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Dapagliflozin and calorie restriction show higher remission rates in type 2 diabetes

Adults with overweight or obesity and type 2 diabetes who are given the sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin alongside moderate calorie restriction achieve much higher rates of remission compared with calorie restriction alone, finds a trial published by The BMJ today.

23 Jan 2025

New Factor XI inhibitor shows superior safety in treating atrial fibrillation

Patients with atrial fibrillation are typically prescribed an anticoagulant, or blood thinner, to reduce the risk of stroke, but many may discontinue them or never receive a prescription due to concerns of increased risk of bleeding complications.

22 Jan 2025

Electroacupuncture may aid in personalized ribavirin dosing for long COVID

Various devices are used to study the unique electrical properties of acupuncture points (APs), with Voll's electropuncture diagnostics (EAV) occupying a prominent role.

21 Jan 2025

Groundbreaking trial finds levofloxacin effective against multidrug-resistant TB

A clinical trial published in the New England Journal of Medicine showed that the oral antibiotic levofloxacin taken once-daily for six months substantially reduced the risk of developing drug-resistant tuberculosis (TB), and almost halved adults' and children's risk of developing multidrug-resistant TB.

15 Jan 2025

Semaglutide improves glycemic control with automated insulin delivery

Semaglutide combined with automated insulin delivery enhances glucose control in type 1 diabetes, lowering insulin requirements and aiding weight management.

15 Jan 2025

Hebrew SeniorLife launches trial to explore probiotics and prebiotics for bone health

Hinda and Arthur Marcus Institute for Aging Research investigators at Hebrew SeniorLife have launched a large clinical food trial to test whether a combination of probiotics and prebiotics (BondiaÒ or SBD111) developed by Solarea Bio will help manage bone health in women aged 60 years and above.

10 Jan 2025

Elderberry juice shows promise in boosting gut health and combating obesity

Elderberry juice rich in anthocyanins boosts glucose regulation and fat metabolism, with significant effects on gut microbiota in overweight adults.

10 Jan 2025

Hormonal changes after menopause impact multiple sclerosis severity

A new study by UC San Francisco has found that menopause revs up the progression of multiple sclerosis (MS).

10 Jan 2025

Elderberry juice improves metabolic health and weight management

Elderberry juice may be a potent tool for weight management and enhancing metabolic health, according to a recent Washington State University-led study.

8 Jan 2025

Single-dose malaria vaccine offers unprecedented 90% protection

Results from the malaria vaccine trial indicate that GA2 immunization provides significant protection, paving the way for more effective vaccination strategies.

8 Jan 2025

AI-designed drug shows promise for inflammatory bowel disease

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announces positive results from two Phase I studies in Australia and China of ISM5411, a novel gut-restricted and PHD specific Inhibitor designed and optimized with the support of Insilico's Chemistry42 commercially-available generative reinforcement learning platform, for Inflammatory Bowel Disease (IBD).

8 Jan 2025

Psilocybin shows potential for treating mental health disorders in people with cancer and addiction

One or two doses of psilocybin, a compound found in psychedelic mushrooms, may improve the mental health of cancer patients when accompanied by psychotherapy, a new report suggests.

2 Jan 2025

New migraine drug atogepant shows quick relief

A drug recently approved to prevent migraine may start working right away, according to a study published in the December 23, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

23 Dec 2024

Propranolol helps control Parkinson's tremors

The standard medication levodopa does not always work against tremors in Parkinson's disease, especially in stressful situations.

23 Dec 2024

Comprehensive study highlights effectiveness and limitations of ADHD treatments in adults

Findings indicate stimulants and atomoxetine effectively reduce ADHD symptoms, though non-pharmacological therapies show potential for long-term efficacy.

20 Dec 2024

Nogo-A inhibition demonstrates potential for spinal cord injury recovery

The latest study results have been published online in the renowned "The Lancet Neurology" journal. A multi-centre clinical trial (NISCI trial: Nogo-A Inhibition in acute Spinal Cord Injury Study) investigated the antibody NG 101 (anti-Nogo-A), which blocks and thus neutralizes the body's own Nogo-A protein.

19 Dec 2024

Combining psychedelics with meditation increases mindfulness and mystical-type transcendence

Researchers assessed whether combining psychedelics, namely DMT and harmine as two active ingredients in ayahuasca, with meditation increases mindfulness, compassion, insight, and mystical-type transcendence to a higher degree than meditation with a placebo.

19 Dec 2024

Can probiotics restore antibiotic-perturbed microbiota?

Probiotics can reduce antibiotic-associated diarrhea but don't fully restore gut microbiota. Further studies are essential to evaluate their long-term effects.

19 Dec 2024

CBD can be used safely in women with advanced breast cancer and clinical anxiety

This Phase II trial explores CBD for anxiety in breast cancer patients, indicating safety and potential anxiolytic effects despite no primary outcome success.

18 Dec 2024

Pioneering study shows promising results for cognitive treatment in Down syndrome

The ICOD (Improving Condition in Down syndrome) project, a pioneering study in addressing the cognitive difficulties associated with Down syndrome, has demonstrated the safety of treatment with the molecule AEF0217, developed by the French biotech Aelis Farma, as well as its effectiveness in improving cognitive function in these people.

17 Dec 2024

Placebo News and Research

Dapagliflozin and calorie restriction show higher remission rates in type 2 diabetes

New Factor XI inhibitor shows superior safety in treating atrial fibrillation

Electroacupuncture may aid in personalized ribavirin dosing for long COVID

Groundbreaking trial finds levofloxacin effective against multidrug-resistant TB

Semaglutide improves glycemic control with automated insulin delivery

Hebrew SeniorLife launches trial to explore probiotics and prebiotics for bone health

Elderberry juice shows promise in boosting gut health and combating obesity

Hormonal changes after menopause impact multiple sclerosis severity

Elderberry juice improves metabolic health and weight management

Single-dose malaria vaccine offers unprecedented 90% protection

AI-designed drug shows promise for inflammatory bowel disease

Psilocybin shows potential for treating mental health disorders in people with cancer and addiction

New migraine drug atogepant shows quick relief

Propranolol helps control Parkinson's tremors

Comprehensive study highlights effectiveness and limitations of ADHD treatments in adults

Nogo-A inhibition demonstrates potential for spinal cord injury recovery

Combining psychedelics with meditation increases mindfulness and mystical-type transcendence

Can probiotics restore antibiotic-perturbed microbiota?

CBD can be used safely in women with advanced breast cancer and clinical anxiety

Pioneering study shows promising results for cognitive treatment in Down syndrome

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