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New blood test offers breakthrough in myeloma diagnosis and monitoring

Researchers at Dana-Farber Cancer Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions.

8 Aug 2025

Understanding the complex relationship between ultraprocessed foods and health

Ultraprocessed foods or UPFs are a growing concern due to their widespread consumption and impact on potential health risks.

8 Aug 2025

New insights into how SETD2 shapes immunity and disease

The emerging role of SETD2 in regulating immune cell function is shedding light on potential therapeutic strategies for a range of immune-related diseases.

7 Aug 2025

Genetic testing can guide safer chemotherapy for gastrointestinal cancer patients

For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening side effects in those who carry certain genetic variants that can impact how their bodies process the drugs used to treat their disease.

7 Aug 2025

Researchers uncover dozens of traits driven by maternal versus paternal genes

Researchers developed a high-accuracy method to infer whether genetic variants come from the mother or father without needing parental genomes, analysing 286,666 UK Biobank participants. They uncovered over 30 parent-of-origin effects on traits from growth and metabolism to diabetes, many showing opposite effects depending on parental source.

7 Aug 2025

Scientists map the genes behind diet and dementia risk

Researchers established a high-quality genetic dataset from the MIND diet trial, enabling new studies of gene–diet interactions in cognitive health. This resource allows deeper investigation into why individuals respond differently to dietary interventions targeting dementia risk.

6 Aug 2025

Targeting lactate metabolism offers new avenues for cancer treatment

Lactic acid (LA) has transitioned from being perceived as a mere glycolytic waste product to a pivotal regulator of tumor-immune crosstalk.

5 Aug 2025

Redefining PTSD through personal insight and scientific rigor

In a revealing Genomic Press Interview published today in Brain Medicine, Professor Philip Hyland describes his extraordinary journey from personal struggles with anxiety to becoming one of the world's foremost authorities on posttraumatic stress disorders.

5 Aug 2025

Programmable Chromosome Engineering systems enable precise DNA manipulations

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems.

4 Aug 2025

Advancing healthcare with machine learning and big data at Cedars-Sinai

Two new studies from the Department of Computational Biomedicine at Cedars-Sinai are advancing what we know about using machine learning and big data to improve healthcare and medical research.

4 Aug 2025

AI spots hidden diabetes risk even when test results look normal

Researchers used continuous glucose monitoring and multimodal data from over 3,000 people to reveal hidden patterns in glucose spikes across normoglycemia, prediabetes, and type 2 diabetes. Their AI-driven model exposed high individual variability and offers a personalized path for early detection and prevention of diabetes.

3 Aug 2025

Key protein found to guide melanoma cells during spread

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body.

1 Aug 2025

Researchers trace metabolic superpowers of hibernators to shared DNA

Animals that hibernate are incredibly resilient. They can spend months without food or water, muscles refusing to atrophy, body temperature dropping to near freezing as their metabolism and brain activity slow to a crawl.

1 Aug 2025

T cell senescence shapes cancer prognosis and immunotherapy response

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by tumor-associated antigens, metabolic pathway alterations, activation of chronic inflammatory responses, proliferation of immunosuppressive cells, and T cell damage caused by tumor radiotherapy and chemotherapy.

31 Jul 2025

Cancer cells use energy surge to survive physical squeezing

Cancer cells mount an instant, energy‑rich response to being physically squeezed, according to a study published in the journal Nature Communications.

31 Jul 2025

New genetic mutation linked to highly invasive Streptococcus pyogenes infections

A group of researchers led by The University of Osaka have identified a novel genetic mutation in Streptococcus pyogenes, a common bacterium which causes strep throat, significantly associated with severe invasive infections.

30 Jul 2025

Immunotherapy shows promise in changing leukemia’s cellular environment

Scientists studying a hard-to-treat form of blood cancer called acute myeloid leukemia (AML) have found that a type of treatment - immunotherapy - may help change the environment where cancer cells live, possibly helping the immune system respond more effectively.

29 Jul 2025

Groundbreaking Living Brain Project challenges decades of assumptions in neuroscience

In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Alexander W. Charney describes how treating patients with schizophrenia transformed his scientific pursuits from abstract questions to an urgent mission, ultimately leading to discoveries that challenge fundamental assumptions in neuroscience research.

29 Jul 2025

Changing the narrative on hormone-related mood disorders in women

In a wide-ranging Genomic Press Interview published today in Brain Medicine, Dr. David R. Rubinow recounts the serendipitous path that led him to overturn decades of medical assumptions about hormone-related mood disorders in women.

29 Jul 2025

Mexican neuroscientist's journey from exile to schizophrenia research breakthroughs

In a revealing Genomic Press Interview published today in Brain Medicine, Dr. Camilo de la Fuente-Sandoval shares how personal history and scientific passion converged to create groundbreaking advances in schizophrenia treatment prediction.

29 Jul 2025