Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Myriad's EndoPredict offers better prediction of breast cancer recurrence, analysis shows

Myriad Genetics, Inc. today announced that a comparative analysis of commercially available prognostic breast cancer tests in patients with early-stage breast cancer has been published in JAMA Oncology.

19 Feb 2018

FDA approves first treatment to reduce risk of NSCLC progression

The U.S. Food and Drug Administration today approved Imfinzi (durvalumab) for the treatment of patients with stage III non-small cell lung cancer (NSCLC) whose tumors are not able to be surgically removed (unresectable) and whose cancer has not progressed after treatment with chemotherapy and radiation (chemoradiation).

18 Feb 2018

New guidelines offer recommendations for assessment, management of immunotherapy side effects

Immunotherapy with immune checkpoint inhibitors is the first of a new generation of immunotherapy treatments, revolutionizing treatment for many different types of cancer. By unleashing the body's immune system to attack cancer, these treatments can send even the most hard-to-treat cancers into lasting remission.

15 Feb 2018

Cervical tumors may be vulnerable to therapies that attack cancer's fuel supply, study shows

Cancer therapies have improved -- in some cases dramatically -- over the past two decades, but treatment for cervical cancer has remained largely unchanged. All patients receive radiation and chemotherapy, yet despite the aggressive approach, the regimen fails in about one-third of patients with cervical cancer that has spread beyond the cervix but not outside the pelvis.

15 Feb 2018

FDA approves new treatment for non-metastatic, castration-resistant prostate cancer

The U.S. Food and Drug Administration today approved Erleada (apalutamide) for the treatment of patients with prostate cancer that has not spread (non-metastatic), but that continues to grow despite treatment with hormone therapy (castration-resistant). This is the first FDA-approved treatment for non-metastatic, castration-resistant prostate cancer.

15 Feb 2018

Using Smartphones for Cancer Diagnosis and Management

Dr. Castro is a translational oncologist with experience developing and harnessing nanotechnology and molecular imaging platforms for cancer purposes. His work offers a “less is more” approach — to generate robust cancer analyses using scant amount of specimens. Dr. Castro’s research has included funding from the V Foundation for Cancer Research, National Institutes of Health, Ovarian Cancer Research Fund, and the Department of Defense.

From Pittcon 14 Feb 2018

Report identifies potentially modifiable factors that may contribute to persistent risk of SUID

An analysis of trends in sudden unexpected infant death (SUID) over the past two decades finds that the drop in such deaths that took place following release of the 1992 American Academy of Pediatrics (AAP) "back to sleep" recommendations, did not occur in infants in the first month of life.

14 Feb 2018

Trial shows safety, feasibility of adding immunotherapy during chemoradiation for head and neck cancer

Analysis of a clinical trial, RTOG Foundation 3504, finds that nivolumab immunotherapy can be administered safely in conjunction with radiation therapy and chemotherapy for patients with newly diagnosed local-regionally advanced head and neck cancers.

13 Feb 2018

New Blink Reflexometer could provide more objective measures of concussion severity

The Centers for Disease Control and Prevention estimate that between 1.6 and 3.8 million concussions occur each year in the US. In addition, research indicates that nearly a quarter of annual traumatic brain injuries among children are sustained during high-contact/collision recreational activities or sports.

13 Feb 2018

Study reports longer survival for obese men with metastatic melanoma

Obese patients with metastatic melanoma who are treated with targeted or immune therapies live significantly longer than those with a normal body mass index, investigators report in a study published in Lancet Oncology of 1,918 patients in six independent clinical cohorts.

13 Feb 2018

Family history of breast cancer increases risk even in aging women, research finds

Family history of breast cancer continues to significantly increase chances of developing invasive breast tumors in aging women - those ages 65 and older, according to research published in JAMA Internal Medicine.

12 Feb 2018

Researchers use molecular simulations to understand lung cancer drug resistance

Scientists from the Universities of Bristol and Parma, Italy, have used molecular simulations to understand resistance to osimertinib - an anticancer drug used to treat types of lung cancer.

12 Feb 2018

Professor Jean-Charles Soria granted award for pioneering role in cancer drug development

The TAT 2018 Honorary Award for cancer drug development has been granted to Professor Jean-Charles Soria, for his pioneering role in cancer drug development across molecular targeted agents, precision medicine, and immunotherapy.

12 Feb 2018

Lesser-known CRS-HIPEC treatment for cancers that have spread to abdominal cavity

While cancer treatment advances are being made in the areas of precision medicine and immunotherapy, a unique combination of traditional therapies can also provide some cancer patients a treatment option that may provide significant benefit.

11 Feb 2018

Researchers identify link between physical inactivity and lung, head/neck cancers

An increasing body of evidence suggests that a lack of exercise can cause a wide variety of diseases, but physical inactivity is not currently recognized as a risk factor for cancer.

9 Feb 2018

Study of men with inherited DNA repair mutations opens new therapeutic avenues in prostate cancer

Selected by the American Society of Clinical Oncology to first outing during its Genitourinary Cancers Symposium, Translating Evidence to Multidisciplinary Care, February 8 - 10 (San Francisco, USA), Joaquin Mateo, Principal Investigator of VHIO's recently created Prostate Cancer Translational Research Group, will today reveal findings from a retrospective and international study showing for the first time that patients with inherited DNA repair mutations benefit from standard therapies in a similar way to other metastatic prostate cancer patients.

9 Feb 2018

Black patients found to be underrepresented in prostate cancer clinical trials

Clinical trials can offer patients access to cutting-edge treatments with the potential to extend their survival and shape the standard of care in the future.

8 Feb 2018

HDAC6 inhibition could be promising therapeutic approach for peripheral neuropathies

Inhibiting HDAC6 improves the structural stability of cells and protects against neuronal damage. Leuven research uncovered that targeting this mechanism could be a promising therapeutic approach for peripheral neuropathies, whether due to Charcot-Marie-Tooth disease (CMT) or as a side effect of chemotherapy.

8 Feb 2018

New algorithm provides personalized treatment approach for patients with metastatic spine cancer

Every kind of cancer can spread to the spine, yet two physician-scientists who treat these patients describe a paucity of guidance for effectively providing care and minimizing pain.

8 Feb 2018

Researchers identify presence of ER gene fusion proteins in treatment-resistant breast cancer

At Magee-Womens Research Institute and UPMC Hillman Cancer Center, a large team of clinical and laboratory researchers dedicated to understanding treatment resistance in the most common form of breast cancer have identified a new genetic change in the estrogen receptor that contributes to therapy resistance.

7 Feb 2018

Oncology News and Research

Further Reading

Myriad's EndoPredict offers better prediction of breast cancer recurrence, analysis shows

FDA approves first treatment to reduce risk of NSCLC progression

New guidelines offer recommendations for assessment, management of immunotherapy side effects

Cervical tumors may be vulnerable to therapies that attack cancer's fuel supply, study shows

FDA approves new treatment for non-metastatic, castration-resistant prostate cancer

Using Smartphones for Cancer Diagnosis and Management

Report identifies potentially modifiable factors that may contribute to persistent risk of SUID

Trial shows safety, feasibility of adding immunotherapy during chemoradiation for head and neck cancer

New Blink Reflexometer could provide more objective measures of concussion severity

Study reports longer survival for obese men with metastatic melanoma

Family history of breast cancer increases risk even in aging women, research finds

Researchers use molecular simulations to understand lung cancer drug resistance

Professor Jean-Charles Soria granted award for pioneering role in cancer drug development

Lesser-known CRS-HIPEC treatment for cancers that have spread to abdominal cavity

Researchers identify link between physical inactivity and lung, head/neck cancers

Study of men with inherited DNA repair mutations opens new therapeutic avenues in prostate cancer

Black patients found to be underrepresented in prostate cancer clinical trials

HDAC6 inhibition could be promising therapeutic approach for peripheral neuropathies

New algorithm provides personalized treatment approach for patients with metastatic spine cancer

Researchers identify presence of ER gene fusion proteins in treatment-resistant breast cancer

eBook: Liquid biopsy in cancer research eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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