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Extracellular vesicle RNA reveals clues about obesity and metabolic disease

Our study examines how RNA in extracellular vesicles (EVs) can provide insights into metabolic phenotypes related to obesity. By using functional genomics approaches, we found a high representation of genes and regulatory elements previously associated with obesity and type 2 diabetes represented by the RNA cargo within these EVs.

15 Jul 2025

Long sitting hours raise breast cancer odds for inactive obese women

Prolonged daily sitting is linked to a higher prevalence of breast cancer in obese women, but only among those who are physically inactive. Regular physical activity eliminates this association, highlighting the importance of movement for breast cancer prevention in high-risk groups.

15 Jul 2025

Canadian obesity trends accelerated after the start of COVID-19 pandemic

Did the COVID-19 pandemic affect obesity rates in Canada? A new study in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.241421 found obesity rates based on body mass index (BMI) increased faster in the 4 years after the start of the pandemic than in the previous 11 years, especially in younger adults.

14 Jul 2025

New guideline recommends proper preconception care for women with diabetes

A joint guideline released today from the Endocrine Society and the European Society of Endocrinology (ESE) recommends women with diabetes receive proper preconception care and access to emerging diabetes technology and therapeutics to manage their blood sugar before, during and after pregnancy.

13 Jul 2025

How five months in Tibet changed the heart and lungs of Beijing workers

Long-term exposure to very high altitude significantly reduces cardiopulmonary function in healthy adults from lowland regions, as shown by declines in aerobic capacity and efficiency after five months in Lhasa, China.

13 Jul 2025

Insecticide exposure could impair mental function in older adults

The study investigates the link between pesticide exposure and cognitive impairment in older adults, suggesting a need for improved prevention strategies.

11 Jul 2025

Early-onset diabetes rates soar among young adults in Sweden

Early-onset type 2 diabetes nearly doubled in Sweden between 2006 and 2021, with the sharpest increases among young adults, ethnic minorities, and those with lower education. Projections show early-onset T2D could triple by 2050, posing a major public health challenge.

10 Jul 2025

Weight loss wipes out senescent fat cells but leaves immune scars, study finds

Researchers have mapped human fat tissue at single-cell resolution, uncovering how obesity alters cellular stress, inflammation, and tissue structure. Weight loss reverses much of this damage, especially senescence in fat and vascular cells, but leaves some immune dysfunction behind.

10 Jul 2025

Improving sleep and lifestyle could reduce heart disease risk in menopausal women

During the menopause transition, only 1 in 5 women have optimal scores using the American Heart Association's health-assessment tool, known as Life's Essential 8 (LE8).

9 Jul 2025

More fiber, fewer health risks: evidence for this easy diet fix

This study reveals that adequate dietary fiber intake is crucial for lowering obesity risk and mortality, supporting its role in effective weight management.

9 Jul 2025

Can dietary copper help protect against dementia and memory loss?

Higher dietary copper intake was linked to better cognitive performance in older US adults, with benefits plateauing above a certain threshold. The effect was especially notable in stroke survivors, but further research is needed to confirm causality.

8 Jul 2025

Tirzepatide tops the charts for blood sugar and weight loss in type 2 diabetes

A large network meta-analysis ranked eight GLP-1 receptor agonists for glycemic, weight, and safety outcomes in adults with type 2 diabetes. Tirzepatide demonstrated the greatest efficacy for glucose control and weight loss, while liraglutide offered the lowest hypoglycemia risk.

7 Jul 2025

Excess weight linked to breast cancer risk in postmenopausal women with cardiovascular disease

New research reveals that excess weight is linked to an especially high risk of developing breast cancer in postmenopausal women with cardiovascular disease.

7 Jul 2025

Eating habits directly influence vaginal microbiome, research finds

A cross-sectional study of young Italian women found that higher intake of animal protein and alcohol is associated with vaginal microbiota dysbiosis, while linolenic acid (a plant-based omega-3) and dietary fiber support beneficial Lactobacillus communities.

7 Jul 2025

Vaping versus smoking’s impact on male fertility

A new study found that male E-cigarette users undergoing IVF had higher sperm motility and lower miscarriage rates compared to conventional smokers. However, E-cigarettes were not shown to be safe and further research is needed before recommending them for fertility.

6 Jul 2025

Are you at risk? Waist size, not weight, could affect fertility in women

Researchers found that higher relative fat mass (RFM), a measure of visceral body fat, is significantly associated with increased infertility risk in U.S. women aged 20–44. The study suggests RFM may be a more sensitive screening tool for infertility risk than traditional BMI, especially in women with normal weight but high visceral fat.

3 Jul 2025

Poor lifestyle habits nearly double your chance of developing AFib

A large Framingham Heart Study analysis found that adults with poor cardiovascular health scores on the Life’s Essential 8 were nearly twice as likely to develop atrial fibrillation as those with ideal scores. Maintaining healthy lifestyle habits, especially optimal BMI, blood pressure, and glucose, may help reduce AF risk.

2 Jul 2025

Mediterranean diet wins on weight but misses on memory in diverse aging population

A 14-month randomized trial in older African American adults with obesity found that adopting a Mediterranean diet, with or without calorie-restricted weight loss, significantly improved diet quality and reduced body weight and visceral fat. However, no cognitive benefits were observed compared to usual diet.

2 Jul 2025

Plant-based fitness supplements for reversing metabolic syndrome

Research indicates that specific plant-based supplements, combined with exercise, can improve cardiometabolic markers in those at risk for metabolic syndrome.

2 Jul 2025

New brain scan tool predicts aging speed and dementia risk

Any high school reunion is a sharp reminder that some people age more gracefully than others. Some enter their older years still physically spry and mentally sharp. Others start feeling frail or forgetful much earlier in life than expected.

1 Jul 2025