in Chemistry, to be held in Cebu, Philippines, from 17-20 November 2025, has confirmed the participation of Davis Joseph as an invited summit plenary lecturer for his recent ground-breaking discovery of the common master switch for numerous brain-related diseases.

19 May 2025

New fruit fly study shows the whole-body impact of Alzheimer’s disease

While Alzheimer's disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body.

16 May 2025

Study offers new clues to early detection of frontotemporal dementia in middle age

Dementia usually affects older people, so when it occurs in middle age, it can be hard to recognize. The most common form is frontotemporal dementia (FTD), which is often mistaken for depression, schizophrenia, or Parkinson's disease before the correct diagnosis is reached.

16 May 2025

New drug candidate disrupts the link between herpes virus and Alzheimer’s disease

Studies suggesting that certain viral infections may influence the onset of Alzheimer's diseases are gaining attention. In this context, a domestic research team has succeeded in breaking the link between viral infection and Alzheimer's disease using a new treatment candidate.

16 May 2025

Targeting PME-1 may offer new strategies for treating neurological disorders and cancer

PME-1 is a protein that modifies other proteins by removing methyl groups, but high levels of PME-1 are observed in some diseases, including Alzheimer's disease (AD) and cancer.

16 May 2025

Disparities in access to novel infusion treatment for Alzheimer's disease revealed

Adoption of lecanemab, a novel infusion treatment for Alzheimer's disease (AD), has been disproportionately higher among patients who are male, white, from urban areas, and have higher socioeconomic status, new research suggests.

15 May 2025

New approach directly combats the progression of Alzheimer’s and ALS

Scientists at Northwestern University have developed a new approach that directly combats the progression of neurodegenerative diseases like Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

14 May 2025

New candidate compounds show promise for Alzheimer's and pain treatment

A study published in the Journal of Medicinal Chemistry presents a new family of candidate compounds for the treatment of Alzheimer's disease and pain, which have shown promising effects in animal models.

14 May 2025

BSO drug mimics anti-obesity effects of difficult sulfur amino acid restricted diet

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 7, 2025, titled "Pharmacological recapitulation of the lean phenotype induced by the lifespan-extending sulfur amino acid-restricted diet."

13 May 2025

Sedentary behavior linked to increased Alzheimer's risk in older adults

Over 6 million Americans are impacted by Alzheimer's disease, and researchers from Vanderbilt University Medical Center and the University of Pittsburgh are discovering how lifestyle habits can impact the likelihood of developing the disease.

13 May 2025

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

12 May 2025

Novel Alzheimer's therapy shows low risk of severe side effects

The Food and Drug Administration's approval in 2023 of lecanemab - a novel Alzheimer's therapy shown in clinical trials to modestly slow disease progression - was met with enthusiasm by many in the field as it represented the first medication of its kind able to influence the disease.

12 May 2025

Breakthrough discovery offers hope for treating neurodegenerative diseases

Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's.

12 May 2025

Alzheimer's Disease News and Research

Further Reading

Study uncovers new molecular mechanisms linked to Alzheimer's cognitive decline

Insulin resistance in the brain may link Alzheimer’s and epilepsy

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

Herpes virus infection linked to higher Alzheimer’s risk, study shows antiherpetic drugs may help

New Alzheimer's drug candidate reduces toxic protein and improves memory in mice models

MIT researchers discover new potential drug targets for Alzheimer’s disease

Headway in Alzheimer’s disease care: New guidance provides recommendations for use of anti-amyloid monoclonal antibodies

Ground-breaking discovery reveals common master switch for brain-related diseases

New fruit fly study shows the whole-body impact of Alzheimer’s disease

Study offers new clues to early detection of frontotemporal dementia in middle age

New drug candidate disrupts the link between herpes virus and Alzheimer’s disease

Targeting PME-1 may offer new strategies for treating neurological disorders and cancer

Disparities in access to novel infusion treatment for Alzheimer's disease revealed

New approach directly combats the progression of Alzheimer’s and ALS

New candidate compounds show promise for Alzheimer's and pain treatment

BSO drug mimics anti-obesity effects of difficult sulfur amino acid restricted diet

Sedentary behavior linked to increased Alzheimer's risk in older adults

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Novel Alzheimer's therapy shows low risk of severe side effects

Breakthrough discovery offers hope for treating neurodegenerative diseases

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