Immune System News and Research

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A detailed map of latent virus reservoir in individuals with HIV

The latent reservoir is the last bastion of HIV's resistance to a cure. But it is difficult to destroy because it is invisible: the cells in the reservoir harbor virus that is dormant, so they don't have any viral proteins on their surface that would give them away.

30 Sep 2020

Researchers identify the target structures for T-cell response against SARS-CoV-2

Our immune system can efficiently fend off viral diseases. Two types of immune cells play an important role in this process: The T-cells, which firstly can directly destroy virus-infected cells and secondly enable the formation of efficient, virus-neutralizing antibodies by B-cells.

30 Sep 2020

Maternal immune cells could bring SARS-CoV-2 to the placenta

Researchers from Canada and Brazil collaborated to explore the possibility of perinatal transmission of the virus from pregnant mothers to their babies and the risk of preterm birth.

30 Sep 2020

UM171 molecule saves life of young man suffering from severe aplastic anemia

In a world first, a young man suffering from severe aplastic anemia who could not be helped by standard treatments has been given a life-saving blood transplant with the made-in-Canada UM171 molecule.

30 Sep 2020

Researchers develop research model to understand the impact of coronavirus on lungs

Scientists at Boston University's National Emerging Infectious Diseases Laboratories (NEIDL) and the Center for Regenerative Medicine (CReM) joined forces to develop the most relevant research model possible for understanding how the coronavirus virus impacts the lungs, by engineering living, "breathing" human lung cells from stem cells for the task.

30 Sep 2020

Researchers identify a new method to produce miniaturized antibodies

Researchers at the University of Bath in the UK and biopharma company UCB have found a way to produce miniaturized antibodies, opening the way for a potential new class of treatments for diseases.

30 Sep 2020

Novel nasal treatment could protect people from COVID-19

A novel nasal treatment developed to boost the natural human immune system to fight common colds and flu, has proved remarkably successful in reducing COVID-19 viral replication test results, released today, reveal.

30 Sep 2020

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology.

30 Sep 2020

Genetic defects in patients' immune system may underlie severe COVID-19

Worldwide, otherwise healthy adolescents and young people without underlying conditions are sometimes severely affected by COVID-19, with the viral infection in the worst cases quickly becoming life-threatening. But why is this happening?

29 Sep 2020

Australian scientists develop a nasal spray that could stop SARS-CoV-2 infection

The novel product, called INNA-051, is being developed by Ena Respiratory, and laboratory experiments have shown that it reduced viral replication by as much as 96 percent in the animal study. Spearheaded by Public Health England’s (PHE) Deputy Director, Professor Miles Carroll, the new study described the potential treatment and has been published in the open-source preprint server bioRxiv*.

29 Sep 2020

A study contradicting the phenotypical relationship between plasmablasts and developing neutrophils

A team of scientists from Australia challenges the findings of a recent study by Wilk et al. demonstrating that plasmablasts transdifferentiate into developing neutrophils in severe coronavirus disease 2019 (COVID-19). The Australian study is currently available on the bioRxiv preprint server.

29 Sep 2020

Novel immunotherapy platform can connect mussel adhesive proteins to the antibodies

Antibody-based immunotherapy is one of treatment options for cancer immunotherapy by modulating our immune system with therapeutic antibodies.

29 Sep 2020

Variations in inflammatory gene increase the risk of obesity

A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found.

29 Sep 2020

Naturally occurring enzyme holds potential as low-cost therapeutic to treat COVID-19

Researchers from UCLA and China have found that catalase, a naturally occurring enzyme, holds potential as a low-cost therapeutic drug to treat COVID-19 symptoms and suppress the replication of coronavirus inside the body.

29 Sep 2020

Computer model unravels mystery behind severe inflammation in people with COVID-19

A study from the University of Pittsburgh School of Medicine and Cedars-Sinai addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation?

29 Sep 2020

Induction of acute senescence may be a necessary process in hemorrhagic shock

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases.

29 Sep 2020

Antibody improves progression-free survival in patients with advanced prostate cancer

An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasised, castration-resistant prostate cancer.

29 Sep 2020

Specific anti-bacterial T cells are strongly activated in people with moderate to severe COVID-19

A type of anti-bacterial T cells, so-called MAIT cells, are strongly activated in people with moderate to severe COVID-19 disease, according to a study by researchers at Karolinska Institutet in Sweden that is published in the journal Science Immunology. The findings contribute to increased understanding about how our immune system responds against COVID-19 infection.

29 Sep 2020

SARS-CoV-2 re-infection is real but rare: Case study

Now, American researchers have looked at all reported cases of re-infection and the possible reasons behind them. Their study titled, “Re-infection with SARS-CoV-2 and Failure of Humoral Immunity: a case report,” is published online on the preprint server medRxiv in September 2020.

28 Sep 2020

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

University of Texas at Dallas researchers have designed a wearable device that monitors sweat for biomarkers that could signal flare-ups of inflammatory bowel disease (IBD).

28 Sep 2020

Immune System News and Research

A detailed map of latent virus reservoir in individuals with HIV

Researchers identify the target structures for T-cell response against SARS-CoV-2

Maternal immune cells could bring SARS-CoV-2 to the placenta

UM171 molecule saves life of young man suffering from severe aplastic anemia

Researchers develop research model to understand the impact of coronavirus on lungs

Researchers identify a new method to produce miniaturized antibodies

Novel nasal treatment could protect people from COVID-19

Blocking the self-destruction process of enzymes can mitigate age-related diseases

Genetic defects in patients' immune system may underlie severe COVID-19

Australian scientists develop a nasal spray that could stop SARS-CoV-2 infection

A study contradicting the phenotypical relationship between plasmablasts and developing neutrophils

Novel immunotherapy platform can connect mussel adhesive proteins to the antibodies

Variations in inflammatory gene increase the risk of obesity

Naturally occurring enzyme holds potential as low-cost therapeutic to treat COVID-19

Computer model unravels mystery behind severe inflammation in people with COVID-19

Induction of acute senescence may be a necessary process in hemorrhagic shock

Antibody improves progression-free survival in patients with advanced prostate cancer

Specific anti-bacterial T cells are strongly activated in people with moderate to severe COVID-19

SARS-CoV-2 re-infection is real but rare: Case study

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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