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Researchers visualize antigen-bound T-cell receptor at atomic resolution

T cells are our immune system’s customized tools for fighting infectious diseases and tumor cells. On their surface, these special white blood cells carry a receptor that recognizes antigens.

18 Aug 2022

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands.

16 Aug 2022

Mechanism of vaccinia virus assembly in infected-cells

In a new study, researchers explored the driving factors of the vaccinia virus assembly across infected cells.

16 Aug 2022

What is the potential role of sphingosine kinase inhibitors as antiviral agents?

In a new study, researchers explored sphingosine kinases inhibitors and characterized the role of SKs in Ebola virus (EBOV) entry.

16 Aug 2022

In monkeys, spike-based vaccines produce some immunity based on CD8 T-cells

Scientists evaluate the role of CD8+ T-cells in vaccine protection against SARS-CoV-2 infection in rhesus macaques.

14 Aug 2022

How should we react to the global monkeypox outbreak?

In a new study, researchers assessed the various aspects of the global monkeypox outbreak.

12 Aug 2022

Researchers explore SARS-CoV-2 entry route and downstream cellular and viral processes

In a new study, researchers assessed the impact of the SARS-CoV-2 entry route on downstream cellular and viral processes.

10 Aug 2022

B-cell responses to COVID mRNA vaccine are enhanced by a 16-week interval between doses

Researchers assess the impact of extending the interval between primary and booster COVID-19 vaccine doses.

9 Aug 2022

Optically controlled local heat-pulse method manipulates temperature in cells

A team of researchers led by Osaka University finds that mutant variants of the calcium channel protein RyR1 are hypersensitive to heat, which creates a positive feedback loop of calcium release and leads to malignant hyperthermia

8 Aug 2022

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

5 Aug 2022

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.

3 Aug 2022

Novel algorithm provides rich, detailed information on protein location and function within a cell

Humans are good at looking at images and finding patterns or making comparisons. Look at a collection of dog photos, for example, and you can sort them by color, by ear size, by face shape, and so on. But could you compare them quantitatively? And perhaps more intriguingly, could a machine extract meaningful information from images that humans can't?

2 Aug 2022

Highly specialized T cells remain in blood 20 months after COVID-19

researchers analyze T-cell reactivity following recovery from COVID-19.

27 Jul 2022

Scientists explore SARS-CoV-2 spike protein and platelet-activating factor

Researchers assessed the association between platelet-activating factor (PAF) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein.

25 Jul 2022

Researchers investigate the feasibility of modifying cholera toxin for targeted delivery to specific organelles

Proteins usually undergo modifications during or after their synthesis in the endoplasmic reticulum (ER) and Golgi apparatus network inside eukaryotic cells.

25 Jul 2022

Oligomeric molecular structure of the MOR-Gal1R complex revealed

A study published in the journal Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids.

22 Jul 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Researchers evaluated the activity of nitazoxanide against human coronaviruses (HCoVs).

18 Jul 2022

Cytokine-based cancer immunotherapy: current progress and future prospects

In this interview, News-Medical talks to Dr. Shuang Zhou about cytokine-base cancer immunotherapy, the current state of the field, and future prospects.

From Sino Biological Inc. 18 Jul 2022

Unique tool helps to study how the mechanical forces behind protein folding affect cancer spread

Talin is a protein that controls cellular attachment and movement, but its malfunctioning also allows cancer cells to spread. DCL1 is a tumor-suppressing protein. But scientists don't fully understand how either protein works – or what happens when they don't work the way they should.

15 Jul 2022

Intracellular News and Research

Researchers visualize antigen-bound T-cell receptor at atomic resolution

Discovery explains how impaired metabolism triggers neuroendocrine tumors in the adrenal glands

Mechanism of vaccinia virus assembly in infected-cells

What is the potential role of sphingosine kinase inhibitors as antiviral agents?

In monkeys, spike-based vaccines produce some immunity based on CD8 T-cells

How should we react to the global monkeypox outbreak?

Researchers explore SARS-CoV-2 entry route and downstream cellular and viral processes

B-cell responses to COVID mRNA vaccine are enhanced by a 16-week interval between doses

Optically controlled local heat-pulse method manipulates temperature in cells

Researchers delve deeper into the structure of protein receptor crucial for cardiovascular health

Fruit fly genome contains whole genomes of a kind of bacteria, study finds

Novel algorithm provides rich, detailed information on protein location and function within a cell

Highly specialized T cells remain in blood 20 months after COVID-19

Scientists explore SARS-CoV-2 spike protein and platelet-activating factor

Researchers investigate the feasibility of modifying cholera toxin for targeted delivery to specific organelles

Oligomeric molecular structure of the MOR-Gal1R complex revealed

Is monkeypox a global public-health emergency?

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Cytokine-based cancer immunotherapy: current progress and future prospects

Unique tool helps to study how the mechanical forces behind protein folding affect cancer spread

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