Therapeutics News and Research

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Researchers discover new therapeutic target for rare, aggressive pediatric cancers

Researchers at The University of Texas MD Anderson Cancer Center have discovered that malignant rhabdoid tumors, a rare pediatric cancer without effective treatments, may be sensitive to drugs that block the cancer cell's ability to dispose of misfolded proteins.

12 Feb 2019

Marijuana edibles carry risk and side effects for patients with cardiovascular disease

As marijuana legalization sweeps North America, use of the substance has been on the rise, and the public's attitude is shifting. An increasing number of people believe that "weed" is the safest recreational drug, one that carries health benefits that outweigh its risks.

11 Feb 2019

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.

11 Feb 2019

New measurable indicator could prove instrumental in fight against HIV

George Mason University's Yuntao Wu is the lead scientist on a research team that has identified a measurable indicator that could prove instrumental in the fight against HIV.

11 Feb 2019

Scientists create 3D-bioprinted brain model to study interaction with immune cells

Around a glioblastoma, a very aggressive brain tumor, cells of the human immune system start helping the tumor instead of attacking it. To do research on what happens in the interaction of these cells, scientists of the University of Twente now created a 3D-bioprinted mini model of the brain.

11 Feb 2019

IDT supports innovative synthetic biology start-ups with grant program

Integrated DNA Technologies’ Synthetic Biology Start-up Grant Program has once again benefited innovative start-ups in their missions to impact sustainable manufacturing, human health, and/or humanitarian causes.

From Integrated DNA Technologies 8 Feb 2019

Researchers find anti-microRNAs as potential new therapeutic target for type 2 diabetes

Researchers have shown that targeted silencing of microRNA-132, which is over-expressed in type 2 diabetes, can result in improved insulin secretion and reduced blood glucose in mice and increased insulin secretion in isolated human islet cells.

8 Feb 2019

Study shows precision medicines could aid more breast cancer patients via RNA-targeting

When women or men receive the worrisome diagnosis of breast cancer, that news comes with an important piece of information, namely, whether their cancer is HER2-positive or HER2-negative.

8 Feb 2019

Study uncovers how lung tissue remodels to support immune response to influenza

Immunology researchers at the Babraham Institute have discovered how lung tissue in mice is remodelled in response to infection with influenza in order to support an immune system response.

6 Feb 2019

New research uncovers crucial link between polyamines and MYCN

The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumor cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer.

4 Feb 2019

RNA-binding protein needed for development of pathological hypertrophy

In response to conditions such as high blood pressure and reduced blood flow to cardiac muscle, the adult heart can drastically enlarge, a process called pathological hypertrophy that preserves cardiac function in the short term but predisposes patients to intractable heart failure and sudden cardiac death if left untreated.

31 Jan 2019

FSU study breaks new ground in the battle against malignant pediatric brain cancers

Scientists are making important progress in the battle against a class of devilishly complex human pediatric brain cancers thanks to a new study from a team of Florida State University students and faculty.

30 Jan 2019

Study shows that aging and chronic diseases share common genetic factors

The global population aged 60 or over is growing faster than all younger age groups and faces the tide of chronic diseases threatening their quality of life and posing challenges to healthcare and economy systems.

30 Jan 2019

New study analyzes health outcomes of switching patients from analog to human insulin

In the United States, the drug price for insulin has skyrocketed over the last two decades. While the price has increased for all forms of insulin, newer, "analog" insulin medications such as glargine and lispro have become especially expensive.

30 Jan 2019

Researchers identify effects of nanoparticles on intestinal microorganisms

The intestinal microbiome is not only key for food processing but an accepted codeterminant for various diseases. Researchers led by the University Medical Center of Johannes Gutenberg University Mainz identified effects of nanoparticles on intestinal microorganisms.

29 Jan 2019

Researchers identify effects of nanoparticles on intestinal microorganisms

The intestinal microbiome is not only key for food processing but an accepted co-determinant for various diseases. Researchers led by the University Medical Center of Johannes Gutenberg University Mainz identified effects of nanoparticles on intestinal microorganisms.

29 Jan 2019

Stand Up To Cancer creates Dream Team focused on finding therapies for T-cell lymphoma

Stand Up To Cancer announced here today the creation of an $8 million Dream Team of top scientists focused on finding therapies for T-cell lymphoma, a rare cancer of the blood and immune system, using chimeric antigen receptors (CARs) to trigger the immune system to attack and destroy cancerous cells.

29 Jan 2019

New drug compounds show promise in treating acute myeloid leukemia

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year, and about 10,670 people a year die from it, according to the American Cancer Society.

29 Jan 2019

Annual RegenMed SA Conference to focus on future of stem cells

Doctors regularly perform stem cell transplants, also known as bone marrow transplants, to replace cells damaged by chemotherapy.

29 Jan 2019

New class of antisense oligonucleotide therapeutics tested in humans

A first-in-human study with a new class of antisense oligonucleotide therapeutics showed the ability to target the RNA-silencing drug to the liver, resulting in improved potency and safety at therapeutic doses. The design and results of this trial, conducted in healthy human volunteers are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Jan 2019

Therapeutics News and Research

Researchers discover new therapeutic target for rare, aggressive pediatric cancers

Marijuana edibles carry risk and side effects for patients with cardiovascular disease

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

New measurable indicator could prove instrumental in fight against HIV

Scientists create 3D-bioprinted brain model to study interaction with immune cells

IDT supports innovative synthetic biology start-ups with grant program

Researchers find anti-microRNAs as potential new therapeutic target for type 2 diabetes

Study shows precision medicines could aid more breast cancer patients via RNA-targeting

Study uncovers how lung tissue remodels to support immune response to influenza

New research uncovers crucial link between polyamines and MYCN

RNA-binding protein needed for development of pathological hypertrophy

FSU study breaks new ground in the battle against malignant pediatric brain cancers

Study shows that aging and chronic diseases share common genetic factors

New study analyzes health outcomes of switching patients from analog to human insulin

Researchers identify effects of nanoparticles on intestinal microorganisms

Researchers identify effects of nanoparticles on intestinal microorganisms

Stand Up To Cancer creates Dream Team focused on finding therapies for T-cell lymphoma

New drug compounds show promise in treating acute myeloid leukemia

Annual RegenMed SA Conference to focus on future of stem cells

New class of antisense oligonucleotide therapeutics tested in humans

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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