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Clemson researchers discover a promising therapy for people suffering from toxoplasmosis

Many doctors caution their pregnant patients to avoid cat feces; even the family pet's litter box is off-limits. Now, a group of researchers from Clemson University have discovered a promising therapy for those who suffer from toxoplasmosis, a disease caused by the microscopic protozoa Toxoplasma gondii.

11 May 2022

Review portrays clinical journey of messenger RNA vaccines and mRNA-based therapies

Researchers reviewed messenger ribonucleic acid (mRNA) technology and highlighted its clinical applications.

11 May 2022

Cancer cells in an acidic environment undergo lipid synthesis and accumulation, study shows

Alterations in metabolic processes are a hallmark of cancer and can lead to a tumor environment that is acidic. As a result, cancer cells must adapt to survive in this inhospitable environment.

10 May 2022

A hybrid, multiscale, individual-based model to study the within-host spread of SARS-CoV-2 and the subsequent innate immune response

In this study, the authors have specifically studied the interactions of epithelial cells, a subset of cytokines and macrophages.

10 May 2022

Injectable hydrogels for single-dose COVID-19 vaccination

Several coronavirus disease 2019 (COVID-19) vaccines require multiple doses for long-lasting immunity. However, a new study published in the journal Biomacromolecules has developed a promising single-dose vaccine platform using an injectable hydrogel containing an epitope-labeled plant virus, Cowpea mosaic virus (CPMV).

4 May 2022

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

A new study published in the journal Gastroenterology used upper and lower gastrointestinal endoscopy to assess whether gut antigen persistence leads to post-acute COVID-19 in patients with or without post-acute COVID-19 symptoms.

3 May 2022

Elevated BMI may exacerbate abnormalities associated with aging sperm cells

Single-cell analysis of autopsied human testes suggests that abnormalities associated with aging sperm cells might be exacerbated by elevated body mass index (BMI).

2 May 2022

New insights on the mechanisms of transmission of bacterial pathogen that causes listeriosis

Listeriosis is a zoonotic disease of food origin that can cause, both in the human species and in animals, symptoms of gastroenteritis, meningitis, bacteremia and miscarriages.

2 May 2022

Researchers investigate O-glycosylation in cells infected with Ebola

Researchers from the Copenhagen Center for Glycomics have been investigating O-glycosylation in cells infected with Ebola virus in order to better understand the disease.

28 Apr 2022

Researchers unravel why neuropsychiatric symptoms appear in Alzheimer's patients before memory loss

Researchers from Indiana University School of Medicine are studying why neuropsychiatric symptoms, such as apathy and irritability, appear in most Alzheimer's disease patients before the onset of memory loss.

28 Apr 2022

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

Superior T-cell immunity in COVID vaccinated

A recent study published in the journal Public Library of Science (PLOS) ONE presented the T cell and humoral immune responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and infection against the SARS-CoV-2 original and mutant strains.

27 Apr 2022

New insights into the link between EMFs, calcium and Alzheimer’s disease

For almost a quarter of a century, researchers have been studying and publishing on the effect of calcium on Alzheimer's Disease. Research has led to the development of the calcium hypothesis of Alzheimer's disease, which argues that Alzheimer's is caused by excessive intracellular calcium.

26 Apr 2022

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

First product within new ‘in-a-box’ range, which harnesses next-generation, human-relevant Liver-on-a-Chip technology to improve the accuracy and efficiency of NASH drug discovery.

From CN Bio 26 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Researchers develop a live imaging system to observe collagen synthesis

"Proteins are the building blocks of our body": You have probably heard this phrase before. Proteins are essential to the formation of our body's structures, and their functioning.

21 Apr 2022

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

In a new study, researchers assessed the impact of the SARS-CoV-2 Omicron variant on infected human cells and organs.

20 Apr 2022

Study demonstrates subset of vaccine-induced HLA-A*24:02-restricted T cells exhibits enhanced reactivity against the Omicron BA.1 variant

Researchers characterized vaccine-induced T cell response specific for spike proteins of several SARS-CoV-2 variants.