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Researchers analyze overall survival rate of prostate cancer patients treated with melatonin

Oncotarget recently published "Melatonin increases overall survival of prostate cancer patients with poor prognosis after combined hormone radiation treatment" which reported that a retrospective study included 955 patients of various stages of prostate cancer who received combined hormone radiation treatment from 2000 to 2019.

11 Feb 2021

Researchers use cachexia model to assess cancer-derived myocardial impairments

Oncotarget recently published "Evaluation of cancer-derived myocardial impairments using a mouse model" which reported that Myocardial damage in cancer patients is emphasized as a cause of death; however, there are not many murine cachexia models to evaluate cancer-derived heart disorder.

11 Feb 2021

Scientists present new outlook on latest trends in peptide drug discovery and development

Currently there are more than 80 peptide drugs on the global market and about twice as many in clinical development.

10 Feb 2021

Freiburg immunologists decipher anti-cancer drug's mode of operation

Rituximab, an anti-cancer drug targeting the membrane protein CD20, was the first approved therapeutic antibody against B tumor cells. Immunologists at the University of Freiburg have now solved a mystery about how it works.

10 Feb 2021

Could Galectin-3 be a potential biomarker to help identify severe COVID-19 early?

Researchers have measured the galectin-3 levels in the sera of hospitalized patients. They found initial high levels indicate patients will become severely ill, suggesting it could be used as a predictor of severe disease.

10 Feb 2021

Inherited genetic variation may affect the response to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer.

10 Feb 2021

MD Anderson and Mirati Therapeutics collaborate to expand evaluation of potent KRAS inhibitors

The University of Texas MD Anderson Cancer Center and Mirati Therapeutics, Inc. today announced a strategic research and development collaboration to expand the evaluation of Mirati's two investigational small molecules, potent and selective KRAS inhibitors - adagrasib (MRTX849), a G12C inhibitor in clinical development, and MRTX1133, a G12D inhibitor in preclinical development, as monotherapy and in combination with other agents - which target two of the most frequent KRAS mutations in cancer.

10 Feb 2021

Study reveals why Black men with prostate cancer have greater survival benefits from immunotherapy

Black men die more often of prostate cancer yet, paradoxically, have greater survival benefits from immunotherapy treatment.

10 Feb 2021

Cellular survival after radiation exposure depends on the specific protein behavior

Exposure to radiation can wreak indiscriminate havoc on cells, tissues, and organs. Curiously, however, some tissues are more vulnerable to radiation damage than others.

10 Feb 2021

A known tumor suppressor gene plays role in stress protection of adult progenitor cells

Adult progenitor cells are present in the Drosophila fly as early as its larvae stage. These cells are the only ones that are maintained throughout development and they are responsible for giving rise to adult tissues and organs.

9 Feb 2021

MSK researchers report an underlying cause of COVID brain

One of the dozens of unusual symptoms that have emerged in COVID-19 patients is a condition that's informally called "COVID brain" or "brain fog."

9 Feb 2021

New drug shows promise in treating pancreatic and breast cancers

ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology.

9 Feb 2021

Older patients often do not receive optimal therapy for esophageal cancers due to perceived risks

Elderly patients (70 years and over) with locally advanced esophageal (E) and esophagogastric junction (EGJ) cancer (located in the stomach and esophagus) should be considered for optimal therapy that has the potential to cure.

9 Feb 2021

Regular walnut intake may help protect against negative outcomes associated with H. pylori infection

A new animal study, published in the Journal of Clinical Biochemistry and Nutrition, suggests regular walnut consumption may be a promising intervention for reducing negative outcomes associated with Helicobacter pylori (H. pylori) infection, a widespread bacterial infection that affects more than half of the world's population.

9 Feb 2021

Study finds way to detect ovarian cancer in patients using Pap test samples

A study led by researchers at the University of Minnesota Medical School found a way to detect the presence of ovarian cancer in patients using Pap test samples, normally used to detect cervical cancer.

9 Feb 2021

Simple blood test can detect a wide range of diseases

In diagnostic medicine, biopsies, where a sample of tissue is extracted for analysis, is a common tool for the detection of many conditions. But this approach has several drawbacks - it can be painful, doesn't always extract the diseased tissue, and can only be used in a sufficiently advanced disease stage, making it, in some cases, too late for intervention.

9 Feb 2021

New platform could help advance genomic medicine research, drug discovery

A Cleveland Clinic-led team of researchers has developed a personalized genomic medicine platform that will help advance accelerate genomic medicine research and genome-informed drug discovery, according to new study results published recently in Genome Biology.

8 Feb 2021

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers.

8 Feb 2021

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

A new nanoparticle-based drug can boost the body's innate immune system and make it more effective at fighting off tumors, researchers at UT Southwestern have shown.

8 Feb 2021

Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model

A combination of radionuclide therapy and immunotherapy has proven successful in slowing the progression of prostate cancer and increasing survival time, according to new research published in the February issue of The Journal of Nuclear Medicine.

8 Feb 2021

Tumor News and Research

Researchers analyze overall survival rate of prostate cancer patients treated with melatonin

Researchers use cachexia model to assess cancer-derived myocardial impairments

Scientists present new outlook on latest trends in peptide drug discovery and development

Freiburg immunologists decipher anti-cancer drug's mode of operation

Could Galectin-3 be a potential biomarker to help identify severe COVID-19 early?

Inherited genetic variation may affect the response to cancer immunotherapy

MD Anderson and Mirati Therapeutics collaborate to expand evaluation of potent KRAS inhibitors

Study reveals why Black men with prostate cancer have greater survival benefits from immunotherapy

Cellular survival after radiation exposure depends on the specific protein behavior

A known tumor suppressor gene plays role in stress protection of adult progenitor cells

MSK researchers report an underlying cause of COVID brain

New drug shows promise in treating pancreatic and breast cancers

Older patients often do not receive optimal therapy for esophageal cancers due to perceived risks

Regular walnut intake may help protect against negative outcomes associated with H. pylori infection

Study finds way to detect ovarian cancer in patients using Pap test samples

Simple blood test can detect a wide range of diseases

New platform could help advance genomic medicine research, drug discovery

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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