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Novel injectable drug for faster healing of broken bones moves closer to clinical trials

One in three adults aged 60 and over suffering from a hip fracture dies within one year. Now, a Purdue University-affiliated startup is moving closer to the start of clinical trials for a novel injectable drug that is targeted to heal broken bones faster and strengthen weak bones.

11 Feb 2020

Research shows how the brain's immune system could be activated to improve memory

When it comes to memory, immune cells are known as the "bad cops" of the brain. But new research shows they could also be turned into "good cops" to power memory and learning.

11 Feb 2020

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

In order to provide the best medical care for newly diagnosed Parkinson's disease (PD) patients, a method of predicting their cognitive and motor progression, beyond using purely clinical parameters, would have major implications for their management.

11 Feb 2020

Study explores how some mammals postpone development of their embryos

How do some mammals postpone the development of their embryos to await better conditions for having offspring? A recent study at the UW Medicine Institute for Stem Cell and Regenerative Medicine explored this reproductive enigma, which can occur in more than 130 species of mammals as well as in some marsupials.

10 Feb 2020

Metformin could help leaky gut

A team of researchers from University of California, San Diego, have successfully used gut organoids in their lab to show the effects of medications to treat conditions such as “leaky gut”. The study was titled, “The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer,” and was published in the journal Life Science Alliance today.

10 Feb 2020

Clinical trial of two investigational drugs for rare, inherited Alzheimer's yields disappointing results

An international clinical trial evaluating whether two investigational drugs can slow memory loss and cognitive decline in people in the early stages of a rare, inherited form of Alzheimer's disease has yielded disappointing results, an initial analysis of the data has shown.

10 Feb 2020

Researchers simulate leaky gut conditions using 3D models of human intestines

Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut" -- in which microbes and other molecules seep out of the intestines -- may be more common, and more harmful, than previously thought.

10 Feb 2020

Researchers receive federal grant to evaluate potential imaging biomarker for Alzheimer's

Researchers at Wake Forest School of Medicine have received a five-year grant worth approximately $2.53 million from the National Institute on Aging to evaluate whether a novel brain-imaging technique can identify Alzheimer's disease in its early stages.

9 Feb 2020

Health care affordability remains a top issue for many middle-aged adults, study finds

Health insurance costs weigh heavily on the minds of many middle-aged adults, and many are worried for what they'll face in retirement or if federal health policies change, according to a new study just published in JAMA Network Open.

9 Feb 2020

Study highlights urgent need to address funding and workforce in palliative care

New research at Trinity College Dublin, published today (Thursday, February 6th, 2020), shows that the number of people dying in Ireland with palliative care needs will increase 84% to 2046.

6 Feb 2020

Researchers suggest new approach of evaluating vascular function earlier in women

Men and women differ in the way their vascular systems age and the rate at which atherosclerosis ― the hardening of artery walls or buildup of arterial blockage ― progresses over time. These sex- and age-related differences have a direct bearing on a woman's risk factors for cardiovascular disease.

6 Feb 2020

New technology distinguishes between two progressive neurodegenerative diseases

Scientists have found a way to distinguish between two progressive neurodegenerative diseases, Parkinson's disease and multiple system atrophy, using a technology developed by a researcher at The University of Texas Health Science Center at Houston.

6 Feb 2020

Analyzing cancer-specific alterations found in tumor's RNA

Researchers at EMBL-EBI were among the leaders of a large international consortium that carried out a joint analysis of data from over 1000 donors of more than 25 cancer types, studying data on their whole genomes along with tumor transcriptome data, which indicates the genes that are active within a tumor.

6 Feb 2020

UMass Lowell researcher receives $2.48 million grant to develop advances in home care safety

A UMass Lowell researcher has been awarded a $2.48 million grant to develop advances in safety for home care aides and clients that will keep pace with an aging population, advances in technology and other factors that are rapidly changing the field.

5 Feb 2020

Cancer mutations may arise decades before diagnosis

Researchers at EMBL's European Bioinformatics Institute and the Francis Crick Institute have analyzed the whole genomes of over 2600 tumors from 38 different cancer types to determine the chronology of genomic changes during cancer development.

5 Feb 2020

Age-linked cognitive decline could be slowed by immune activation

A new study published in February 2020 in the Journal of Experimental Medicine (JEM), reports that activating a specific type of immune cell found in the brain could delay reduced cognition often found in older people, and even prevent neurologic degeneration of age.

5 Feb 2020

New program increases resilience, wisdom and reduces stress among seniors

The United States Census Bureau estimates that by 2060, nearly one in four Americans will be age 65 and older. As America turns increasingly gray, numerous stressors, such as declining health, loss of loved ones or independence, negatively impact the lives of older adults.

5 Feb 2020

Higher abdominal fat linked with reduced cognitive function in older patients with diabetes

Higher levels of abdominal fat were linked with reduced cognitive function in a Clinical Obesity study of older Asians with type 2 diabetes--even in individuals with normal weight.

5 Feb 2020

Research highlights the benefits of physical activity for older adults

Physically active older adults benefit from reduced risks of early death, breast and prostate cancer, fractures, recurrent falls, functional limitations, cognitive decline, dementia, Alzheimer's disease, and depression.

5 Feb 2020

Population‐level study of older adults identifies risk factors for cognitive decline

In older adults with abdominal obesity (excess belly fat), sustained elevations of blood sugar were linked to a higher likelihood of experiencing cognitive decline. In older adults without abdominal obesity, the hormone adiponectin appeared to be a likely risk factor for cognitive decline.

5 Feb 2020

Aging News and Research

Novel injectable drug for faster healing of broken bones moves closer to clinical trials

Research shows how the brain's immune system could be activated to improve memory

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

Study explores how some mammals postpone development of their embryos

Metformin could help leaky gut

Clinical trial of two investigational drugs for rare, inherited Alzheimer's yields disappointing results

Researchers simulate leaky gut conditions using 3D models of human intestines

Researchers receive federal grant to evaluate potential imaging biomarker for Alzheimer's

Health care affordability remains a top issue for many middle-aged adults, study finds

Study highlights urgent need to address funding and workforce in palliative care

Researchers suggest new approach of evaluating vascular function earlier in women

New technology distinguishes between two progressive neurodegenerative diseases

Analyzing cancer-specific alterations found in tumor's RNA

UMass Lowell researcher receives $2.48 million grant to develop advances in home care safety

Cancer mutations may arise decades before diagnosis

Age-linked cognitive decline could be slowed by immune activation

New program increases resilience, wisdom and reduces stress among seniors

Higher abdominal fat linked with reduced cognitive function in older patients with diabetes

Research highlights the benefits of physical activity for older adults

Population‐level study of older adults identifies risk factors for cognitive decline

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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