Therapeutics News and Research

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C-Path, CHDI and CDISC announce availability of Huntington's Disease Therapeutic Area User Guide

The Huntington's Disease Regulatory Science Consortium, launched in March 2018 by the Critical Path Institute and CHDI Foundation, today, along with the Clinical Data Interchange Standards Consortium, announce the open availability of a newly developed Huntington's Disease Therapeutic Area User Guide

2 Nov 2018

Researchers for first time view serotonin activating its receptor using high-powered microscopes

Serotonin receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders yet little is known about their three-dimensional structure.

2 Nov 2018

Integral Molecular wins NIH grant to initiate target discovery program for Alzheimer’s disease

Integral Molecular, the industry leader in membrane protein technologies, was awarded a Small Business Innovation Research grant from the NIH to initiate a target discovery program for Alzheimer's disease.

1 Nov 2018

Phase 2 study of ziresovir for treating hospitalized RSV infected infants achieves significant progress

Ark Biosciences, a biotech company developing proprietary therapeutics for viral infection and respiratory diseases, announced today the significant progress in its phase 2 proof-of-concept study of ziresovir in the treatment of hospitalized RSV infected infants.

1 Nov 2018

Researchers develop new strategy in the search for psychoactive drugs

Researchers at the University of Zurich and Harvard University have developed a new strategy in the search for psychoactive drugs.

1 Nov 2018

IU Philanthropic Venture Fund commits to invest $500,000 to NERx Biosciences company

The Indiana University Philanthropic Venture Fund, which provides capital to faculty, students, alumni and staff at all IU campuses to help them further develop their research and innovations into startup companies, has committed to invest $500,000 in Indianapolis-based NERx Biosciences Inc. as part of a $2.2 million bridge round.

1 Nov 2018

UC Scientist receives NIH grant for developing new malaria therapeutic strategies

A scientist at the University of California, Riverside, who researches the malaria-causing parasite, Plasmodium falciparum, is the principal investigator, or PI, on two grants from the National Institutes of Health, or NIH, totaling nearly $6.6 million. Funding from each grant is for five years.

1 Nov 2018

Celprogen successfully prints 3D Brains from brain stem cells to study neurological disease stages

Celprogen Inc., a leader in the Stem Cell Research and Therapeutics industry for stem cell research since 2002, today announced that they have successfully finished printing 3D Brains from brain stem cells for studying neurological disease stages.

1 Nov 2018

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

A cancer therapy based on fusing two types of cells into a single unit shows promise in strengthening existing treatments for acute myeloid leukemia. The approach joins blood platelets that carry cancer drugs with stem cells that guide the platelets into bone marrow where leukemia begins.

31 Oct 2018

Study: Single protein regulates network of genes essential for sperm development

A single protein regulates a battery of key genes inside developing sperm, according to a new study out of Case Western Reserve University School of Medicine.

31 Oct 2018

New City of Hope CAR T cell trial focuses on HER2-positive breast cancer patients with brain metastases

Women with HER2-positive breast cancer that has spread to the brain need more treatment options, and City of Hope and Mustang Bio Inc. are meeting that challenge.

30 Oct 2018

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Delivering an effective therapeutic payload to specific target cells with few adverse effects is considered by many to be the holy grail of medical research. A new Tel Aviv University study explores a biological approach to directing nanocarriers loaded with protein "game changers" to specific cells.

30 Oct 2018

Neuroene Therapeutics receives $1.5 million NIH grant to develop anti-seizure compound for epilepsy

Neuroene Therapeutics, a start-up company founded by mitochondrial biologist Sherine S. L. Chan, Ph.D. and medicinal chemist C. James Chou, Ph.D. of the Medical University of South Carolina, has received a $1.5 million NIH Phase II Small Business Innovation Research grant to optimize vitamin K analogues that could improve seizure control in patients with drug-resistant epilepsy.

29 Oct 2018

Ischemia-induced stem cells can be promising candidates for CNS injury therapeutics

Researchers have performed a careful comparison between locally generated, ischemia-induced, multipotent stem cells and bone marrow-derived mesenchymal stem cells in an effort to determine which cell type has greater central nervous system repair capacity.

26 Oct 2018

Researchers use MRI to watch how electrical stimulation could cure gastrointestinal disorders

More than 60 million people in the U.S. suffer from disorders in the gastrointestinal tract that could be cured by electrical stimulation, but scientists don't fully understand the therapy's effects on a critical organ: the stomach.

25 Oct 2018

'Cancer Gene Census' could help find drug targets and design treatments

Researchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involved in human cancer, the "Cancer Gene Census". Describing all genes strongly implicated in causing cancer, the Census also describes how they function across all forms of this disease.

25 Oct 2018

Scientists engineer antiviral peptide that exploits Achilles' heel of Zika virus

Scientists at Nanyang Technological University, Singapore have engineered an antiviral peptide that exploits the Zika virus at its Achilles' heel - the viral membrane - hence stopping the virus from causing severe infections.

24 Oct 2018

Scientists identify new target for battling deadly form of leukemia

UT Southwestern scientists, working with colleagues at a sister institution in Houston, have identified a new target for battling a deadly form of leukemia.

24 Oct 2018

Study examines factors associated with fasting hyperglucagonemia in type 2 diabetes

A new study examined the relationship between fasting hyperglucagonemia -- which can negatively affect glucose metabolism in patients with type 2 diabetes -- and several biochemical and glycemic factors in subjects with T2D or in a nondiabetic control group.

24 Oct 2018

Scientists develop new class of compounds for treatment of progressive neurodegenerative disorder

St. Jude Children's Research Hospital investigators have developed a new class of compounds that extended the lives and eased symptoms of mice with a progressive neurodegenerative human disorder.

23 Oct 2018

Therapeutics News and Research

C-Path, CHDI and CDISC announce availability of Huntington's Disease Therapeutic Area User Guide

Researchers for first time view serotonin activating its receptor using high-powered microscopes

Integral Molecular wins NIH grant to initiate target discovery program for Alzheimer’s disease

Phase 2 study of ziresovir for treating hospitalized RSV infected infants achieves significant progress

Researchers develop new strategy in the search for psychoactive drugs

IU Philanthropic Venture Fund commits to invest $500,000 to NERx Biosciences company

UC Scientist receives NIH grant for developing new malaria therapeutic strategies

Celprogen successfully prints 3D Brains from brain stem cells to study neurological disease stages

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

Study: Single protein regulates network of genes essential for sperm development

New City of Hope CAR T cell trial focuses on HER2-positive breast cancer patients with brain metastases

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Neuroene Therapeutics receives $1.5 million NIH grant to develop anti-seizure compound for epilepsy

Ischemia-induced stem cells can be promising candidates for CNS injury therapeutics

Researchers use MRI to watch how electrical stimulation could cure gastrointestinal disorders

'Cancer Gene Census' could help find drug targets and design treatments

Scientists engineer antiviral peptide that exploits Achilles' heel of Zika virus

Scientists identify new target for battling deadly form of leukemia

Study examines factors associated with fasting hyperglucagonemia in type 2 diabetes

Scientists develop new class of compounds for treatment of progressive neurodegenerative disorder

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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