Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Research findings could lead to new sleep therapies to improve memory disorders

A team of sleep researchers led by UC Riverside psychologist Sara C. Mednick has confirmed the mechanism that enables the brain to consolidate memory and found that a commonly prescribed sleep aid enhances the process.

13 Mar 2013

Sleep problems may be indicator of early Alzheimer's disease

Sleep is disrupted in people who likely have early Alzheimer's disease but do not yet have the memory loss or other cognitive problems characteristic of full-blown disease, researchers at Washington University School of Medicine in St. Louis report March 11 in JAMA Neurology.

12 Mar 2013

Results from Orion Pharma’s ORM-12741 phase IIa study on AD

A new drug may improve memory problems in people with moderate Alzheimer's disease, according to a phase IIa study released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013. The drug is called ORM-12741.

12 Mar 2013

Darapladib can significantly reduce leaks in the blood brain barrier

A research team led by Robert Nagele, PhD, of the New Jersey Institute for Successful Aging (NJISA) at the University of Medicine and Dentistry of New Jersey (UMDNJ)-School of Osteopathic Medicine, has demonstrated that the anti-atherosclerosis drug darapladib can significantly reduce leaks in the blood brain barrier.

12 Mar 2013

Buphenyl may protect memory and prevent progression of Alzheimer's

Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer's disease.

12 Mar 2013

Researchers develop new approach to screening potential treatments for Alzheimer's disease

According to a 2012 World Health Organization report, over 35 million people worldwide currently have dementia, a number that is expected to double by 2030 (66 million) and triple by 2050 (115 million).

11 Mar 2013

Early detection of PML may help improve survival and disability levels

The drug natalizumab is effective for treating multiple sclerosis (MS), but it increases the risk of a rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML).

11 Mar 2013

Adrenocorticotropic hormone may help treat people with multiple sclerosis

A new study suggests that treatment with adrenocorticotropic hormone (ACTH) may be helpful for people whose multiple sclerosis (MS) is not well-controlled through their regular treatment. The study was released today and will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

11 Mar 2013

Drugs that combat ageing may be available within five years

Drugs that combat ageing may be available within five years, following landmark work led by an Australian researcher.

11 Mar 2013

Study shows reduction of brain capillaries in mice immunized with amyloid beta

University of British Columbia researchers have successfully normalized the production of blood vessels in the brain of mice with Alzheimer's disease (AD) by immunizing them with amyloid beta, a protein widely associated with the disease.

8 Mar 2013

CALHM1 channel protein releases ATP to make neural taste connections

Saying that the sense of taste is complicated is an understatement, that it is little understood, even more so. Exactly how cells transmit taste information to the brain for three out of the five primary taste types was pretty much a mystery, until now.

7 Mar 2013

USF, Saneron receive patent for transplantation method using umbilical cord blood cells

Researchers at Saneron CCEL Therapeutics and the University of South Florida have received a patent relating to a method for obtaining and using umbilical cord blood cells from a donor or patient to provide neural cells for transplantation aimed at repairing a variety of neurodegenerative diseases of the brain and spinal cord, such as Parkinson's disease, Huntington's disease, multiple sclerosis, Alzheimer's disease as well as brain and spinal cord injury.

7 Mar 2013

Study: Multiple sclerosis patients with cognitive problems have more brain damage

People with multiple sclerosis who have cognitive problems, or problems with memory, attention, and concentration, have more damage to areas of the brain involved in cognitive processes than people with MS who do not have cognitive problems, according to a study published in the March 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Mar 2013

UCLA scientists discover new genetic risk factor for Alzheimer's disease

Scientists at UCLA have discovered a new genetic risk factor for Alzheimer's disease by screening people's DNA and then using an advanced type of scan to visualize their brains' connections.

7 Mar 2013

‘New Frontiers in Neurodegenerative Disease Research’ symposium to be held from Feb. 4-7

At the Keystone Symposium "New Frontiers in Neurodegenerative Disease Research," held 4-7 February in Santa Fe, New Mexico, researchers explored the processes that lead to a variety of diseases, including Alzheimer's and Lou Gehrig's disease (amyotrophic lateral sclerosis, ALS).

7 Mar 2013

Research illuminates why stimulating environment may protect against Alzheimer's disease

"Use it or lose it." The saying could apply especially to the brain when it comes to protecting against Alzheimer's disease.

7 Mar 2013

mTORC2 plays key role in regulating memory formation

Introductions at a party seemingly go in one ear and out the other. However, if you meet someone two or three times during the party, you are more likely to remember his or her name. Your brain has taken a short-term memory - the introduction - and converted it into a long-term one.

7 Mar 2013

CALHM1 protein controls sense of taste, finds study

In collaboration with other research institutions, a Feinstein Institute for Medical Research investigator discovered a new protein that controls the sense of taste. The findings are published in the March issue of Nature.

7 Mar 2013

DBS helps anorexia patients achieve and maintain improvements in body weight, mood and anxiety

In a world first, a team of researchers at the Krembil Neuroscience Centre and the University Health Network have shown that Deep Brain Stimulation (DBS) in patients with chronic, severe and treatment-resistant Anorexia Nervosa (anorexia) helps some patients achieve and maintain improvements in body weight, mood, and anxiety.

6 Mar 2013

UK’s health performance declining compared with 14 EU countries over past 20 years

Six decades of universal free health care, the introduction of widespread public health initiatives (eg, tobacco control, cancer screening, and immunisation), and substantial increases in health expenditure have failed to improve the UK’s health outcomes or longevity ranking against the average of 14 other original members of the European Union, Australia, Canada, Norway, and the USA (EU15+) over the past 20 years.

6 Mar 2013

Alzheimer's Disease News and Research

Further Reading

Research findings could lead to new sleep therapies to improve memory disorders

Sleep problems may be indicator of early Alzheimer's disease

Results from Orion Pharma’s ORM-12741 phase IIa study on AD

Darapladib can significantly reduce leaks in the blood brain barrier

Buphenyl may protect memory and prevent progression of Alzheimer's

Researchers develop new approach to screening potential treatments for Alzheimer's disease

Early detection of PML may help improve survival and disability levels

Adrenocorticotropic hormone may help treat people with multiple sclerosis

Drugs that combat ageing may be available within five years

Study shows reduction of brain capillaries in mice immunized with amyloid beta

CALHM1 channel protein releases ATP to make neural taste connections

USF, Saneron receive patent for transplantation method using umbilical cord blood cells

Study: Multiple sclerosis patients with cognitive problems have more brain damage

UCLA scientists discover new genetic risk factor for Alzheimer's disease

‘New Frontiers in Neurodegenerative Disease Research’ symposium to be held from Feb. 4-7

Research illuminates why stimulating environment may protect against Alzheimer's disease

mTORC2 plays key role in regulating memory formation

CALHM1 protein controls sense of taste, finds study

DBS helps anorexia patients achieve and maintain improvements in body weight, mood and anxiety

UK’s health performance declining compared with 14 EU countries over past 20 years

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