Pathology News and Research

RSS

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Children's oral language can be a good predictor of future writing difficulties

Children's future writing difficulties can be identified before they even learn how to begin writing, according to a new study by Professor Phaedra Royle and Postdoctoral fellow Alexandra Marquis of the University of Montreal's School of Speech Language Pathology and Audiology.

6 Oct 2014

ERK and JNK enzymes may offer solutions for treating endometrial, colon cancers

In the quest to solve cancer's mysteries, they come in handy when describing tongue-twisting processes and pathways that somehow allow tumors to form and thrive. Two examples are ERK (extracellular-signal-related kinase) and JNK (c-June N-Terminal Kinase), enzymes that may offer unexpected solutions for treating some endometrial and colon cancers.

3 Oct 2014

Schizophrenia and bipolar disorder share common pathophysiological features

Schizophrenia and bipolar disorder both appear to be associated with dendritic spine loss in the brain, suggesting the two distinct disorders may share common pathophysiological features, write author Glenn T. Konopaske, M.D., and colleagues at McLean Hospital, Belmont, Mass., and Harvard Medical School, Boston.

3 Oct 2014

Dendritic spine density also reduced in bipolar disorder

Patients with bipolar disorder have significant dendritic spine loss in the dorsolateral prefrontal cortex, postmortem findings show.

2 Oct 2014

Metamark expands prostate cancer test services to include PROGENSAPCA3 assay

Metamark announced today the expansion of its prostate cancer test services to now include the PROGENSA® PCA3 assay, a urine-based test that can help confirm negative prostate biopsies, and ERG, a companion test to the company's existing PTEN assay.

1 Oct 2014

Protein that plays key role in neurological diseases regulates neuronal communication by self-association

The protein alpha-synuclein is a well-known player in Parkinson's disease and other related neurological conditions, such as dementia with Lewy bodies. Its normal functions, however, have long remained unknown.

30 Sep 2014

Allakos secures additional $10M investment to expand its development portfolio

Allakos Inc. announced today that it has secured an additional $10 million investment from current investors to fund development of an additional therapeutic antibody.

30 Sep 2014

U-M researchers describe new approach to discovering potential cancer treatments

Researchers at the University of Michigan have described a new approach to discovering potential cancer treatments that requires a fraction of the time needed for more traditional methods.

30 Sep 2014

PD-L1 protein could be a potential immunotherapy target for malignant pleural mesothelioma

Treating patients with high-dose radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according to data from a prospective randomized phase II trial presented at ESMO 2014 Congress in Madrid.

30 Sep 2014

Myriad Genetics' Tumor BRACAnalysis CDx identifies 44% more candidates for PARP therapy

Myriad Genetics, Inc. today announced that its Tumor BRACAnalysis CDx- companion diagnostic test significantly improved the detection of cancer-causing BRCA1/2 mutations by 44 percent in women with ovarian cancer. Data from this new study were presented at the 2014 European Society for Medical Oncology annual meeting in Madrid, Spain.

29 Sep 2014

Scientists discover mechanism that resists cancer drugs in estrogen-positive breast cancer

Scientists have discovered a previously unknown mechanism by which estrogen prepares cells to divide, grow and, in the case of estrogen-positive breast cancers, resist cancer drugs. The researchers say the work reveals new targets for breast cancer therapy and will help doctors predict which patients need the most aggressive treatment.

29 Sep 2014

Crizotinib drug effectively halts growth of ROS1-positive lung tumors

Treatment with the targeted therapy drug crizotinib effectively halts the growth of lung tumors driven by rearrangements of the ROS1 gene. In an article receiving Online First publication in the New England Journal of Medicine to coincide with a presentation at the European Society for Medical Oncology meeting, an international research team reports that crizotinib treatment led to significant tumor shrinkage in 36 of 50 study participants and suppressed tumor growth in another 9.

29 Sep 2014

BRD4 protein appears to play key role in keeping stem cells in immature "pluripotent" state

A protein implicated in several cancers appears to play a pivotal role in keeping stem cells in an immature "pluripotent" state, according to a new study by NYU Langone Medical Center scientists.

26 Sep 2014

New approach to create treatments for osteoporosis, autoimmune diseases

Scientists have developed an approach to creating treatments for osteoporosis and autoimmune diseases that may avoid the risk of infection and cancer posed by some current medications.

26 Sep 2014

NeuroEM begins study to test Transcranial Electromagnetic Treatment in aged primates

NeuroEM Therapeutics, Inc., a Phoenix-based medical device R&D company, announced today that it has begun a study with a premiere research university to test its Transcranial Electromagnetic Treatment (TEMT) in aged primates.

25 Sep 2014

Elsevier honored at BMA Medical Book Awards ceremony

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announced today that 28 of its professional and scholarly products were honored at the British Medical Association's annual BMA Medical Book Awards ceremony at BMA House in London on Sept. 22, 2014.

25 Sep 2014

Northwestern scientists develop first animal model for ALS dementia

The first animal model for ALS dementia, a form of ALS that also damages the brain, has been developed by Northwestern Medicine- scientists. The advance will allow researchers to directly see the brains of living mice, under anesthesia, at the microscopic level. This will allow direct monitoring of test drugs to determine if they work.

25 Sep 2014

XenOPAT aims to advance development of new drugs against cancer, personalized cancer treatments

On September 8th, the company XenOPAT SL, a spin-off of the Institute of Biomedical Research and the Catalan Institute of Oncology was established with the aim of bringing the company the latest scientific developments to the service combating cancer with two main branches: the development of new drugs and advance the implementation of personalized cancer treatments.

24 Sep 2014

UC Riverside collaborating on NSF-funded project to study ancient lineages of fungi

The University of California, Riverside is one of 11 collaborating institutions that have been funded a total of $2.5 million by the National Science Foundation for a project focused on studying zygomycetes - ancient lineages of fungi that include plant symbionts, animal and human pathogens and decomposers of a wide variety of organic compounds.

24 Sep 2014

Understanding ways to treat, cure eosinophilic gastritis

Investigators at Cincinnati Children's Hospital Medical Center have published the first study to extensively characterize eosinophilic gastritis (EG).

24 Sep 2014

Pathology News and Research

Further Reading

Children's oral language can be a good predictor of future writing difficulties

ERK and JNK enzymes may offer solutions for treating endometrial, colon cancers

Schizophrenia and bipolar disorder share common pathophysiological features

Dendritic spine density also reduced in bipolar disorder

Metamark expands prostate cancer test services to include PROGENSAPCA3 assay

Protein that plays key role in neurological diseases regulates neuronal communication by self-association

Allakos secures additional $10M investment to expand its development portfolio

U-M researchers describe new approach to discovering potential cancer treatments

PD-L1 protein could be a potential immunotherapy target for malignant pleural mesothelioma

Myriad Genetics' Tumor BRACAnalysis CDx identifies 44% more candidates for PARP therapy

Scientists discover mechanism that resists cancer drugs in estrogen-positive breast cancer

Crizotinib drug effectively halts growth of ROS1-positive lung tumors

BRD4 protein appears to play key role in keeping stem cells in immature "pluripotent" state

New approach to create treatments for osteoporosis, autoimmune diseases

NeuroEM begins study to test Transcranial Electromagnetic Treatment in aged primates

Elsevier honored at BMA Medical Book Awards ceremony

Northwestern scientists develop first animal model for ALS dementia

XenOPAT aims to advance development of new drugs against cancer, personalized cancer treatments

UC Riverside collaborating on NSF-funded project to study ancient lineages of fungi

Understanding ways to treat, cure eosinophilic gastritis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News