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Identifying Alport syndrome in children through universal age-3 urine screening

The most common first diagnosis of Alport syndrome in Japan is during the universal age-3 urine screening.

7 Oct 2025

NCCN enhances widely used breast cancer guidelines with advanced digital features

Today, the National Comprehensive Cancer Network® (NCCN®)-a nonprofit responsible for globally utilized guidelines for cancer care-is sharing new NCCN Guidelines Navigator™ resources for breast cancer treatment as well as genetic/familial high-risk assessment, during Breast Cancer Awareness Month.

7 Oct 2025

FDA grants approval to begin Phase I clinical trials of heart tissue regeneration drug AD-NP1

The body's tissues can get injured in many ways, but while some injuries heal perfectly, others don't heal at all. A cut in the skin, for example, usually heals all on its own, while internal organs, such as the heart after a heart attack or the kidney after an acute injury, remain damaged, leading to diminished function.

6 Oct 2025

Enzyme technology enables first successful blood type conversion in kidney transplant

The first successful human transplant of a kidney converted from blood type A to universal type O used special enzymes developed at the University of British Columbia to help prevent a mismatch and rejection of the organ.

3 Oct 2025

New tool enables and enhances protein investigations

A new tool greatly improves scientists' ability to identify and study proteins that regulate gene activity in cells, according to research led by Weill Cornell Medicine investigators. The technology should enable and enhance investigations in both fundamental biology and disease research.

3 Oct 2025

New protein map could improve diagnosis and understanding of rare ciliopathies

Attached to nearly every human cell is an antenna-like structure known as the primary cilium, which senses the cell's environment and controls how it responds to signals from its surroundings.

3 Oct 2025

Discovery reveals hidden differences in herpes virus cultures

Matthew Taylor likened his recently published work alongside doctoral student Gary Dunn to kicking over a rock. Once the discovery was made, it was time to see what lay beneath.

3 Oct 2025

Stem cells and organoids offer a new understanding of APOL1 kidney disease

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for CKD include mutations in a gene called APOL1.

3 Oct 2025

Restoring delta cell function may prevent dangerous hypoglycemic events in diabetes

A new study by the University of California, Davis, shows how cells work together to avoid a sudden drop in blood sugar. Understanding these feedback loops could improve the lives of people with diabetes and help them avoid dangerous hypoglycemia.

3 Oct 2025

Inactive blood marker SDMA emerges as potential predictor of cardiovascular risk in CKD

When University of Texas at Arlington researcher Paul J. Fadel and his colleagues launched a study on vascular health in people with chronic kidney disease, they expected to better understand a long-standing belief.

3 Oct 2025

Study finds limited value of CGM data for non-diabetic individuals

Continuous glucose monitors (CGMs) are wearable technologies that track blood sugar in real time and help patients with type 2 diabetes improve blood sugar control.

2 Oct 2025

Shift workers face higher risk of developing kidney stones

A study evaluating how various shift work patterns contribute to kidney stone risk has revealed that shift workers have a 15% higher risk of developing kidney stones, especially younger workers and those with low levels of manual labor.

2 Oct 2025

Prediabetes can go into remission without weight loss

Research shows up to 22% of prediabetic individuals achieve remission without weight loss, emphasizing metabolic health over weight loss in diabetes prevention.

2 Oct 2025

Genetic risk scores fail to predict survival after diagnosis

Research indicates that disease susceptibility genetics poorly predict survival, while longevity PGSs offer stronger associations with post-diagnosis mortality.

2 Oct 2025

Study shows prediabetes remission does not always require weight loss

Remission of prediabetes can occur even without weight loss, protecting against type 2 diabetes in up to 22% of individuals. Metabolic improvements, healthier fat distribution, and enhanced β-cell function, not body weight change, drive this benefit.

30 Sep 2025

Inflammation at the heart’s core: What clinicians and families can do now

Chronic low-grade inflammation is a key driver of cardiovascular disease, even when cholesterol is controlled. The ACC’s 2025 Scientific Statement highlights hsCRP as a routine risk marker and outlines lifestyle and pharmacologic anti-inflammatory strategies for prevention and treatment.

30 Sep 2025

Undiagnosed G6PD deficiency can lead to delayed diabetes diagnosis for Black and Asian men

A common but often undiagnosed genetic condition may be causing delays in type 2 diabetes diagnoses and increasing the risk of serious complications for thousands of Black and South Asian men in the UK - and potentially millions worldwide.

30 Sep 2025

Myo-inositol fails to lower pregnancy risks in women with PCOS

Myo-inositol supplementation shows no significant benefits in preventing pregnancy complications for women with PCOS, according to a recent large-scale study.

30 Sep 2025

Yale researchers develop new test for early leptospirosis detection

In a new study, Yale School of Medicine (YSM) researchers unveiled a novel diagnostic method for detecting leptospiral virulence-modifying (VM) proteins in the blood and urine of hamsters, an advance that could pave the way for early diagnosis of the tropical disease leptospirosis in humans and improved treatment options.

29 Sep 2025

New mRNA vaccine stops allergens from causing life-threatening inflammation in mice

A new mRNA vaccine stopped allergens from causing dangerous immune reactions and life-threatening inflammation in mice, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Cincinnati Children's.

29 Sep 2025