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Study: Mammary basal cell lineage contributes to breast cancer heterogeneity

A key hurdle in treating breast cancers is intratumoral heterogeneity, or the presence of multiple different cell populations within the same tumor that have distinct characteristics such as gene expression, metabolism and ability to divide, spread and grow.

29 Oct 2020

Researchers observe a rapid drop in average body temperature in tropical human population

In the nearly two centuries since German physician Carl Wunderlich established 98.6°F as the standard "normal" body temperature, it has been used by parents and doctors alike as the measure by which fevers -- and often the severity of illness -- have been assessed.

29 Oct 2020

Mouth may be primary route of SARS-CoV-2 infection and transmission

A new study published on the preprint server medRxiv in October 2020 shows that the virus also multiplies robustly in the oral cavity, indicating that saliva plays a role in viral transmission.

29 Oct 2020

COVID-19 mortality rate declines significantly in Sweden

A new observational study by Swedish researchers shows a significant decline in death rates among hospitalized patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their study titled, "Decline in mortality among hospitalized covid-19 patients in Sweden: a nationwide observational study," was released online as a preprint on the medRxiv* server.

28 Oct 2020

Research program aims to thwart prion-like spread of tau pathology in Alzheimer’s disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease. In order for this tau pathology to spread, the protein must interact with heparan sulfate, a sugar molecule found on the surface of neurons.

28 Oct 2020

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Mice fed diets high in sugar developed worse colitis, a type of inflammatory bowel disease (IBD), and researchers examining their large intestines found more of the bacteria that can damage the gut's protective mucus layer.

28 Oct 2020

Study finds no association between leisure activities and lower dementia risk

Studies have suggested that taking part in leisure activities such as playing cards or gardening may be associated with a lower risk of developing dementia.

28 Oct 2020

Antiseizure drug use during pregnancy linked with double the risk of having children with autism

Women with epilepsy who take the antiseizure drug valproic acid while pregnant are at more than double the risk of having children with autism spectrum disorder and nearly double the risk of having children with attention deficit hyperactivity disorder (ADHD), according to a study in the October 28, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Oct 2020

Researchers report outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer

Researchers involved in the phase II NRG Oncology RTOG 0526 trial studying low dose rate (LDR) prostate brachytherapy (BT) following local recurrence (LR) after external beam radiotherapy (EBRT) for patients with low-to-intermediate risk prostate cancer reported late Grade 3 gastrointestinal and genitourinary adverse events (AEs) occurring in 14% of trial participants.

28 Oct 2020

CAC scanning can help doctors decide which patients might benefit from aspirin therapy

An X-ray test commonly used to assess hardening of the arteries could help doctors decide whether the benefits of taking aspirin to prevent a first heart attack or stroke outweigh the risks of bleeding from its use, UT Southwestern research suggests.

28 Oct 2020

Studies suggest the need for a new home-time metric to judge hospital readmissions

Two new studies suggest Medicare's system of penalizing hospitals if too many patients are readmitted within 30 days should also look at whether the patients were well enough to remain in their home during that time.

28 Oct 2020

Researchers reduce positional error in brain-controlled robot arms

By measuring brain signals and implementing a clever feedback scheme, researchers from India and the UK have reduced the positional error in brain-controlled robot arms by a factor of 10, paving the way to greatly enhancing the quality of life for people suffering from strokes and neuro-muscular disorders.

28 Oct 2020

Brain-computer interface enables patients with severe paralysis to resume daily tasks

Researchers demonstrated the success of a fully implantable wireless medical device, the Stentrode™ brain-computer interface (BCI), designed to allow patients with severe paralysis to resume daily tasks -- including texting, emailing, shopping and banking online -- without the need for open brain surgery.

28 Oct 2020

Study: COVID-19 vaccine nationalism could cost the global economy up to $1.2 trillion

Nationalistic behavior by governments may exclude some countries from gaining access to COVID-19 vaccines and cost the global economy up to $1.2 trillion a year in GDP, according to a new study from the not-for-profit research organization RAND Europe.

28 Oct 2020

Autonomous robot uses UV light to kill COVID-19

Ultraviolet light is a form of radiation that can be used for sterilization and disinfection. With schools and offices beginning to meet in-person again despite little change in the rate of COVID-19 infections, easy, low-cost sterilization strategies are necessary to curb the spread of the pandemic.

28 Oct 2020

A systematic review and meta-analysis of stroke in COVID-19 patients

Fourteen out of every 1,000 COVID-19 patients admitted to hospital experience a stroke, a rate that is even higher in older patients and those with severe infection and pre-existing vascular conditions, according to a report published this week.

28 Oct 2020

Physical stress caused by interruptions in workplace

ETH researchers have used an experiment in a simulated group office environment to show for the first time that the body produces more stress hormones when people are repeatedly interrupted at work.

28 Oct 2020

Novel cardiac patch improves recovery from heart attack in rats and pigs

According to the American Heart Association, heart disease is the leading cause of death worldwide in recent years.

28 Oct 2020

New portable arm rehabilitation device launched to help patients perform robot-aided therapy at home

A new portable arm rehabilitation robot will help patients to carry out robot-aided therapy at home, allowing them to perform intensive exercises without visiting hospitals or clinics, which can possibly reduce the risk of exposure to infectious diseases such as COVID-19.

28 Oct 2020

Deep learning models help hunt for COVID-19 drugs

Michigan State University Foundation Professor Guowei Wei wasn't preparing machine learning techniques for a global health crisis. Still, when one broke out, he and his team were ready to help.

28 Oct 2020

Research News and Research

Study: Mammary basal cell lineage contributes to breast cancer heterogeneity

Researchers observe a rapid drop in average body temperature in tropical human population

Mouth may be primary route of SARS-CoV-2 infection and transmission

COVID-19 mortality rate declines significantly in Sweden

Research program aims to thwart prion-like spread of tau pathology in Alzheimer’s disease

High-sugar diet can damage the gut’s protective mucus layer, lead to worse colitis

Study finds no association between leisure activities and lower dementia risk

Antiseizure drug use during pregnancy linked with double the risk of having children with autism

Researchers report outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer

CAC scanning can help doctors decide which patients might benefit from aspirin therapy

Studies suggest the need for a new home-time metric to judge hospital readmissions

Researchers reduce positional error in brain-controlled robot arms

Brain-computer interface enables patients with severe paralysis to resume daily tasks

Study: COVID-19 vaccine nationalism could cost the global economy up to $1.2 trillion

Autonomous robot uses UV light to kill COVID-19

A systematic review and meta-analysis of stroke in COVID-19 patients

Physical stress caused by interruptions in workplace

Novel cardiac patch improves recovery from heart attack in rats and pigs

New portable arm rehabilitation device launched to help patients perform robot-aided therapy at home

Deep learning models help hunt for COVID-19 drugs

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