Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Telemedicine house calls for Parkinson’s patients: an interview with Dr Ray Dorsey, Johns Hopkins University

Access to neurological care for Parkinson disease is currently limited by distance, disability, and the distribution of doctors.

18 Apr 2013

UTHealth neuroscientists demonstrate new strategy to overcome memory deficits

Neuroscientists at The University of Texas Health Science Center at Houston have taken a major step in their efforts to help people with memory loss tied to brain disorders such as Alzheimer's disease.

18 Apr 2013

FDA authorizes SK Biopharmaceuticals' IND application for SKL15508 to treat CIAS

The Korea-based international pharmaceutical company, SK Biopharmaceuticals, announced today the U.S. Food and Drug Administration has authorized the Investigational New Drug application for SKL15508 to treat cognitive impairment associated with schizophrenia.

18 Apr 2013

Americans with brain diseases have more difficulty in finding a neurologist, new study reveals

Americans with brain diseases such as Alzheimer's disease, Parkinson's disease or multiple sclerosis who need to see a neurologist may face longer wait times or have more difficulty finding a neurologist, according to a new study published in the April 17, 2013, online issue of Neurology-, the medical journal of the American Academy of Neurology.

18 Apr 2013

Research suggests fainting may be genetic while certain triggers may not be inherited

New research suggests that fainting may be genetic and, in some families, only one gene may be responsible. However, a predisposition to certain triggers, such as emotional distress or the sight of blood, may not be inherited.

16 Apr 2013

High levels of blood cholesterol increase risk of AD and heart disease

Researchers at the Linda Crnic Institute for Down Syndrome and the University of Colorado School of Medicine have found that a single mechanism may underlie the damaging effect of cholesterol on the brain and on blood vessels.

16 Apr 2013

Review finds drugs, vitamin supplements may not help prevent cognitive decline in seniors

A review of published research has found no evidence that drugs, herbal products or vitamin supplements help prevent cognitive decline in healthy older adults.

16 Apr 2013

Junk DNA plays important role in brain development

Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.

16 Apr 2013

NeuroDerm enrolls patients for Phase IIa clinical trial of ND0612

NeuroDerm, Ltd. announced today that enrollment of patients is ongoing in its Phase IIa clinical trial of ND0612, a novel drug formulation for the treatment of Parkinson's disease.

16 Apr 2013

Study: p38α MAPK protein functions as important switch to drive inflammatory responses in brain

Even a mild injury to the brain can have long lasting consequences, including increased risk of cognitive impairment later in life. While it is not yet known how brain injury increases risk for dementia, there are indications that chronic, long-lasting, inflammation in the brain may be important.

16 Apr 2013

Nutrition Science Initiative to study link between diet, obesity and obesity-related diseases

Just six months after its official launch, the Nutrition Science Initiative has received a $40 million commitment from the Laura and John Arnold Foundation to fund three experiments investigating the link between diet, obesity, and obesity-related diseases, including diabetes, heart disease, stroke, Alzheimer's disease, and cancer.

15 Apr 2013

Researchers study gene that contributes to late-onset Alzheimer's disease in African-Americans

Researchers at Mayo Clinic in Florida participated in a nationwide study that found minor differences between genes that contribute to late-onset Alzheimer's disease in African-Americans and in Caucasians.

15 Apr 2013

RUB researchers develop new hypothesis on occurrence of Alzheimer's disease

A new hypothesis has been developed by researchers in Bochum on how Alzheimer's disease could occur. They analysed the interaction of the proteins FE65 and BLM that regulate cell division.

15 Apr 2013

Study sheds light on role of microglia during progression of Alzheimer's disease

The plaque deposits in the brain of Alzheimer's patients are surrounded by the brain's own immune cells, the microglia. This was already recognized by Alois Alzheimer more than one hundred years ago. But until today it still remains unclear what role microglia play in Alzheimer's disease.

12 Apr 2013

Alzheimer's Association lauds Obama Administration for dedicating additional $100M to fight Alzheimer's

The Alzheimer's Association commends the Obama Administration for dedicating an additional $100 million within the President's FY 2014 budget toward the fight against Alzheimer's and the implementation of the National Plan to Address Alzheimer's Disease.

12 Apr 2013

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Omeros Corporation today announced positive data in the most commonly used model for studying the clinical and pathological features of multiple sclerosis (MS), further advancing its development program of GPR17-targeting compounds for the treatment of MS. Compounds previously discovered by Omeros that inhibit GPR17, an orphan G protein-coupled receptor (GPCR) unlocked by Omeros, significantly improved function from experimental autoimmune encephalomyelitis (EAE) in mice.

11 Apr 2013

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Scientists at The Scripps Research Institute have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it.

11 Apr 2013

Many HDLS patients still incorrectly diagnosed

The very serious hereditary disease HDLS was discovered in 1984 in Sweden. Many HDLS patients are still incorrectly diagnosed with Alzheimer's disease, MS or Parkinson's disease, but researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have now developed a more certain diagnosis method - and are seeking to find a treatment for the "unknown" neurological disorder.

11 Apr 2013

Incidence of late-onset Alzheimer disease higher among African Americans

In a meta-analysis of data from nearly 6,000 African Americans, Alzheimer disease was significantly associated with a gene that have been weakly associated with Alzheimer disease in individuals of European ancestry, although additional studies are needed to determine risk estimates specific for African Americans, according to a study in the April 10 issue of JAMA, a Genomics theme issue.

11 Apr 2013

Research: African-Americans with ABCA7 gene variant have double risk of developing AD

African-Americans with a variant of the ABCA7 gene have almost double the risk of developing late-onset Alzheimer's disease compared with African-Americans who lack the variant.

10 Apr 2013

Alzheimer's Disease News and Research

Further Reading

Telemedicine house calls for Parkinson’s patients: an interview with Dr Ray Dorsey, Johns Hopkins University

UTHealth neuroscientists demonstrate new strategy to overcome memory deficits

FDA authorizes SK Biopharmaceuticals' IND application for SKL15508 to treat CIAS

Americans with brain diseases have more difficulty in finding a neurologist, new study reveals

Research suggests fainting may be genetic while certain triggers may not be inherited

High levels of blood cholesterol increase risk of AD and heart disease

Review finds drugs, vitamin supplements may not help prevent cognitive decline in seniors

Junk DNA plays important role in brain development

NeuroDerm enrolls patients for Phase IIa clinical trial of ND0612

Study: p38α MAPK protein functions as important switch to drive inflammatory responses in brain

Nutrition Science Initiative to study link between diet, obesity and obesity-related diseases

Researchers study gene that contributes to late-onset Alzheimer's disease in African-Americans

RUB researchers develop new hypothesis on occurrence of Alzheimer's disease

Study sheds light on role of microglia during progression of Alzheimer's disease

Alzheimer's Association lauds Obama Administration for dedicating additional $100M to fight Alzheimer's

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Many HDLS patients still incorrectly diagnosed

Incidence of late-onset Alzheimer disease higher among African Americans

Research: African-Americans with ABCA7 gene variant have double risk of developing AD

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