Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study led by investigators at the Johns Hopkins Kimmel Cancer Center.

31 May 2014

Gene regulation responsible for normal breast tissue may also play role in cancer development

About one in eight women in the United States will contract breast cancer in her lifetime. Now new research from Tel Aviv University-affiliated researchers, in collaboration with Johns Hopkins University, has provided another tool to help women, clinicians, and scientists searching for a cure to the one of the most widespread yet incurable diseases on the planet.

30 May 2014

Perelman School wins $10M renewal to study oldest part of human immune system

The National Institute of Allergy and Infectious Diseases has awarded the Perelman School of Medicine at the University of Pennsylvania a five-year, $10 million renewal of a program project to study the oldest part of the human immune system called the complement system, or simply "complement."

30 May 2014

Researchers create experimental blood test that determines BHI by gauging performance of mitochondria

Researchers at the University of Alabama at Birmingham School of Medicine have created an experimental blood test that, for the first time, determines a "Bioenergetic Health Index," or BHI, by gauging the performance of mitochondria, the cell's energy powerhouses.

30 May 2014

Study reveals how BTK mutation triggers drug resistance in CLL patients

A multi-institutional team of researchers has pinpointed exactly what goes wrong when chronic lymphocytic leukemia (CLL) patients develop resistance to ibrutinib, a highly effective, precisely targeted anti-cancer drug.

29 May 2014

Researchers create initial catalog of human proteome, identify 193 novel proteins

Striving for the protein equivalent of the Human Genome Project, an international team of researchers has created an initial catalog of the human "proteome," or all of the proteins in the human body.

29 May 2014

Professor receives grant to develop noninvasive method for detecting breast cancer in excised tumors

The National Science Foundation has awarded a three-year, $388,913 grant to an electrical engineering professor at the University of Arkansas to further her work on an alternative, noninvasive method of detecting breast cancer in excised tumors in real time.

29 May 2014

Initial biopsy with epigenetic test rules out prostate cancer up to 88%

A multicenter team of researchers report that a commercial test designed to rule out the presence of genetic biomarkers of prostate cancer may be accurate enough to exclude the need for repeat prostate biopsies in many — if not most — men.

29 May 2014

Researchers design commercial test to rule out presence of genetic biomarkers of prostate cancer

29 May 2014

Study: Sufficient copies of SMN1 gene extend survival in animals with spinal muscular atrophy

To make up for insufficient amounts of SMN protein, the cause of the inherited neuromuscular disease spinal muscular atrophy (SMA), researchers have successfully delivered a replacement SMN1 gene directly to the spinal cords of animal models of SMA.

23 May 2014

Research reveals pattern of neurocognitive risks in children with cochlear implants

Children with profound deafness who receive a cochlear implant had as much as five times the risk of having delays in areas of working memory, controlled attention, planning and conceptual learning as children with normal hearing, according to Indiana University research published May 22 in the Journal of the American Medical Association Otolaryngology--Head and Neck Surgery.

23 May 2014

Immucor's PreciseType HEA test receives FDA approval to predict blood compatibility

Immucor, Inc., a global leader in transfusion and transplantation diagnostics, announced that the U.S. Food and Drug Administration has granted approval for the company's PreciseType HEA test.

23 May 2014

TUSM scientists receive $11.5M grant to develop innovative treatments for heart failure

Innovative treatments for heart failure are lacking, leaving the nearly six million Americans who suffer from the condition with little hope for a cure.

23 May 2014

Study: RNAi silencing strategy blocks production of mutant huntingtin protein

A targeted gene silencing strategy blocks production of the dysfunctional huntingtin (Htt) protein, the cause of Huntington's disease, a fatal, inherited neurodegenerative disorder.

22 May 2014

Effects of radiofrequency ablation and complete endoscopic resection are equal in dysplastic Barrett's esophagus

According to a new systematic review article, radiofrequency ablation and complete endoscopic resection are equally effective in the short-term treatment of dysplastic Barrett's esophagus, but adverse event rates are higher with complete endoscopic resection.

22 May 2014

Soil bacteria have strategies for fighting antibiotics

Drug-resistant bacteria annually sicken 2 million Americans and kill at least 23,000. A driving force behind this growing public health threat is the ability of bacteria to share genes that provide antibiotic resistance.

22 May 2014

Cholesterol plays vital role in cell mobility and tissue invasion

University of Barcelona's researchers led by Professor Carles Enrich, from the Department of Cell Biology, Immunology and Neurosciences of the Faculty of Medicine at the University of Barcelona and CELLEX Biomedical Research Centre of IDIBAPS, have found that cholesterol plays a key role in cell mobility and tissue invasion.

21 May 2014

Pathology News and Research

Further Reading

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

Gene regulation responsible for normal breast tissue may also play role in cancer development

Perelman School wins $10M renewal to study oldest part of human immune system

Researchers create experimental blood test that determines BHI by gauging performance of mitochondria

Study reveals how BTK mutation triggers drug resistance in CLL patients

Researchers create initial catalog of human proteome, identify 193 novel proteins

Professor receives grant to develop noninvasive method for detecting breast cancer in excised tumors

Initial biopsy with epigenetic test rules out prostate cancer up to 88%

Researchers design commercial test to rule out presence of genetic biomarkers of prostate cancer

Study: Sufficient copies of SMN1 gene extend survival in animals with spinal muscular atrophy

Research reveals pattern of neurocognitive risks in children with cochlear implants

Immucor's PreciseType HEA test receives FDA approval to predict blood compatibility

TUSM scientists receive $11.5M grant to develop innovative treatments for heart failure

Study: RNAi silencing strategy blocks production of mutant huntingtin protein

Effects of radiofrequency ablation and complete endoscopic resection are equal in dysplastic Barrett's esophagus

Soil bacteria have strategies for fighting antibiotics

Cholesterol plays vital role in cell mobility and tissue invasion

New method for identifying bacteria in patient specimens leads to 92% cost reduction

New drug offers promising possibility for treating adults with periodontitis

Substance from pine bark is a potential source for treating melanoma

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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