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Researchers identify connections between toxoplasmosis and several brain disorders

More than 2 billion people – nearly one out of every three humans on earth, including about 60 million people in the United States – have a lifelong infection with the brain-dwelling parasite Toxoplasma gondii.

14 Sep 2017

Immunotherapy could help some breast cancer patients based on genetic changes in their tumors

Immunotherapy drugs could help some breast cancer patients based on the genetic changes in their tumors, researchers at the Wellcome Trust Sanger Institute and their collaborators find.

13 Sep 2017

Epigenetic changes triggered by cigarette smoke may be earliest step in lung cancer development

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory-grown, human airway cells that a condensed form of cigarette smoke triggers so-called "epigenetic" changes in the cells consistent with the earliest steps toward lung cancer development.

12 Sep 2017

Old lab technique helps researchers better understand circular DNA

A 50-year-old lab technique is helping researchers better understand circular DNA, a lesser-known and poorly understood cousin of the linear version commonly associated with life's genetic blueprint.

12 Sep 2017

Genome sequence cannot predict radiation resistance, say researchers

For the last two decades, researchers worldwide have been using whole genome sequencing to understand what makes cells radiation-resistant, hoping to solve an old biological mystery: why is it that one of the most radiation-resistant organisms, Deinococcus radiodurans, aka "Conan the bacterium," can survive hundreds of times more DNA damage caused by gamma rays than most other organisms? According to a study published recently in Standards of Genomic Sciences by researchers at the Uniformed Services University (USU), the amount of radiation a Deinococcus cell can survive in fact has little to do with the number and types of its DNA repair proteins.

11 Sep 2017

Researchers develop model to explore hard-to-study mutations in human genome

A team of researchers led by a bioinformatician at the University of California San Diego has developed a method to help determine whether certain hard-to-study mutations in the human genome, called short tandem repeats or microsatellites, are likely to be involved in harmful conditions.

11 Sep 2017

Study provides new insights into biologic networks involved in IBD

Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions today published results of an in-depth, multi-omics approach to characterizing the immune component of inflammatory bowel disease (IBD).

11 Sep 2017

Generation Genome: the UK’s genetics revolution?

The report set out the NHS’ intentions of routinizing whole genome sequencing. It is particularly focused towards rare diseases and cancers, although conditions such as obesity, bacterial and other infections are also included.

11 Sep 2017

Machine learning and whole-genomic sequence data could predict physical traits including the face for identification study reveals

A study conducted by a team of researchers from Human Longevity, Inc. (HLI) found that whole-genome sequencing data and machine learning can be used in the prediction of individual faces and other physical traits.

8 Sep 2017

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Cancer immunotherapy drugs only work for a minority of patients, but a generic drug now used to increase blood flow may be able to improve those odds, a study by Columbia University Medical Center researchers suggests.

7 Sep 2017

Myriad Genetics introduces new precision medicine tool to enhance myRisk Hereditary Cancer test

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, announced today that it has launched riskScore, a new clinically validated precision medicine tool to enhance its myRisk Hereditary Cancer test. riskScore quantifies a woman's risk of developing breast cancer by combining genetic markers throughout the genome with her family and clinical history.

7 Sep 2017

New DNA sequencing technology measures effects of thousands of sequences on gene activity

When a gene is switched on, various stretches of DNA nearby act as 'control dials', influencing the level of activity and the amount of gene product that is made.

7 Sep 2017

Controlling zinc transporter levels could be effective plan to combat pancreatic cancer, other diseases

When trace elements rise to toxic levels, bad things happen. Patients suffering from Alzheimer's and Parkinson's disease harbor significantly higher levels of zinc and iron in their brains than healthy patients.

6 Sep 2017

Molecular map shows novel way to stop dangerous bioweapon

During World War II, the Soviet Red Army was forced to move their biological warfare operations out of the path of advancing Nazi troops. Among the dangerous cargo were vials of Francisella tularensis, the organism that causes tularemia and one of the world's most infectious pathogens.

6 Sep 2017

Molecular analysis confirms zoonotic transmission of malaria in Atlantic Forest area in southern Brazil

Malaria was eliminated from southern and southeastern Brazil over 50 years ago, but a number of cases each year in areas of the Atlantic Forest prompted researchers to investigate the possibility of zoonotic transmission - where human beings become infected, via a mosquito bite, with a malaria parasite that usually infects monkeys.

6 Sep 2017

Genome News and Research

Researchers identify connections between toxoplasmosis and several brain disorders

Immunotherapy could help some breast cancer patients based on genetic changes in their tumors

Epigenetic changes triggered by cigarette smoke may be earliest step in lung cancer development

Old lab technique helps researchers better understand circular DNA

Genome sequence cannot predict radiation resistance, say researchers

Researchers develop model to explore hard-to-study mutations in human genome

Study provides new insights into biologic networks involved in IBD

Generation Genome: the UK’s genetics revolution?

Machine learning and whole-genomic sequence data could predict physical traits including the face for identification study reveals

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Myriad Genetics introduces new precision medicine tool to enhance myRisk Hereditary Cancer test

New DNA sequencing technology measures effects of thousands of sequences on gene activity

Controlling zinc transporter levels could be effective plan to combat pancreatic cancer, other diseases

Molecular map shows novel way to stop dangerous bioweapon

Molecular analysis confirms zoonotic transmission of malaria in Atlantic Forest area in southern Brazil

Largest ever genetic study paves way for potential osteoporosis treatment

Scientists show how receptors for drugs act inside cells

Researchers decode complex finger millet genome in high quality for first time

Researchers identify gene variants linked to both type 2 diabetes and CHD risk

Existing drug may one day protect premenopausal women from infertility after cancer treatments

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