Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Researchers find key mechanism behind Alzheimer's disease

Alzheimer's disease affects more than 26 million people worldwide. It is predicted to skyrocket as boomers age-nearly 106 million people are projected to have the disease by 2050.

7 Sep 2013

Locus coeruleus plays major role in learning, memory and other cognitive functions

Death of neurons in the dorsal raphe nucleus and locus coeruleus is a pathological characteristic of the disease. Previous studies concerning the pathological characteristic of Alzheimer's disease mainly focus on learning and memory-related hippocampus, and less attention has been paid to the locus coeruleus.

6 Sep 2013

Self-propagating aggregates key to Alzheimer's, other diseases

Two leading neurology researchers have proposed a theory that could unify scientists' thinking about several neurodegenerative diseases and suggest therapeutic strategies to combat them.

6 Sep 2013

Longer looks: Phenomenal growth of the Cleveland Clinic prompts hopes for the city; the bittersweet decision to donate organs

Delos M. "Toby" Cosgrove arrived at the Cleveland Clinic in 1975 as an "incredibly poor" 34-year-old dreaming of a life as a cardiac surgeon. … As the years passed he became well-known for pioneering the replacement of heart valves, eventually assuming the chair of the department of cardiothoracic surgery.

From Medtronic 5 Sep 2013

Elan enrolls first patient dosing in phase 2a study of ELND005 in Down syndrome

Elan Corporation, plc (NYSE: ELN) announced today the first patient dosing in a Phase 2a study of ELND005 in Down syndrome. Study ELND005-DS201 will evaluate the safety and pharmacokinetics of 2 doses of ELND005 and placebo in young adults with Down syndrome without dementia, and will also include select cognitive and behavioural measures.

5 Sep 2013

Stress-related protein genetically linked to acceleration of Alzheimer's disease

A stress-related protein genetically linked to depression, anxiety and other psychiatric disorders contributes to the acceleration of Alzheimer's disease, a new study led by researchers at the University of South Florida has found.

5 Sep 2013

Research: Men who exercise vigorously may reduce risk of epilepsy later in life

New research suggests that men who exercise vigorously as young adults may reduce their risk of developing epilepsy later in life. The study is published in the September 4, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. Epilepsy is a brain disease that causes repeated seizures over time.

5 Sep 2013

High-income and better hygiene countries exhibit much higher rates of Alzheimer's

New research has found a "very significant" relationship between a nation's wealth and hygiene and the Alzheimer's "burden" on its population. High-income, highly industrialised countries with large urban areas and better hygiene exhibit much higher rates of Alzheimer's.

5 Sep 2013

Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia

Resveratrol, a polyphenolic compound, is synthesized in several plants and possesses beneficial biological effects, which include anti-oxidant, anti-inflammatory and anti-carcinogenic properties.

5 Sep 2013

Neurodyn acquires all assets related to new drug candidate Memogain from Galantos Pharma

Neurodyn Inc. announced today that it has acquired from Galantos Pharma GmbH, Mainz, Germany all assets related to their Alzheimer's prescription drug candidate - Memogain. Memogain has completed an extensive preclinical development program and is ready to proceed into Phase 1 clinical trials in late 2013. The terms of the acquisition were not disclosed.

5 Sep 2013

Proteins in blood predict women at risk of pre-eclampsia during first pregnancy

Researchers from The University of Manchester and Central Manchester University Hospitals NHS Trust have identified proteins in the blood that could be used to predict whether a woman in her first pregnancy is at increased risk of developing pre-eclampsia.

From The University of Manchester 4 Sep 2013

Study confirms Mediterranean diet associated with better cognitive function

Over recent years many pieces of research have identified a link between adherence to a Mediterranean diet and a lower risk of age-related disease such as dementia.

4 Sep 2013

Avanir Pharmaceuticals enters into patent settlement agreement with Actavis

Avanir Pharmaceuticals, Inc. today announced that it has entered into a settlement agreement with Actavis South Atlantic LLC and Actavis, Inc. (collectively, "Actavis") to resolve pending patent litigation in response to Actavis' abbreviated new drug application seeking approval to market generic versions of Avanir's NUEDEXTA (dextromethorphan hydrobromide/quinidine sulfate) capsules.

4 Sep 2013

Proteins in blood could predict woman at increased risk of developing pre-eclampsia

3 Sep 2013

Still no evidence for causes of Alzheimer's disease by playing football, despite NFL settlement

Despite the NFL's $765 million settlement with retired players, there still is no credible scientific evidence that playing football causes Alzheimer's disease or other neurological disorders, according to Loyola University Medical Center clinical neuropsychologist Christopher Randolph, PhD, who has published multiple studies on the topic.

31 Aug 2013

Research team examines link between genetics and memory problems in Parkinson's patients

A research team at University of Virginia School of Medicine led by Matthew Barrett, MD, MSc, will use a state grant to examine the link between genetics and memory problems in Parkinson's disease patients. Barrett hopes the research will eventually lead to customized treatments for Parkinson's disease patients.

30 Aug 2013

Future of biomedical innovation depends on new trend for all players to work together for common goal

It's a long, expensive, risky road to turn a scientific breakthrough into a treatment that can help patients. Fewer organizations are trying to tackle the challenges alone, says a new paper from MIT researchers published August 28 in the journal Science Translational Medicine.

29 Aug 2013

Study reveals relationship between migraine and low income status

Studies show that migraine is more common among people with lower incomes. This relationship is examined in a study published in the August 28, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology, looking at whether developing migraines limits people's educational and career achievements, leading to a lower income status, or whether problems related to low income such as stressful life events and poor access to health care increase the likelihood of developing migraines.

29 Aug 2013

Study shows that migraine may have long-term effects on the brain's structure

Migraine may have long-lasting effects on the brain's structure, according to a study published in the August 28, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Aug 2013

Study: Deficiency of protein causes age-related memory loss and Alzheimer's disease

A team of Columbia University Medical Center (CUMC) researchers, led by Nobel laureate Eric R. Kandel, MD, has found that deficiency of a protein called RbAp48 in the hippocampus is a significant contributor to age-related memory loss and that this form of memory loss is reversible.

29 Aug 2013

Alzheimer's Disease News and Research

Further Reading

Researchers find key mechanism behind Alzheimer's disease

Locus coeruleus plays major role in learning, memory and other cognitive functions

Self-propagating aggregates key to Alzheimer's, other diseases

Longer looks: Phenomenal growth of the Cleveland Clinic prompts hopes for the city; the bittersweet decision to donate organs

Elan enrolls first patient dosing in phase 2a study of ELND005 in Down syndrome

Stress-related protein genetically linked to acceleration of Alzheimer's disease

Research: Men who exercise vigorously may reduce risk of epilepsy later in life

High-income and better hygiene countries exhibit much higher rates of Alzheimer's

Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia

Neurodyn acquires all assets related to new drug candidate Memogain from Galantos Pharma

Proteins in blood predict women at risk of pre-eclampsia during first pregnancy

Study confirms Mediterranean diet associated with better cognitive function

Avanir Pharmaceuticals enters into patent settlement agreement with Actavis

Proteins in blood could predict woman at increased risk of developing pre-eclampsia

Still no evidence for causes of Alzheimer's disease by playing football, despite NFL settlement

Research team examines link between genetics and memory problems in Parkinson's patients

Future of biomedical innovation depends on new trend for all players to work together for common goal

Study reveals relationship between migraine and low income status

Study shows that migraine may have long-term effects on the brain's structure

Study: Deficiency of protein causes age-related memory loss and Alzheimer's disease

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