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Obesity and Alzheimer’s linked through early metabolic disruptions

By 2030, the population in the United States aged 65 and older is expected to reach 71 million or about 20% of Americans. This growth is likely to increase the burden of age-related diseases, particularly Alzheimer's disease (AD), affecting about 1 in 9 adults over 65.

5 May 2026

Study reveals epigenetic adaptation of beta cells across lifespan and disease

As people age, most maintain normal blood sugar even as insulin resistance tends to rise. New research suggests that pancreatic beta cells help meet this demand through gradual epigenetic changes in regulatory regions of the genome that support beta-cell identity and function.

5 May 2026

GADD45B promotes apoptosis in intestinal injury through DNA demethylation

Intestinal ischemia/reperfusion (I/R) injury is a common pathophysiological phenomenon that is widely present in various primary intestinal diseases and systemic critical illnesses, potentially leading to multiple organ dysfunction and failure, with high morbidity and mortality.

5 May 2026

Consumption of eggs can decrease risk of Alzheimer's

Consumption of eggs is associated with a lower risk of being diagnosed with Alzheimer's Disease for those 65 years and older, according to researchers at Loma Linda University Health.

5 May 2026

Study highlights stigma surrounding popular GLP-1 weight loss drugs

Glucagonlike peptide-1 (GLP-1) medications have taken over the national conversation around weight loss.

4 May 2026

Dopamine may stretch time perception and shape lasting memories

Ever heard of getting a "dopamine hit" from something you enjoy? These exciting moments also appear to influence memory, although perhaps not in the way you'd expect.

4 May 2026

Using symptom dimensions may provide more precise, personalized mental health care

A researcher from the University of Kansas has led a large-scale study of university undergraduates to better understand how psychological conditions such as depression, anxiety, post-traumatic stress disorder and eating disorders are connected.

4 May 2026

New research identifies stress response as trigger for heart inflammation

After a heart attack, the body rapidly floods the injured heart with neutrophils - white blood cells that help repair damage but can also make it worse when too many arrive too quickly.

4 May 2026

Study: One in ten babies regularly falls asleep with a screen

Despite recent government guidelines that parents should avoid screen time for babies under the age of two, a new global study finds that one in ten babies now regularly fall asleep with a screen.

4 May 2026

How a common gut bacterium may protect health

Akkermansia muciniphila's impact on immunity and pregnancy outcomes underscores its promise as a probiotic, with implications for infectious disease treatment.

4 May 2026

Finding new ways to mimic ketamine’s antidepressant effects

Weill Cornell Medicine investigators have "reverse engineered" ketamine's antidepressant effects to identify potential new strategies for treating depression.

4 May 2026

High-intensity interval exercise is most effective for heart patients

Endothelial dysfunction is a hallmark of cardiovascular disease (CVD) and plays a central role in vascular inflammation, thrombosis, and impaired vasodilation.

4 May 2026

Study debunks steroid myths, framing creatine as an essential energy-providing molecule

Creatine, a compound often associated with gym-goers and athletes, has long been touted as a performance-enhancing supplement. But beyond the hype, what does science actually reveal about its effects on the body and mind?

4 May 2026

Strong governance needed before widespread use of medical AI

Flinders University experts are warning that artificial intelligence (AI) must be carefully evaluated and governed before it is adopted widely in healthcare, saying rapid advances do not automatically translate into safe use for patients.

30 Apr 2026

Early institutional care linked to shorter life expectancy decades later

Infants who grew up in early child care institutions in the 1950s have a much shorter life expectancy than the general population, a long-term study of individuals in Zurich has shown

30 Apr 2026

Pathogens drive inflammation by reprogramming host cell metabolic processes

An intestinal pathogen reshapes the gut environment to fuel its own colonization and cause diseases, a multi-institutional team including researchers at Vanderbilt Health has discovered.

30 Apr 2026

Inflammation from leaking mitochondria drives aggressive pancreatic cancer growth

Scientists at The Wistar Institute and clinical researchers from ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a vulnerability in pancreatic cancer that could be targeted as a potential therapy.

30 Apr 2026

Silencing a cellular stress signal could extend human lifespan

Silencing a major cellular stress signal could be the key to a longer life, according to new University of Sheffield research.

30 Apr 2026

Study suggests birth weight affects kidney resilience in ultramarathon athletes

A new study is raising questions about whether human endurance has biological limits shaped long before adulthood-possibly beginning at birth.

30 Apr 2026

Metabolic rewiring could help CAR-T cells fight solid tumors

This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells inside solid tumors. It highlights metabolic reprogramming as a promising strategy to improve CAR-T cell persistence, adaptability, and anti-tumor function.

29 Apr 2026