Clinical Trial News and Research

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Sleep problems may affect cognitive function of children with chronic kidney disease

Sleep problems and fatigue may affect the cognitive function of children with chronic kidney disease. The findings come from a study that will be presented at ASN Kidney Week 2019 November 5–November 10 at the Walter E. Washington Convention Center in Washington, DC.

8 Nov 2019

National effort to develop implantable bio-artificial kidney achieves key milestone

The Kidney Project, a national effort to develop an implantable bio-artificial kidney that could eliminate the need for dialysis, will announce a key milestone in a November 7, 2019 presentation at the American Society of Nephrology Kidney Week 2019 conference in Washington, DC.

7 Nov 2019

Study may help explain effects of cannabidiol on seizure frequency in Lennox-Gastaut patients

Results from a study published in the British Journal of Clinical Pharmacology may help explain why cannabidiol--a chemical component of marijuana with no psychoactive properties--reduces the frequency of seizures in patients with a severe form of epilepsy.

7 Nov 2019

Study assesses how geriatric assessment can influence cancer care for vulnerable older people

A Wilmot Cancer Institute-led study in JAMA Oncology shows that when physicians fully appreciate the concerns of older adults with cancer, such as function and forgetfulness, it elevates patient care and satisfaction.

7 Nov 2019

Patients with anorexia nervosa face similar health complications as their counterparts with low BMI

Adolescents and young adults with anorexia nervosa whose weight is in the healthy, overweight or obese ranges face similar cardiovascular and other health complications as their counterparts with low body mass index (BMI), according to a new study led by researchers at UCSF.

6 Nov 2019

Nanotechnologies can lead to big advances in cancer therapy

Nami Therapeutics Corporation, which gets its name from the Mandarin word for "nano," is committed to using nanotechnologies to make big advances in cancer therapy.

6 Nov 2019

Gene-editing technique CRISPR trialed for first time as cancer treatment

The go-ahead has been given for the first trials using CRISPR as an alternative therapy for treating cancer.

6 Nov 2019

New stem cell transplant lowers complications for patients with acute blood cancers

The discovery of the UM171 molecule, by Dr. Guy Sauvageau and Anne Marinier, made headlines in 2014 following an article in Science. Hailed by some as a revolution, even a miracle, in the field of blood stem cell transplantation, the UM171 molecule is delivering on its promise.

5 Nov 2019

UM launches CAR-T clinical trial for patients with myasthenia gravis

Neuromuscular experts with the University of Miami Health System and the Miller School of Medicine will launch a Phase 1/2 clinical trial (NCT04146051) using the CAR-T drug, Descartes-08, to treat patients with generalized myasthenia gravis.

5 Nov 2019

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

With CAR T cell therapy, a patient's own immune cells are genetically modified and inserted back into the body to find and kill cancer. This form of immunotherapy has already revolutionized some cancer treatments, but once the CAR T cells are inside a patient, where do they go? How do doctors know that they have successfully reached their target and that they are continuing to fight disease weeks, months, or even years later?

5 Nov 2019

Wake Forest Baptist receives $6 million to study non-pharmaceutical cancer pain management

For many people who've had cancer, severe pain can persist even after treatment ends.

5 Nov 2019

Clinical trial to evaluate effectiveness of biologic augmentation in ACL reconstruction surgery

Marshall University Joan C. Edwards School of Medicine is initiating a new clinical trial to evaluate the efficacy and safety of using biologic augmentation during anterior cruciate ligament, or ACL, reconstruction surgery.

5 Nov 2019

First-in-the-U.S. clinical trial uses deep brain stimulation to tackle opioid addiction

The West Virginia University Rockefeller Neuroscience Institute and WVU Medicine, today (Nov. 5) announced the launch of a first-in-the-U.S. clinical trial using deep brain stimulation for patients suffering from treatment-resistant opioid use disorder.

5 Nov 2019

HIMC at Mount Sinai to evaluate therapeutic effects of novel cancer immunotherapy

The Human Immune Monitoring Center at the Icahn School of Medicine at Mount Sinai will apply cutting-edge high-throughput technologies to evaluate the therapeutic effects of Libtayo (cemiplimab-rwlc), a PD-1 antibody blockade developed by biotechnology company Regeneron Pharmaceuticals, Inc and Sanofi.

5 Nov 2019

Clinical trial tests impact of actual and virtual nature on cancer patients

Researchers at Houston Methodist Cancer Center are exploring whether exposure to nature, through either a live garden or virtual reality, can alleviate pain and distress in cancer patients undergoing chemotherapy, possibly reducing the need for prescription narcotics.

4 Nov 2019

New innovations in technology aim to improve treatment of PTSD among veterans

New technology aims to improve the treatment of post-traumatic stress disorder by allowing veterans to virtually take their doctor with them during prolonged exposure therapy. The system gives the doctor physical and psychological information about the veterans in real time.

2 Nov 2019

Otago researchers join vaccine research project to tackle Salmonella bloodstream infections in Africa

A team of University of Otago researchers is part of a major new international vaccine research project to help tackle devastating Salmonella bloodstream infections which are killing thousands of people in sub-Saharan Africa each year.

1 Nov 2019

Tightening of Ebola care practice rules following survivor’s death

Guidelines for the safe care of Ebola patients are being looked over after a patient's death due to a second infection from Ebola.

1 Nov 2019

Study: Checkpoint inhibitor prolongs survival in patients with head and neck cancers

The checkpoint inhibitor pembrolizumab (Keytruda) offers patients with advanced head and neck cancers longer survival time, according to a new global study led by Yale Cancer Center (YCC). The data was published today in the journal The Lancet.

1 Nov 2019

Three-drug combination improves lung function, reduces symptoms in CF patients

A phase three clinical trial that UT Southwestern participated in determined that a three-drug combination improved lung function and reduced symptoms in cystic fibrosis patients who have a single copy of the most common genetic mutation for the disease.

31 Oct 2019

Clinical Trial News and Research

Sleep problems may affect cognitive function of children with chronic kidney disease

National effort to develop implantable bio-artificial kidney achieves key milestone

Study may help explain effects of cannabidiol on seizure frequency in Lennox-Gastaut patients

Study assesses how geriatric assessment can influence cancer care for vulnerable older people

Patients with anorexia nervosa face similar health complications as their counterparts with low BMI

Nanotechnologies can lead to big advances in cancer therapy

Gene-editing technique CRISPR trialed for first time as cancer treatment

New stem cell transplant lowers complications for patients with acute blood cancers

UM launches CAR-T clinical trial for patients with myasthenia gravis

Penn researchers tag CAR T cells with imaging markers to monitor cancer therapy

Wake Forest Baptist receives $6 million to study non-pharmaceutical cancer pain management

Clinical trial to evaluate effectiveness of biologic augmentation in ACL reconstruction surgery

First-in-the-U.S. clinical trial uses deep brain stimulation to tackle opioid addiction

HIMC at Mount Sinai to evaluate therapeutic effects of novel cancer immunotherapy

Clinical trial tests impact of actual and virtual nature on cancer patients

New innovations in technology aim to improve treatment of PTSD among veterans

Otago researchers join vaccine research project to tackle Salmonella bloodstream infections in Africa

Tightening of Ebola care practice rules following survivor’s death

Study: Checkpoint inhibitor prolongs survival in patients with head and neck cancers

Three-drug combination improves lung function, reduces symptoms in CF patients

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