Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Johns Hopkins scientists identify role of central nervous system cell in development of ALS

Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis, a fatal degenerative disease.

1 Apr 2013

New research shows surgical menopause increases cognitive decline and dementia

Women who abruptly and prematurely lose estrogen from surgical menopause have a two-fold increase in cognitive decline and dementia.

30 Mar 2013

Data shows efficacy of MANF in neuroprotection 6-hydroxydopamine rat models of Parkinson's disease

Amarantus BioScience, Inc., a biotechnology company discovering and developing treatments and diagnostics for diseases associated with neurodegeneration and apoptosis, today reported positive preclinical data for its lead therapeutic MANF in neuroprotection 6-hydroxydopamine (6-OHDA) rat models of Parkinson's disease.

28 Mar 2013

Navidea commences enrollment in NAV4694 Phase 2b study to detect erebral β-amyloid plaque

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that enrollment has commenced in its Phase 2b, open-label, safety and efficacy positron emission tomography imaging study of [18F]NAV4694 for detection of cerebral β-amyloid plaque in subjects diagnosed with Mild Cognitive Impairment.

28 Mar 2013

Researchers reprogramming skin cells into brain cells to understand Alzheimer's disease

Sam Gandy, MD, PhD, of the Icahn School of Medicine at Mount Sinai is leading an international team of researchers working to reprogram skin cells into brain cells to gain a better understanding of Alzheimer's disease.

28 Mar 2013

Fruit flies raised on organic diets record better health outcomes

A new study looking at the potential health benefits of organic versus non-organic food found that fruit flies fed an organic diet recorded better health outcomes than flies fed a nonorganic diet.

27 Mar 2013

Lundbeck, Otsuka reach agreement to develop and commercialize Lu AE58054

H. Lundbeck A/S and Otsuka Pharmaceutical Co., Ltd. today announced a license and development agreement for Lu AE58054, a selective 5HT6 receptor antagonist currently in development for the treatment of Alzheimer's disease.

26 Mar 2013

Two researchers awarded grants to develop indicators, biomarkers for dementia with Lewy bodies

The Lewy Body Dementia Association and the Alzheimer's Drug Discovery Foundation have awarded $100,000 each to Omar El-Agnaf, PhD, of United Arab Amirates University and Michelle Mielke, PhD, of Mayo Clinic Rochester to provide one year of support for their research projects focused on developing indicators, or biomarkers, for dementia with Lewy bodies.

26 Mar 2013

Study: Virus that causes cold sores may be associated with cognitive problems

The virus that causes cold sores, along with other viral or bacterial infections, may be associated with cognitive problems, according to a new study published in the March 26, 2013, print issue of Neurology, the medical journal of the American Academy of Neurology.

26 Mar 2013

DNA damage is part of regular brain activity, say scientists

Scientists at the Gladstone Institutes have discovered that a certain type of DNA damage long thought to be particularly detrimental to brain cells can actually be part of a regular, non-harmful process.

25 Mar 2013

Salk scientists discover how brain keeps track of similar but distinct memories

Ever find yourself racking your brain on a Monday morning to remember where you put your car keys? When you do find those keys, you can thank the hippocampus, a brain region responsible for storing and retrieving memories of different environments-such as that room where your keys were hiding in an unusual spot.

22 Mar 2013

New hope for treating, preventing malaria

Scientists at Oregon Health & Science University and the Portland VA Medical Center have developed a drug that may represent one of the world's best hopes for treating and preventing malaria - a disease that kills more than one million people each year.

22 Mar 2013

Researchers identify new substance in olive oil that reduces risk of Alzheimer's disease

The mystery of exactly how consumption of extra virgin olive oil helps reduce the risk of Alzheimer's disease (AD) may lie in one component of olive oil that helps shuttle the abnormal AD proteins out of the brain, scientists are reporting in a new study. It appears in the journal ACS Chemical Neuroscience.

21 Mar 2013

Genetically modified tomatoes mimic actions of good cholesterol

UCLA researchers have genetically engineered tomatoes to produce a peptide that mimics the actions of good cholesterol when consumed.

20 Mar 2013

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

A multicenter team of researchers, including scientists at Columbia University Medical Center (CUMC), Brigham and Women's Hospital (BWH), Mount Sinai School of Medicine, and Massachusetts Institute of Technology, has developed biodegradable nanoparticles that are capable of delivering inflammation-resolving drugs to sites of tissue injury.

20 Mar 2013

Depression and lower cognitive status are associated with rapid functional decline in Alzheimer's patients

More symptoms of depression and lower cognitive status are independently associated with a more rapid decline in the ability to handle tasks of everyday living, according to a study by Columbia University Medical Center researchers in this month's Journal of Alzheimer's Disease.

20 Mar 2013

Mayo Clinic neurology experts present research findings at AAN meeting

Mayo Clinic neurology experts will present research findings on Parkinson's disease, Alzheimer's disease, sleep disorders, concussions, multiple sclerosis and more at the American Academy of Neurology annual meeting in San Diego, March 16-23.

20 Mar 2013

New Alzheimer's data highlight the disease's deadly toll

According to figures released by the Alzheimer's Association, deaths from Alzheimer's and other forms of dementia rose 68 percent between 2000 and 2010.

20 Mar 2013

Research findings could lead to development of new drugs for gout treatment

Findings from a Loyola University Chicago Stritch School of Medicine study could lead to the development of new drugs to treat gout.

20 Mar 2013

New study reveals management practices improve health care outcomes in hospitals

Researchers have long surmised that management techniques successful in manufacturing and technology sectors may improve health care quality. However, there has been very little evidence about how these practices are disseminated in hospitals and whether they are associated with better performance.

20 Mar 2013

Alzheimer's Disease News and Research

Further Reading

Johns Hopkins scientists identify role of central nervous system cell in development of ALS

New research shows surgical menopause increases cognitive decline and dementia

Data shows efficacy of MANF in neuroprotection 6-hydroxydopamine rat models of Parkinson's disease

Navidea commences enrollment in NAV4694 Phase 2b study to detect erebral β-amyloid plaque

Researchers reprogramming skin cells into brain cells to understand Alzheimer's disease

Fruit flies raised on organic diets record better health outcomes

Lundbeck, Otsuka reach agreement to develop and commercialize Lu AE58054

Two researchers awarded grants to develop indicators, biomarkers for dementia with Lewy bodies

Study: Virus that causes cold sores may be associated with cognitive problems

DNA damage is part of regular brain activity, say scientists

Salk scientists discover how brain keeps track of similar but distinct memories

New hope for treating, preventing malaria

Researchers identify new substance in olive oil that reduces risk of Alzheimer's disease

Genetically modified tomatoes mimic actions of good cholesterol

New biodegradable nanoparticles deliver inflammation-resolving drugs to sites of tissue injury

Depression and lower cognitive status are associated with rapid functional decline in Alzheimer's patients

Mayo Clinic neurology experts present research findings at AAN meeting

New Alzheimer's data highlight the disease's deadly toll

Research findings could lead to development of new drugs for gout treatment

New study reveals management practices improve health care outcomes in hospitals

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