Liver News and Research

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Early life exposure to antibacterials could cause irreversible outcomes

Lawrence Livermore National Laboratory scientists have discovered that exposure to environmental levels of triclocarban (TCC), an antibacterial chemical common in personal care products like soaps and lotions as well as in the medical field, can transfer from mother to offspring and interfere with lipid metabolism.

9 Aug 2017

CHLA researchers succeed in better defining rare pediatric malignant liver disease

Investigators at Children's Hospital Los Angeles have succeeded in better defining a rare pediatric malignant liver disease -- a necessary step in achieving an optimum treatment.

9 Aug 2017

Abdominal pain now due to dental braces swallowed 10 years earlier: Case report

In a rarely seen case, a 30-year-old woman presented to the doctors at the emergency department with a worsening pain at the centre of her abdomen. The pain was colicky over the last couple of days and on investigations the team of doctors found that it was due to something she had swallowed years earlier. The report of this case was published this week in the journal BMJ reports.

9 Aug 2017

Researchers receive $3.8 million NIH grant to study medical marijuana's impact on opioid use for pain

The National Institutes of Health has awarded researchers at Albert Einstein College of Medicine and Montefiore Health System a five-year, $3.8 million grant for the first long-term study to test whether medical marijuana reduces opioid use among adults with chronic pain, including those with HIV.

8 Aug 2017

Shortage of Hepatitis B vaccine - prioritization of vaccinations announced in UK

According to a recent announcement made by Public Health England, there is a global shortage of vaccines used against hepatitis B infection. This announcement is followed up by a “prioritisation guidance” which means that persons who are at greatest risk of getting hepatitis B are to be vaccinated on priority if they have not received the vaccine before.

7 Aug 2017

Sugar reduction can lead to improvement in health of overweight children and adults

Osteopathic physicians suggest shifting the conversation from weight to health for overweight children and adults, asking patients to reduce their sugar intake to see measurable improvements in metabolic function.

7 Aug 2017

Gadolinium-based MRI contrast agents deposit in the brain

The International Society for Magnetic Resonance in Medicine has provided new guidance in the use of contrast agents during MRI scans. Emerging research suggests gadolinium-based contrast agents, injected in a patient's veins to brighten tissues in MRI images, accumulate in the brain.

7 Aug 2017

Bioactive 'tissue papers' show potential for regenerative medicine

Northwestern Medicine scientists and engineers have invented a range of bioactive "tissue papers" made of materials derived from organs that are thin and flexible enough to even fold into an origami bird.

7 Aug 2017

Compound derived from cannabis may alter blood levels of antiepileptic drugs

New research published in Epilepsia, a journal of the International League Against Epilepsy (ILAE), suggests that an investigational neurological treatment derived from cannabis may alter the blood levels of commonly used antiepileptic drugs.

7 Aug 2017

Scientists creating blood test to identify breast cancer patients at risk for brain metastasis

Houston Methodist cancer researchers are now closer to creating a blood test that can identify breast cancer patients who are at increased risk for developing brain metastasis, and also monitor disease progression and response to therapy in real time.

4 Aug 2017

Study sheds new light on how anti-cancer agent inhibits tumor growth

Researchers at Sanford Burnham Prebys Medical Discovery Institute have published a study in Nature Communications shedding new light on how K-80003 (TX803), an anti-cancer agent discovered at the Institute, prevents activation of the PI3K pathway, resulting in inhibition of cancer cell growth.

4 Aug 2017

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Omeros Corporation today announced that OMS721 has received orphan drug designation from the U.S. Food and Drug Administration for the treatment of Immunoglobulin A (IgA) nephropathy.

4 Aug 2017

Experimental drug protects mice from obesity-related liver disease

A drug developed at the University of Rochester Medical Center protected mice from one of the many ills of our cheeseburger and milkshake-laden Western diet -- non-alcoholic fatty liver disease.

3 Aug 2017

FDA approves new treatment for all HCV genotypes 1-6

The U.S. Food and Drug Administration today approved Mavyret (glecaprevir and pibrentasvir) to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis, including patients with moderate to severe kidney disease and those who are on dialysis.

3 Aug 2017

FDA approves new combo drug Mavyret for adults with Hepatitis C infection

Yesterday the U.S. Food and Drug Administration gave its approval to Mavyret (glecaprevir and pibrentasvir) for the treatment of adults with chronic hepatitis C infection. These patients are infected with the Hepatitis C virus (HCV) of genotypes 1-6 and are those that have not developed liver cirrhosis or those who have developed mild cirrhosis. The approval for Mavyret was given to AbbVie Inc.

3 Aug 2017

Vascularized 3D bioprinted liver tissue offers more accurate system for drug toxicity testing

Artificially constructed human tissues and organs have been developed with a number of different purposes in mind, from advanced robotics and novel materials to drug screening.

3 Aug 2017

AbbVie hosts roundtable meeting to agree priority actions needed to eliminate hepatitis C in London

Representatives from the London Assembly and local authorities in the Capital are set to meet with third sector and public health representatives in a roundtable meeting hosted by biopharmaceutical company, AbbVie, on World Hepatitis Day.

3 Aug 2017

Mango intake exerts beneficial effects in progression and severity of IBD

Initial results of a study by researchers in the department of nutrition and food science at Texas A&M University in College Station show mango consumption has a positive impact on people with inflammatory bowel disease.

3 Aug 2017

Negocios Now names Loyola Medicine neurologist among 50 most influential Latinos in Chicago

Loyola Medicine neurologist José Biller, MD, has been named to Negocios Now's list of the 50 Most Influential Latinos in the Chicago Area.

2 Aug 2017

FDA gives its nod to new drug Imbruvica (Ibrutinib) for chronic Graft versus Host Disease

The U.S. Food and Drug Administration (FDA) yesterday in a press release informed about the approval of Imbruvica (ibrutinib) for the treatment of adult patients with chronic graft versus host disease (cGVHD) who have previously failed with one or more treatment. This is the first drug that the FDA has given its approval to in this disease condition.

2 Aug 2017

Liver News and Research

Early life exposure to antibacterials could cause irreversible outcomes

CHLA researchers succeed in better defining rare pediatric malignant liver disease

Abdominal pain now due to dental braces swallowed 10 years earlier: Case report

Researchers receive $3.8 million NIH grant to study medical marijuana's impact on opioid use for pain

Shortage of Hepatitis B vaccine - prioritization of vaccinations announced in UK

Sugar reduction can lead to improvement in health of overweight children and adults

Gadolinium-based MRI contrast agents deposit in the brain

Bioactive 'tissue papers' show potential for regenerative medicine

Compound derived from cannabis may alter blood levels of antiepileptic drugs

Scientists creating blood test to identify breast cancer patients at risk for brain metastasis

Study sheds new light on how anti-cancer agent inhibits tumor growth

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Experimental drug protects mice from obesity-related liver disease

FDA approves new treatment for all HCV genotypes 1-6

FDA approves new combo drug Mavyret for adults with Hepatitis C infection

Vascularized 3D bioprinted liver tissue offers more accurate system for drug toxicity testing

AbbVie hosts roundtable meeting to agree priority actions needed to eliminate hepatitis C in London

Mango intake exerts beneficial effects in progression and severity of IBD

Negocios Now names Loyola Medicine neurologist among 50 most influential Latinos in Chicago

FDA gives its nod to new drug Imbruvica (Ibrutinib) for chronic Graft versus Host Disease

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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