Genetic Information News and Research

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New tool enables big data analysis without specialized expertise in bioinformatics

A new data analysis tool developed by researchers at The University of Texas MD Anderson Cancer Center incorporates a user-friendly, natural-language interface to allow biomedical researchers without specialized expertise in bioinformatics or programming languages to conduct intuitive analysis of large datasets.

25 Sep 2020

DNA damage may occur far away from the point of incidence of radiation

Ultraviolet light endangers the integrity of human genetic information and may cause skin cancer. For the first time, researchers of Karlsruhe Institute of Technology have demonstrated that DNA damage may also occur far away from the point of incidence of the radiation.

14 Sep 2020

Exploring sex differences in gene expression

Males and females share the vast majority of their genomes. Only a sprinkling of genes, located on the so-called X and Y sex chromosomes, differ between the sexes. Nevertheless, the activities of our genes--their expression in cells and tissues--generate profound distinctions between males and females.

12 Sep 2020

Veterinary college scientists pinpoint genes that drive ovarian cancer

High-grade serious ovarian carcinoma (HGSOC) is the fifth-leading cause of cancer-related deaths in women in the United States, yet little is known about the origins of this disease.

12 Sep 2020

New project seeks to understand the origin and role of ecDNA in cancer development

A team of pediatric oncologists led by PD Dr. Anton G. Henssen has set out to further improve our understanding of the mechanisms involved in cancer development and disease progression.

8 Sep 2020

Prescribing treatments according to genetic differences could benefit children with asthma

Selecting treatments according to genetic differences could help children and teenagers with asthma, according to research presented at the European Respiratory Society International Congress.

7 Sep 2020

Two researchers from Bielefeld University receive ERC Starting Grants

The European Research Council has awarded ERC Starting Grants to two researchers from Bielefeld University.

5 Sep 2020

Bioengineering technique that boosts protein production could lead to effective COVID-19 vaccine

A bioengineering technique to boost production of specific proteins could be the basis of an effective vaccine against the novel coronavirus that causes COVID-19, new research suggests.

3 Sep 2020

Genomic analysis of specific E. coli strain can help develop potential vaccines

Foodborne pathogens are very common and usually benign, but certain virulent strains of pathogens can result in severe disease and even death.

3 Sep 2020

Study shows how genetics could improve safety and efficacy of drugs for COVID-19 treatment

Over the past few months, a number of drugs have been under investigation to treat COVID-19 without well-established safety or data to support these claims.

28 Aug 2020

New computational methods help find genetic causes of severe childhood brain disorders

A team of researchers at Children's Hospital of Philadelphia affiliated with the CHOP Epilepsy Neurogenetics Initiative have combined clinical information with large-scale genomic data to successfully link characteristic presentations of childhood epilepsies with specific genetic variants.

26 Aug 2020

Premenopausal women previously treated with radiation have worse breast cancer-specific survival

Among premenopausal women with breast cancer, those who were previously treated with radiation for a primary childhood, adolescent, or young adult cancer had worse breast cancer-specific survival.

26 Aug 2020

Study shows why certain genetically predisposed individuals do not develop heart disease

Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can lead to elevated cholesterol and increased risk for a premature heart attack.

20 Aug 2020

Regeneration of vascular cells is regulated by RNA-binding protein

Through their basic research, physicians at the Heart Center of the University Hospital Bonn have discovered how the communication between individual cells can be influenced with the help of a specific protein.

19 Aug 2020

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

ETH Zurich scientists have developed an RNA molecule that can be used in bone marrow cells to correct genetic errors that affect protein production.

18 Aug 2020

Study shows how bacteria become increasingly infectious under certain conditions

Bacteria that invade animal cells in order to multiply are widespread in nature. Some of these are pathogens of humans and animals. In the environment, they are often found inside unicellular organisms.

18 Aug 2020

Scientists hope to find clues about how life emerged by tinkering with its oldest components

"I'm fascinated with life, and that's why I want to break it."

15 Aug 2020

Study focuses on genetic neurological disorders that develop in children over time

A team of researchers at Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) further bridged the gap between genomic information and clinical outcome data by systematically linking genetic information with electronic medical records, focusing on how genetic neurological disorders in children develop over time.

12 Aug 2020

FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

Today, the U.S. Food and Drug Administration approved the first liquid biopsy companion diagnostic that also uses next-generation sequencing (NGS) technology to identify patients with specific types of mutations of the epidermal growth factor receptor (EGFR) gene in a deadly form of metastatic non-small cell lung cancer (NSCLC).

7 Aug 2020

Study reveals the genetic cause of congenital malformation

Study by the University of Bonn reveals that genetic information controls development of the urinary tract, rectum and genitals Spontaneous mutations of a single gene are likely to cause serious developmental disorders of the excretory organs and genitalia.