Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Scientists prove the “neuroprotective” function of p62 protein in a mouse model

Neurodegenerative diseases like Alzheimer’s and Parkinson’s are defined by pathogenic accumulation of toxic proteins in the brain.

1 Jul 2022

Neural effects of COVID-19 on depressive symptoms

A new study identifies brain abnormalities in patients who recovered from COVID-19.

28 Jun 2022

MRI-based machine learning approach can accurately predict Alzheimer’s disease

The research uses machine learning technology to look at structural features within the brain, including in regions not previously associated with Alzheimer's.

20 Jun 2022

Traumatic brain injury changes the connections between nerve cells across the entire brain

Scientists from the University of California, Irvine have discovered that an injury to one part of the brain changes the connections between nerve cells across the entire brain.

17 Jun 2022

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Researchers assessed the characteristics of the brain fog reported by some COVID-19 patients.

17 Jun 2022

Even mild respiratory COVID can affect the brain

In a recent study published in the journal Cell, researchers explored neurological symptoms and subsequent cognitive impairment experienced by survivors of mild respiratory coronavirus disease 2019 (COVID-19).

14 Jun 2022

Parental nicotine exposure may promote addiction-like behaviors in successive generations

Parental smoking is a significant risk factor for developing smoking behavior and nicotine dependence in offspring. These findings suggest that parental nicotine exposure may promote addiction-like behaviors in subsequent generations.

8 Jun 2022

Scientists propose a neurocomputational model of creative processes

"Many believe that creativity is assigned to a single brain region. But that is not the case," said Radwa Khalil. Together with scientists from South Africa and Australia, the neurobiologist at Jacobs University Bremen has proposed a computer-based model that assigns creative processes to neural networks in the brain.

3 Jun 2022

Study identifies how ketamine works as a rapid antidepressant

Ketamine is the speedster of antidepressants, working within hours compared to more common antidepressants that can take several weeks. But ketamine can only be given for a limited amount of time because of its many side effects.

1 Jun 2022

New imaging approach helps scientists build a complete picture of brain networks

Researchers at the Francis Crick Institute have developed an imaging technique to capture information about the structure and function of brain tissue at subcellular level – a few billionth of a metre, while also capturing information about the surrounding environment.

25 May 2022

Neuroscientists pinpoint brain mechanism responsible for common type of age-related memory loss

Working with rats, neuroscientists at Johns Hopkins University have pinpointed a mechanism in the brain responsible for a common type of age-related memory loss.

20 May 2022

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

The findings of a new pre-clinical study published in The Journal of Neuroscience are helping pave the way toward better understanding, prevention and recovery of neonatal brain injuries.

19 May 2022

Acoustic holograms enable efficient, selective opening of the blood brain barrier

The holograms designed by the team of researchers from UPV and CSIC allow the opening of the blood brain barrier selectively, efficiently and in a highly focused manner, facilitating the administration of therapeutic drugs to treat pathologies that affect the central nervous system.

17 May 2022

Targeting specific neurons modulates memory retrieval and alters anxiety-like behaviors in mice

We humans lose mental acuity, an unfortunate side effect of aging. And for individuals with neurodegenerative conditions such as Alzheimer's and Parkinson's, the loss of cognitive function often accompanied by mood disorders such as anxiety is a harrowing experience.

16 May 2022

Study finds link between hippocampal defects and intellectual disability in children with Joubert Syndrome

An important link has been found between the intellectual disability experienced by children with the rare disease Joubert Syndrome (JS) and defects in the hippocampus.

10 May 2022

Newly discovered brain circuit facilitates the ability to focus on what is important in the environment

When exploring a new environment, mice make use of a unique long-distance connection in the brain that prompts them to pay attention to the most salient features of the environment, according to new research from UC San Francisco. The link, originating in the prefrontal cortex and stretching to the hippocampus, provides evidence of how the brain's higher cognitive regions refine operations occurring in distant brain areas.

4 May 2022

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

During experiments in animal models, researchers at the University of Kansas have discovered a possible new approach to immunization against Alzheimer's disease (AD).

4 May 2022

New insights into the link between EMFs, calcium and Alzheimer’s disease

For almost a quarter of a century, researchers have been studying and publishing on the effect of calcium on Alzheimer's Disease. Research has led to the development of the calcium hypothesis of Alzheimer's disease, which argues that Alzheimer's is caused by excessive intracellular calcium.

26 Apr 2022

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Alzheimer's disease is marked by a loss of functional neurons in the brain. But what causes this loss? Through single-cell genome sequencing, researchers at Boston Children's Hospital, Brigham and Women's Hospital, and the Broad Institute show that people with Alzheimer's have an abundance of newly acquired mutations in their neurons - more than people of the same age without Alzheimer's, and enough to disable genes important to brain function.

20 Apr 2022

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

A little-studied enzyme has been found in high levels in healthy neurons, levels that scientists say decline with age and more dramatically with Alzheimer's, making adjusting the enzyme's level a potential treatment for both.

19 Apr 2022