Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

New air-liquid interface method enhances hair follicle formation in skin organoids

For decades, creating human skin models with physiological relevance has been a persistent challenge in dermatological research.

22 Jan 2025

Study identifies new molecular target for treating keloids

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress.

22 Jan 2025

Study reveals how gut bacteria influence immune cell training and inflammation

A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the intestinal barrier and reach the bone marrow, where they induce epigenetic changes-modifications that alter gene activity without affecting DNA sequence-in the stem cells that give rise to immune cells.

22 Jan 2025

Space research offers new hope for heart cell therapy

A team of researchers led by Emory's Chunhui Xu recently found that heart muscle cells can grow -and survive in the microgravity environment of space.

21 Jan 2025

Study reveals biotin’s potential to mitigate manganese-induced brain damage

While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause health issues.

21 Jan 2025

New imaging protocol enhances visualization of rare bone marrow cells

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to accurately identify rare LepR+ stromal cells.

21 Jan 2025

Ancient viral DNA plays crucial role in early embryo development

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life.

20 Jan 2025

Stem cell therapy shows promise in restoring brain activity after stroke

Every 40 seconds, someone in the United States has a stroke. For survivors of the most common type of stroke, called an ischemic stroke, only about 5 percent fully recover.

17 Jan 2025

Breakthrough reveals how DNA and RNA epigenetics work together to control genes

Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally.

17 Jan 2025

Cigarette smoke alters immune cell function in the lungs

Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of effective treatments.

17 Jan 2025

DDR2 enhances BMP-dependent bone regeneration and reduces heterotopic ossification

Bone loss resulting from trauma, fractures, or disease presents a major global health challenge, often leading to long-term disability.

17 Jan 2025

Inflammasome proteins found to prevent cancer by regulating stem cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

AI deciphers intracellular signals from extracellular recordings in heart cells

A team of researchers led by the University of California San Diego and Stanford University has developed a noninvasive method to monitor the electrical activity inside heart muscle cells from the outside, avoiding the need to physically penetrate the cells.

16 Jan 2025

CAR-NK cells offer safer, more accessible treatment for lymphoma

A new type of cell-based immunotherapy shows promise for B-cell lymphomas and - due to innovations in manufacturing - could make future cellular immunotherapies less expensive and more accessible to patients.

15 Jan 2025

New drug cocktail enhances CAR-T cells for cancer treatment

Preclinical research findings from the University of North Carolina Lineberger Comprehensive Cancer Center identified a cocktail of three different drugs that can be used to generate more robust immune system CAR-Ts (chimeric antigen receptor-T cells) to fight cancer.

13 Jan 2025