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Alzheimer's risk gene APOE4 impacts bone health in females

Scientists at the Buck Institute for Research on Aging, along with collaborators at UC San Francisco, have discovered that APOE4, the most common genetic risk factor for Alzheimer's disease, causes bone quality deficits specifically in female mice, through a mechanism that is invisible to standard imaging and can emerge as early as midlife.

13 Apr 2026

Prostate cancer patients recover faster with TULSA than robotic surgery

A new randomized clinical trial found that men with localized, intermediate‑risk prostate cancer recovered faster and experienced less short‑term impact on their daily lives when treated with MRI‑guided, transurethral ultrasound ablation (TULSA) compared with robotic prostate surgery.

13 Apr 2026

Eardrum perforations and cholesteatoma linked to higher odds of dementia

A new study published in Otolaryngology–Head and Neck Surgery, the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF), finds that two common and treatable causes of conductive hearing loss-eardrum perforations and cholesteatoma, a type of abnormal skin growth in the middle ear-are associated with higher odds of dementia.

13 Apr 2026

Standard naloxone doses may not reverse newer synthetic opioid overdoses

A new study exposes challenges in reversing opioid overdoses with naloxone when potent synthetic drugs like fentanyl and sufentanil are involved, according to a study in the May 2026 issue of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA).

13 Apr 2026

American Heart Association supports research to improve cardiac outcomes for millions of patients

New research is bringing science one critical step closer to understanding what causes cardiac arrest and potentially preventing it.

13 Apr 2026

Targeting senescent fat cells provides new hope for ovarian cancer

Ovarian cancer is the most lethal malignancy of the female reproductive system. Due to its insidious early symptoms and the absence of specific screening modalities, approximately 70% of patients are diagnosed at an advanced stage.

13 Apr 2026

Study reveals brain mechanisms behind post-stroke urinary incontinence

A new USC-led study using functional magnetic resonance imaging (fMRI) reveals the neural mechanisms that contribute to urinary incontinence, a common condition affecting stroke survivors that has a significant impact on their quality of life.

13 Apr 2026

Genetic variants may reduce effectiveness of popular diabetes drugs

More than a quarter of people with Type 2 diabetes take GLP-1 receptor agonists, but the popular diabetes drugs might not work as well for people who have certain genetic variants, according to a new study by Stanford Medicine scientists and their collaborators.

12 Apr 2026

Letrozole monotherapy falls short in ovarian cancer clinical trial

Late breaking results from the phase III NRG GY019 trial indicate that letrozole monotherapy (L) did not demonstrate non inferiority to paclitaxel/carboplatin followed by letrozole (PC/L) for progression free survival (PFS) in patients with newly diagnosed stage II-IV low grade serous carcinoma of the ovary or peritoneum.

11 Apr 2026

Man steps forward to donate kidney to unknown teen

Tim Fitzpatrick was at home on Long Island when he saw a local news story about a 13-year-old boy in need of a kidney transplant.

11 Apr 2026

Nanomedicine offers targeted solutions for breast cancer treatment

Breast cancer (BCA) is one of the most common cancers worldwide, with high mortality and morbidity in women.

10 Apr 2026

New imaging technique captures ultrafast microscopic processes with unprecedented detail

Researchers have developed a new imaging technique that captures more information about ultrafast processes in the microscopic world than was previously possible.

10 Apr 2026

University of Cincinnati launches clinical trial to test new drug for prosthetic joint infections

The University of Cincinnati has enrolled the first patients in a new clinical trial that will test the effectiveness of an investigational drug for prosthetic joint infections (PJI).

10 Apr 2026

For many patients leaving the ICU, the struggle has only just begun

The accident happened in Pittsburgh on Nov. 16. Joseph Masterson, a lawyer who was just days from retiring at age 63, suffered cardiac arrest while driving, plowed into a guardrail, and lost consciousness.

10 Apr 2026

Wireless ureteral stent sleeve enables early detection of hydronephrosis

Ureteral stents are widely used to relieve obstruction and protect kidney function, but they can also become blocked, triggering hydronephrosis and prolonged elevation of intrarenal pressure that may impair renal function.

9 Apr 2026

Mount Sinai ophthalmologist unveils breakthrough ocular fluid monitoring tool

A Mount Sinai ophthalmologist will unveil a novel surgical technology that allows eye surgeons to measure and respond to critical fluid dynamics inside the eye in real time—an advance that may significantly improve precision and outcomes in glaucoma and other ophthalmic procedures.

9 Apr 2026

Microplastics found in human bile may be associated with gallstones

Findings show microplastics in bile may trigger cellular senescence, suggesting a link to gallstone disease and highlighting the need for further research.

9 Apr 2026

New steerable optical fiber reaches previously inaccessible larynx tumors

Worcester Polytechnic Institute (WPI) researchers have developed a flexible optical fiber that can be threaded through a medical endoscope and steered into the larynx to destroy hard-to-reach tumors on the vocal folds, an advance that could expand outpatient laser treatment options for patients whose only other choice might be surgery under general anesthesia.

8 Apr 2026

New clinical guidelines address blood clot prevention in pediatric patients

The American Society of Hematology (ASH) and the International Society on Thrombosis and Haemostasis (ISTH) released comprehensive clinical practice guidelines on anticoagulant prophylaxis in non-cardiac pediatric patients at risk of venous thromboembolism (VTE).

8 Apr 2026

Noninvasive urine test improves prediction of bladder cancer treatment outcomes

Bladder cancer arises from the lining of the bladder, the organ that stores urine, and is one of the most common cancers in the United States. Most patients are diagnosed at an early stage called non-muscle invasive bladder cancer (NMIBC), in which the tumors are confined to the inner layers of the bladder.

7 Apr 2026