Tumor News and Research

RSS

Gene responsible for cholesterol dysregulation in brain cancer cells could be a target for future drugs

Most people relate cholesterol to heart health, but it is also a critical component in the growth and spread of brain cancer.

23 Mar 2021

Stem cell therapy could help restore debilitating age-related muscle loss

As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age.

23 Mar 2021

Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries

Researchers from the Department of Orthopedics of Tongji Hospital at Tongji University in Shanghai have successfully used a nanobiomaterial called layered double hydroxide (LDH) to inhibit the inflammatory environment surrounding spinal cord injuries in mice, accelerating regeneration of neurons and reconstruction of the neural circuit in the spine.

23 Mar 2021

New treatment for late-stage neuroendocrine tumors found to be more effective and less toxic

A new treatment for late-stage neuroendocrine tumors (NETs) has been found to be more effective and have fewer side effects than the current standard of care, according to research published in the March issue of The Journal of Nuclear Medicine.

22 Mar 2021

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Targeted treatment of basal-like breast cancer could be facilitated by YAP inhibitors in the future. As reported by an MDC team headed by Walter Birchmeier in the scientific journal Cancer Research, this type of cancer requires the support of the YAP protein to stimulate the growth of cancer stem cells.

22 Mar 2021

Study reveals the incidence of structural abnormalities in the developing brain

A large study of brain MRI scans from 11,679 nine- and ten-year-old children reviewed by UC San Francisco neuroradiologists identified potentially life-threatening conditions in 1 in 500 children, and more minor but possibly clinically significant brain abnormalities in 1 out of 25 children.

22 Mar 2021

Bacteria residing within tumor cells can boost cancer immunotherapy

Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells.

22 Mar 2021

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

New preclinical research led by Wensheng Wei from Peking University in China has proposed the development of a circular RNA vaccine. Their findings showed the circular RNA vaccine creates neutralizing antibodies and strong T-cell responses against the receptor-binding domain of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

21 Mar 2021

$11 million COBRE funding will help create Center for Pre-Clinical Cancer Research at LSU SVM

The Louisiana State University School of Veterinary Medicine, or LSU SVM, has received an $11 million grant to establish a Center of Biomedical Research Excellence, or COBRE.

19 Mar 2021

VHIO-born spin-off receives approval to initiate Phase I/II clinical trial of novel Myc inhibitor

Co-founded back in 2014 by VHIO's Laura Soucek, CEO of the enterprise, and Marie-Eve Beaulieu, Chief Scientific Officer (CSO) of the company, VHIO-born spin-off Peptomyc S.L. has just announced that it has received approval from the Spanish Agency of Medicines and Medical Devices for conducting clinical trials in Spain (AEMPS), to initiate the first-in-human Phase I/II clinical trial with its first compound - a disruptive Myc inhibitor, Omomyc (OMO-103).

19 Mar 2021

Underrepresentation in genomic databases may affect therapy selection for minority patients

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

19 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Atypical teratoid rhabdoid tumor (ATRT) is a rare brain tumor that predominantly occurs in young children. Scientists at St. Jude Children's Research Hospital used data from two clinical trials to study the molecular groups of ATRT and correlate them with clinical outcomes.

19 Mar 2021

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

Alliance for Cancer Gene Therapy wants to change the C-word from Cancer to Cure -- building on the life changing success of CAR-T therapies for blood cancers, the organization is now focused on the urgent need to translate this success into therapies to fight more types of cancer, such as solid tumor cancers.

19 Mar 2021

Pancreatic cancer cells use adaptive mechanisms to avoid death by starvation

In new findings published online March 18, 2021 in the journal Cancer Cell, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Moores Cancer Center, describe how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread.

19 Mar 2021

Study reveals biomarkers for the prognosis of gastric adenocarcinoma

Low plasma levels of protein TGFB1 and polymorphisms in gene TGFB1 act as biomarkers for the prognosis of gastric adenocarcinoma, according to a study led by the University Complutense of Madrid.

18 Mar 2021

Study explores how CAR T immunotherapy could be used to treat solid tumors

A study recently published in the journal Science looked into how CAR T immunotherapy could be used to treat solid tumors in addition to leukemias. The programming of CAR T cells opens avenues for applying cell therapies to, for example, breast cancer or ovarian cancer in the future.

18 Mar 2021

Tumor News and Research

Gene responsible for cholesterol dysregulation in brain cancer cells could be a target for future drugs

Stem cell therapy could help restore debilitating age-related muscle loss

Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries

New treatment for late-stage neuroendocrine tumors found to be more effective and less toxic

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Study reveals the incidence of structural abnormalities in the developing brain

Bacteria residing within tumor cells can boost cancer immunotherapy

Circular RNA vaccine shows neutralizing activity against B.1.351 variant

$11 million COBRE funding will help create Center for Pre-Clinical Cancer Research at LSU SVM

VHIO-born spin-off receives approval to initiate Phase I/II clinical trial of novel Myc inhibitor

Underrepresentation in genomic databases may affect therapy selection for minority patients

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

Pancreatic cancer cells use adaptive mechanisms to avoid death by starvation

Study reveals biomarkers for the prognosis of gastric adenocarcinoma

Study explores how CAR T immunotherapy could be used to treat solid tumors

Novel cancer-fighting gene therapy enters phase I clinical trial

Could cinnamon modulate the immune response in severe COVID-19?

New way to enhance treatment outcomes for breast cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News