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Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Researchers studied open and closed conformations of the C-terminal of SARS-CoV-2 nucleocapsid (N) protein termed the NCTD.

19 Jul 2022

Scientists manipulate good bacteria using CRISPR systems

New North Carolina State University research shows progress in gathering information on an important – yet difficult to characterize – human gut bacterium called Bifidobacterium, which is used in many probiotics that help maintain healthy microbiomes.

19 Jul 2022

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

In a new study, researchers uncovered distinct genomic features of SARS-CoV-2 Delta and Omicron variants.

13 Jul 2022

Researchers conduct forensic analysis of SARS-CoV-2-related coronaviruses

Researchers conducted a forensic analysis of SARS-CoV-2-related coronaviruses (SARS2r-CoVs).

13 Jul 2022

Evolutionary characteristics of the SARS-CoV-2 Omicron variant

Researchers compared the mutations in the SARS-CoV-2 Omicron variant with others to highlight their evolutionary differences.

13 Jul 2022

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

Researchers assessed the impact of the vaccinia virus vaccine on the immune response against the monkeypox virus.

12 Jul 2022

The impact of gene amplification in virus adaptation through intermediate hosts

Researchers assessed the impact of gene amplification on cross-species adaptation.

12 Jul 2022

Early detection of SARS-CoV-2 variants via wastewater sequencing uncovers cryptic transmission

In a recent study published in the Nature journal, researchers assessed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission using wastewater sequencing.

11 Jul 2022

Scientists identify molecules promoting plant immunity

Two studies published by researchers at the Max Planck Institute for Plant Breeding Research in Cologne, Germany in collaboration with colleagues in China have discovered natural cellular molecules that drive critical plant immune responses.

7 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

SARS-Cov-2 Omicron variant raises significant concerns about high transmissibility in China

Omicron (B.1.1.529), the fifth variant of concern (VOC) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was firstly identified in November 2021 in South Africa. Omicron contains far more genome mutations than any other VOCs ever found, raising significant concerns about its increased transmissibility and immune evasion.

5 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Researchers performed genomic comparisons between alphacoronaviruses (αCoVs) and betacoronaviruses (βCoVs) originating from South Korean Bats.

28 Jun 2022

Evolution of SARS-CoV-2 genomes based on continuing positive selection

Researchers hypothesized that ongoing positive selection strongly influences SARS-CoV-2 genomes, which plays an important role in shaping the dynamics of the COVID-19 pandemic.

28 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

Nucleotide News and Research

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Scientists manipulate good bacteria using CRISPR systems

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

Researchers conduct forensic analysis of SARS-CoV-2-related coronaviruses

Evolutionary characteristics of the SARS-CoV-2 Omicron variant

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

The impact of gene amplification in virus adaptation through intermediate hosts

Early detection of SARS-CoV-2 variants via wastewater sequencing uncovers cryptic transmission

Scientists identify molecules promoting plant immunity

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

SARS-Cov-2 Omicron variant raises significant concerns about high transmissibility in China

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Evolution of SARS-CoV-2 genomes based on continuing positive selection

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

Comparison of genome sequences of SARS-CoV-2 and other coronaviruses

Mapping the trajectory of SARS-CoV-2 evolution inside the host

"Founder events" that reduced genetic diversity found to be common throughout human history

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Gene expression regulation by N6-methyladenosine

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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