Triglyceride News and Research

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Triglycerides are a type of fat in the bloodstream and fat tissue. Too much of this type of fat can contribute to the hardening and narrowing of your arteries. This puts you at risk of having a heart attack or stroke. Diseases such as diabetes, obesity, kidney failure or alcoholism can cause high triglycerides. Often, high triglycerides occur along with high levels of cholesterol, another type of fat. Triglycerides are measured along with cholesterol as part of a blood test. Normal triglyceride levels are below 150. Levels above 200 are high.

Decanoic acid can modulate glucose control

A Van Andel Research Institute (VARI) study published recently in the Journal of Biological Chemistry reveals that a natural fatty acid can serve as a regulator of blood sugar levels, which may have important applications in designing better and safer drugs for diabetes treatment.

22 Nov 2011

Weight loss in obese children reduces adulthood health risks: Study

A new study from the Murdoch Children's Research Institute and Menzies Research Institute has found that obese children who shed weight in later years can reverse the damage done to their health by being overweight and it is really never too late. Overweight people reportedly have an increased risk of type 2 diabetes, clogged arteries or atherosclerosis, high blood cholesterol and high blood pressure.

17 Nov 2011

Niacin not effective in reducing risk of stroke, heart attack in stable CV patients

In patients whose bad cholesterol is very well-controlled by statins for a long time period, the addition of high-dose, extended release niacin did not reduce the risk of cardiovascular events, including heart attack and stroke.

16 Nov 2011

Evacetrapib drug may increase HDL-C and decrease LDL-C levels

Among patients with sub-optimal low-density lipoprotein cholesterol (LDL-C) or high-density lipoprotein cholesterol (HDL-C) levels, use of the drug evacetrapib alone or in combination with statin medications was associated with significant increases in HDL-C levels and decreases in LDL-C levels, according to a study appearing in the November 16 issue of JAMA, a theme issue on cardiovascular disease.

16 Nov 2011

Type 2 diabetics with low cholesterol may carry residual risk of cardiac events

LipoScience, Inc., an in-vitro diagnostic company advancing patient care in cardiovascular, metabolic and other diseases using an innovative and proprietary platform based on nuclear magnetic resonance (NMR) technology, recognizes a presentation of clinical data which suggests that type 2 diabetics with low non-HDL and low LDL cholesterol may carry residual risk of a cardiac event based on high LDL particle numbers.

16 Nov 2011

Sugary drinks raise risk of heart disease in women: Study

A new study shows that women who take sugared beverages every day may be raising their risk for heart disease, even if their habit is not packing on the pounds. The researchers say the drinks could be anything - sweet tea, soda, or coffee drinks that look like desserts.

14 Nov 2011

Salt – is it bad for the heart? Debate continues

Salt or high sodium intake in diet has drawn attention of researchers for a while now. The U.S. Food and Drug Administration held a day-long hearing today, discussing strategies to help Americans cut the salt from their diets as a latest attempt to curb sodium in the American diet.

13 Nov 2011

Dramatic rise in obesity, fatty liver disease increases need for transplants

The dramatic rise in obesity is leading to more fatty liver disease in the United States, increasing the need for more transplants at a time when there already is a severe shortage of donated organs.

11 Nov 2011

TERE1 gene mutation also contributes to invasive bladder cancer

Research conducted by Dr. Jayne S. Weiss, Professor and Chair of Ophthalmology at LSU Health Sciences Center New Orleans, and colleagues has found that a defect in a gene involved in a rare disease of the cornea also contributes to the progression of invasive bladder cancer.

2 Nov 2011

Python heart holds surprises that could be of use in cardiology

The expanding hearts of pythons have intrigued researchers. Leslie Leinwand - a University of Colorado at Boulder molecular biologist who studies heart disease in humans called pythons’ expanding hearts “amazing biology”. “They're not swelling up. They're building (heart) muscle,” he said.

30 Oct 2011

New drug could combat cardiovascular disease

A new therapy being studied in non-human primates by researchers at Wake Forest Baptist Medical Center and colleagues is demonstrating promise as a potential tool for combating cardiovascular disease by increasing good cholesterol and lowering triglycerides in the blood.

29 Oct 2011

Insulin resistance paradox

Obesity and insulin resistance are almost inevitably associated with increases in lipid accumulation in the liver, a serious disease that can deteriorate to hepatitis and liver failure. A real paradox in understanding insulin resistance is figuring out why insulin-resistant livers make more fat. Insulin resistance occurs when the body does a poor job of lowering blood sugars.

27 Oct 2011

Studies find less vitamin D intake among menopausal women

A healthy diet is especially important during the menopause - a period in which the risk of suffering from health problems increases. Various studies analyse the diet of peri- and postmenopausal women in Spain alongside the troubles that come with this transition. The results show that all of those groups studied have a deficient intake of vitamin D.

21 Oct 2011

Inhibition of miR-33a/b suppresses triglyceride levels, increases HDL-C cholesterol

Researchers at NYU Langone Medical Center today announce findings published in the October 20 issue of Nature that show for the first time the inhibition of both microRNA-33a and microRNA-33b (miR-33a/b) with chemically modified anti-miR oligonucleotides markedly suppress triglyceride levels and cause a sustained increase in high density lipoprotein cholesterol (HDL-C) "good" cholesterol.

21 Oct 2011

Phenex commences Px-102 first-in-man Phase I study for Metabolic Syndrome and NAFLD

Phenex Pharmaceuticals AG announced today the start of a first-in-man Phase I study with its clinical drug candidate Px-102, a synthetic non-steroidal FXR agonist. The volunteers of the first dose level received the drug and showed no signs of discomfort or other adverse effects.

19 Sep 2011

USPTO issues notice of allowance to Cenestra Health's omega-3 fatty acid formulations

The U.S. Patent and Trademark Office (USPTO) has issued a notice of allowance related to Cenestra Health's high-purity omega-3 fatty acid formulations and their methods of use.

19 Sep 2011

Aerobic exercise best for belly fat reduction: Study

A new study has shown that the best type of exercise to burn unhealthy belly fat is aerobic exercise. The results showed that people who did aerobics for eight months lost about 2.5 square inches of belly fat, as measured on a CT scan. That's about 1.5 times as much as people who did a combination of aerobic exercise and weight lifting, and about 20 times as much as those who only lifted weights.

31 Aug 2011

Study shows feasibility of combined postprandial glucose and triglyceride tolerance testing

The Homburg Cream and Sugar (HCS) study was designed to determine whether the measurement of postprandial triglyceride in addition to the assessment of glucose tolerance and traditional risk factors might improve the prediction of cardiovascular events.

29 Aug 2011

Low-glycemic foods, high protein intake reduce body weight and fat mass

A new study out of Madrid, Spain shows that low-glycemic foods, and moderately high-protein intake has been shown to reduce body weight and fat mass.

29 Aug 2011

Leucine may help people burn fat during periods of food restriction

Research on Mt. Everest climbers is adding to the evidence that an amino acid called leucine - found in foods, dietary supplements, energy bars and other products - may help people burn fat during periods of food restriction, such as climbing at high altitude, while keeping their muscle tissue.

29 Aug 2011