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Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs) - specialized molecules that can modulate RNA and alter protein production - directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

14 Mar 2023

Using antagonistic drug combinations for selective killing of resistant cancer cells

A new review paper was published in Oncotarget's Volume 14 on March 11, 2023, entitled, "Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells."

14 Mar 2023

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma - the deadliest type of primary brain cancer - and other solid tumors.

14 Mar 2023

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Scientists at the National Institutes of Health and Massachusetts General Hospital in Boston have uncovered a potential new approach against liver cancer that could lead to the development of a new class of anticancer drugs.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

CN Bio appoints Deepak Singh as Vice President of Sales and Marketing

CN Bio has today announced that is has appointed Deepak Singh as Vice President of Sales and Marketing.

From CN Bio 14 Mar 2023

Hyperinflammation triggers long COVID headaches

Researchers characterize the immunological and metabolic alterations involved in chronic headache onset during post-acute sequelae of COVID-19.

13 Mar 2023

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood cells that produce antibodies within tumors.

13 Mar 2023

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

A new study by Columbia University researchers suggests that cholesterol-lowering drugs called statins have the potential to reduce heart disease in people with obstructive sleep apnea regardless of the use of CPAP machines during the night.

13 Mar 2023

Innate immune molecule could be at the root of ALS

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures.

13 Mar 2023

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism.

13 Mar 2023

Research reveals the mechanism that triggers breast cancer 'time bomb'

Scientists have discovered why breast cancer cells that have spread to the lungs may 'wake up' following years of sleep - forming incurable secondary tumors.

13 Mar 2023

Expert Brad Sutton explains how MRI has changed the scope of medical research in 50 years

March 16, 2023, marks 50 years since Paul Lauterbur published his seminal Nature paper establishing zeugmatography - now familiar to most as magnetic resonance imaging or simply MRI - as a viable way to visualize objects with a magnetic field and radiofrequency signals.

13 Mar 2023

Drugs News and Research

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

Using antagonistic drug combinations for selective killing of resistant cancer cells

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

CN Bio appoints Deepak Singh as Vice President of Sales and Marketing

Hyperinflammation triggers long COVID headaches

Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

Innate immune molecule could be at the root of ALS

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

Research reveals the mechanism that triggers breast cancer 'time bomb'

Expert Brad Sutton explains how MRI has changed the scope of medical research in 50 years

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

Minimally invasive technique for fixing bunions does not make flatfoot worse, study shows

Feds move to rein in prior authorization, a system that harms and frustrates patients

The 2022 NICE guidelines for the diagnosis and management of gout

Study: Black patients with pulmonary fibrosis are younger than Hispanic and white counterparts

Key steps for diagnosis and management of orthostatic tachycardia after COVID-19

Seniors with anxiety frequently don’t get help. Here’s why.

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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