Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Study identifies subgroups of patients with distinct, persistent pain after breast cancer surgery

Some 25 percent of breast cancer surgery patients experience significant, persistent pain six months after the procedure, and new research published in The Journal of Pain showed that women with preoperative breast pain have the highest risk for extended post-surgical pain.

17 Jan 2013

Partin Tables to predict prostate cancer spread now updated

Prostate cancer experts at Johns Hopkins have developed an updated version of the Partin Tables, a tool to help men diagnosed with prostate cancer and their doctors to better assess their chance of a surgical cure. The updated tool, based on a study of more than 5,600 men treated at The Johns Hopkins Hospital from 2006 to 2011, is published in the Jan. 3 issue of the British Journal of Urology International.

3 Jan 2013

18F-FDG PET/CT may become important distant staging modality in patients with breast cancer

New research published in the January issue of The Journal of Nuclear Medicine shows that 18F-fludeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging offers significant prognostic stratification information at initial staging for patients with locally advanced breast cancer. When compared to conventional imaging, 18F-FDG PET/CT more accurately showed lesions in the chest, abdomen and bones in a single session, changing management for more than 50 percent of the patients in the study.

3 Jan 2013

Personalized rectal cancer therapy shows promise

Personalized chemotherapy for rectal cancer results in high rates of pathologic response, indicate the results of a pilot study.

19 Dec 2012

Enlarged lymph nodes may warn of cancer

Enlarged lymph nodes are a marker for both occult cancer and a long-term risk for malignancy, confirms research published in the British Journal of Haematology.

19 Dec 2012

Predictor of lymph node metastasis after oral cancer unmasked

The presence of high levels of tumor-associated tissue eosinophilia in early oral squamous cell carcinoma tissue can predict future occult lymph node metastasis, study results show.

13 Dec 2012

Celgene announces results from REVLIMID plus VIDAZA phase II study on AML

Celgene International Sàrl today announced that results from a study evaluating the combination of REVLIMID (lenalidomide) plus VIDAZA (azacitidine) in patients 60 years or older with untreated acute myeloid leukemia (AML) were presented at the American Society of Hematology annual meeting in Atlanta, GA.

11 Dec 2012

Ibrutinib may effectively combat chronic lymphocytic leukemia

The promising investigational targeted therapy ibrutinib and its mechanism of silencing gene communication pathways critical to the development of cancer may be an effective way to combat chronic lymphocytic leukemia (CLL), according to studies presented today at the 54th Annual Meeting of the American Society of Hematology (ASH).

10 Dec 2012

Research Roundup: Medicare Advantage Plan beneficiaries may get more appropriate use of services; CHIP participation grows; College students' flu vaccination rates weak

Analysis Of Medicare Advantage HMOs Compared With Traditional Medicare Shows Lower Use of Many Services During 2003-09 – Researchers compared the utilization rates of Medicare Advantage health maintenance organizations (HMOs) with those of traditional Medicare beneficiaries, 2003-09, "to ascertain whether the HMO enrollees demonstrated different levels of use of services, which can be a hallmark of more integrated care."

7 Dec 2012

SLN surgery identifies whether breast cancer in lymph nodes remains after chemotherapy

Most patients whose breast cancer has spread to their lymph nodes have most of the lymph nodes in their armpit area removed after chemotherapy to see if any cancer remains. A study conducted through the American College of Surgeons Oncology Group and led by Judy Boughey, M.D. a breast surgeon at Mayo Clinic shows that a less invasive procedure known as sentinel lymph node surgery successfully identified whether cancer remained in lymph nodes in 91 percent of patients with node-positive breast cancer who received chemotherapy before their surgery.

6 Dec 2012

African American women less likely to receive axillary SLN biopsy for breast cancer

African American women with early stage, invasive breast cancer were 12 percent less likely than Caucasian women with the same diagnosis to receive a minimally invasive technique, axillary sentinel lymph node (SLN) biopsy, years after the procedure had become the standard of surgical practice, according to research from The University of Texas MD Anderson Cancer Center.

6 Dec 2012

Studies show possibility of improving healthcare by tackling problem in standardized way

Given the right equipment, training and skill, an individual surgeon can expect to provide the best possible care on a consistent basis.

1 Dec 2012

Ultrasound-guided transbronchial needle aspiration complication rate ‘reassuring’

Multisite findings support the use of endobronchial ultrasound-guided transbronchial needle aspiration for mediastinal lymph node sampling.

12 Nov 2012

Mastoscopic axillary lymph node dissection ‘preferred choice’

Long-term study findings support the use of mastoscopic axillary lymph node dissection for women with operable breast cancer.

12 Nov 2012

Radiotherapy protocol deviations: an interview with Dr Nitin Ohri

Radiotherapy is a key component of cancer therapy. A majority of cancer patients get radiotherapy in some form at some point in their disease course. It can be used in a curative setting or in a palliative setting.

12 Nov 2012

Mastoscopic axillary lymph node dissection can reduce breast cancer complications

Axillary lymph node dissection is done in conjunction with lumpectomy or mastectomy to determine if breast cancer has spread to the adjoining lymph nodes. The conventional surgical approach leaves a surgical scar that is unattractive and can restrict range of motion in the shoulder joint. Also, squeezing and pulling the tumor during the breast operation can stimulate tumor cell metastases.

9 Nov 2012

Surgical features determine survival in radical prostatectomy patients

The impact of adjuvant radiotherapy on cancer-specific mortality and overall mortality rates in patients who have undergone radical prostatectomy depends on the cumulative number of certain pathologic features found during surgery, report researchers.

5 Nov 2012

First study to measure minute changes in breast tumor connective tissue fibers

Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread.

3 Nov 2012

Elderly women with early-stage breast cancer live longer with radiation therapy and surgery

Elderly women with early-stage breast cancer live longer with radiation therapy and surgery compared with surgery alone, researchers at the University of Maryland School of Medicine have found.

30 Oct 2012

Rectal cancer more likely to spread to the lymph nodes in younger patients

Rectal cancer is more likely to spread to the lymph nodes in younger patients, according to new findings that Fox Chase Cancer Center researchers will be presenting on October 29 at the American Society for Radiation Oncology's 54th Annual Meeting.

29 Oct 2012

Lymph Node News and Research

Further Reading

Study identifies subgroups of patients with distinct, persistent pain after breast cancer surgery

Partin Tables to predict prostate cancer spread now updated

18F-FDG PET/CT may become important distant staging modality in patients with breast cancer

Personalized rectal cancer therapy shows promise

Enlarged lymph nodes may warn of cancer

Predictor of lymph node metastasis after oral cancer unmasked

Celgene announces results from REVLIMID plus VIDAZA phase II study on AML

Ibrutinib may effectively combat chronic lymphocytic leukemia

Research Roundup: Medicare Advantage Plan beneficiaries may get more appropriate use of services; CHIP participation grows; College students' flu vaccination rates weak

SLN surgery identifies whether breast cancer in lymph nodes remains after chemotherapy

African American women less likely to receive axillary SLN biopsy for breast cancer

Studies show possibility of improving healthcare by tackling problem in standardized way

Ultrasound-guided transbronchial needle aspiration complication rate ‘reassuring’

Mastoscopic axillary lymph node dissection ‘preferred choice’

Radiotherapy protocol deviations: an interview with Dr Nitin Ohri

Mastoscopic axillary lymph node dissection can reduce breast cancer complications

Surgical features determine survival in radical prostatectomy patients

First study to measure minute changes in breast tumor connective tissue fibers

Elderly women with early-stage breast cancer live longer with radiation therapy and surgery

Rectal cancer more likely to spread to the lymph nodes in younger patients

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