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Common nerve pain drugs may set off prescribing cascades in older patients

Clinicians may fail to recognize common side effects of drugs like gabapentin - which are frequently prescribed for nerve pain - leading them to prescribe unnecessary medications that cause yet more side effects.

2 Dec 2025

WHO releases first guideline on the use of GLP-1 therapies for treating obesity

To address the growing global health challenge of obesity, which affects more than 1 billion people, the World Health Organization (WHO) has released its first guideline on the use of Glucagon-Like Peptide-1 (GLP-1) therapies for treating obesity as a chronic, relapsing disease.

2 Dec 2025

Why green tea delivers the strongest health benefits

This review examines tea's health effects, highlighting green tea's benefits for heart health and cognition, and warns about risks in processed tea products.

1 Dec 2025

Music therapy speeds anesthesia recovery in colorectal surgery

Integrating music therapy with anesthesia recovery care enhances recovery in colorectal cancer patients, reducing complications and stabilizing vital signs.

28 Nov 2025

New 10-minute scan shows hidden cause of high blood pressure

A speedy new scan could improve how millions of people with high blood pressure are treated, suggests a new study led by UCL (University College London) researchers.

26 Nov 2025

UBC researchers reveal how statins trigger muscle damage

Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes.

26 Nov 2025

'Myeloid mimicry' identified as driver of immunotherapy resistance in renal medullary carcinoma

Researchers at The University of Texas MD Anderson Cancer Center have found that renal medullary carcinoma (RMC) cells use an adaptive mechanism called "myeloid mimicry" to hide from the immune system and promote disease hyper progression after immunotherapy, highlighting specific targets that overcome treatment resistance in preclinical models.

25 Nov 2025

Retrospective analysis shows mortality rates and risk factors after prosthetic heart valve surgeries

Mechanical valve replacement is a primary treatment for rheumatic heart disease, yet prosthesis-related adverse outcomes remain underreported in India.

25 Nov 2025

Culturally tailored intervention helps reduce interdialytic weight gain in kidney failure care

The intervention, called Navigate-Kidney, utilizes community health workers (CHWs) to help patients undergoing hemodialysis understand and work through challenges that come with treatment, including socioeconomic factors, particularly food insecurity as well as lack of culturally responsive care, and disparities in access to health insurance and health care.

24 Nov 2025

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.

24 Nov 2025

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

Inflammation control can protect against AMD-like retinal damage

University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models.

21 Nov 2025

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

The liver plays a central role in storing and supplying energy to the body. In type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD, commonly referred to as fatty liver disease), mitochondria-the cell's power plants-cannot switch efficiently between fuel sources.

21 Nov 2025

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

GLP-1 receptor agonists improve glycaemic control and provide renal, metabolic, and selective cardiovascular benefits in people with type 2 diabetes, based on an umbrella review of 17 meta-analyses. However, these agents consistently increase gastrointestinal adverse effects and show important distinctions between class-level outcomes and individual drug effects, particularly for semaglutide.

20 Nov 2025

Study develops highly accurate polygenic risk models tailored for Han Chinese populations

Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders.

20 Nov 2025

Study compares the kidney, cardiovascular and mortality risks of three different GLP-1 RAs

Public interest in drugs known as glucagon-like peptide-1 receptor agonists, also called GLP-1 RAs, has surged in recent years, with popular types like semaglutide (sold under brand names like Ozempic and Wegovy) becoming known for their weight-loss effects.

20 Nov 2025

A hidden health crisis following natural disasters: Mold growth in homes

After returning from what felt like the best internship of her life, Danae Daniels was excited to unwind and settle into a new semester at Florida Agricultural and Mechanical University.

19 Nov 2025

Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

Oral semaglutide delivered meaningful reductions in HbA1c and body weight among GLP-1RA-naïve adults with type 2 diabetes in a Dutch real-world cohort. Lipid levels and blood pressure showed only small changes, reflecting modest cardiometabolic effects outside glucose and weight control.

18 Nov 2025

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading to dialysis in advanced cases.

18 Nov 2025

Study links obesity severity to escalating cardiometabolic and renal disease burden

Obesity severity is incrementally associated with a broad range of cardiometabolic and renal disease burden, as discovered by researchers at Pennington Biomedical Research Center. Recently published in Obesity, the paper "Association of Obesity Severity with Cardiometabolic and Renal Disease Burden in the United States," explored the relationship through a cross-sectional study of data from the U.S. Behavioral Risk Factor Surveillance System survey.

18 Nov 2025

Kidney News and Research

Common nerve pain drugs may set off prescribing cascades in older patients

WHO releases first guideline on the use of GLP-1 therapies for treating obesity

Why green tea delivers the strongest health benefits

Music therapy speeds anesthesia recovery in colorectal surgery

New 10-minute scan shows hidden cause of high blood pressure

UBC researchers reveal how statins trigger muscle damage

'Myeloid mimicry' identified as driver of immunotherapy resistance in renal medullary carcinoma

Retrospective analysis shows mortality rates and risk factors after prosthetic heart valve surgeries

Culturally tailored intervention helps reduce interdialytic weight gain in kidney failure care

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Inflammation control can protect against AMD-like retinal damage

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

Study develops highly accurate polygenic risk models tailored for Han Chinese populations

Study compares the kidney, cardiovascular and mortality risks of three different GLP-1 RAs

A hidden health crisis following natural disasters: Mold growth in homes

Oral semaglutide delivers real-world drops in blood sugar and weight in diabetes trial

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Study links obesity severity to escalating cardiometabolic and renal disease burden

Event guide: 8th CKD Summit 2026 eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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