Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New system can help spot sleep disturbance in people with early dementia

A new sleep pattern monitoring system has been developed by UK researchers to help spot sleep disturbance in people diagnosed with early dementia. The system, known as PAViS, could be used remotely by healthcare workers to view sleep profiles and analyse sleep patterns based on sensory data gathered at the patient's home.

19 Feb 2013

Brain damage can persist for decades after original head trauma

As the National Football League braces for lawsuits by 4000 former players alleging the league failed to protect them from the long-term consequences of concussions, game-changing research by a leading Canadian researcher shows damage to the brain can persist for decades after the original head trauma.

17 Feb 2013

Brain health just as important as physical health

We all know the importance of keeping healthy and are familiar with the refrains of 'exercise more', 'eat better' and 'get regular physicals'. But what about our mental health? Professor Barbara Sahakian, best known for her expertise on cognitive enhancers, challenges society (and government) to prioritise mental health in the same way as we do physical health.

17 Feb 2013

The Y rolls out new health program targeting diabetes

YMCAs will advance the program nationally with support from insurers and employers. Also in the news, researchers express concern about the increasing costs likely to accompany soaring Alzheimer's disease rates.

16 Feb 2013

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease.

16 Feb 2013

Tau release from healthy neurons can be regulated by neuronal activity

Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death.

16 Feb 2013

Protein-restricted diet supplemented with IGF-I may protect from Alzheimer's

Mice with many of the pathologies of Alzheimer's Disease showed fewer signs of the disease when given a protein-restricted diet supplemented with specific amino acids every other week for four months.

15 Feb 2013

Targacept reports net loss of $15.9 million for fourth quarter 2012

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today reported its financial results for the fourth quarter and year ended December 31, 2012.

14 Feb 2013

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems.

14 Feb 2013

Antibody therapeutics targeting GPCRs to be developed by alliance between MorphoSys and Heptares

MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) and UK-based Heptares Therapeutics, the leading GPCR drug discovery and development company, have signed an agreement to discover novel antibody therapeutics targeting G protein-coupled receptors (GPCRs), which are membrane proteins involved in a broad range of biological processes and diseases.

13 Feb 2013

Study finds abnormal production of C9RANT in patients with ALS, frontotemporal dementia

Researchers at Mayo Clinic have discovered an abnormal protein that accumulates in the brains of many patients affected with two common neurodegenerative disorders — amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease, and frontotemporal dementia.

13 Feb 2013

Four-month instructional dance program can improve health of Latino seniors

Vigorous activity can improve the physical and mental health of older adults, but for many, particularly Latinos, exercise is not a regular part of their lives, according to a University of Illinois at Chicago researcher.

11 Feb 2013

Experts discuss hottest topics in Alzheimer's brain imaging at 7th HAI conference

At the 7th Human Amyloid Imaging conference held last month in Miami, Florida, 250 experts discussed the hottest topics in Alzheimer's disease brain imaging.

11 Feb 2013

FDA issues draft guidance on developing new treatments for Alzheimer's

Today, the U.S. Food and Drug Administration issued a proposal designed to assist companies developing new treatments for patients in the early stages of Alzheimer's disease, before the onset of noticeable (overt) dementia.

11 Feb 2013

Report: The number of Americans with Alzheimer's disease will almost triple by 2050

The government-funded report projects the Alzheimer's cases will rise from 5 million to about 13.8 million, thereby straining the nation's health care system.

10 Feb 2013

Roundup: Assisted suicide legalization urged; Abortion bill tensions in Wash., Ore.; Budget squeezes in Ga., Conn.

A push for the legalization of physician-assisted suicide is under way in a half-dozen states where proponents say they see strong support for allowing doctors to prescribe mentally competent, dying individuals with the medications needed to end their own lives. ... Groups such as Compassion & Choices, a national end-of-life advocacy organization, have been working to advance the cause.

10 Feb 2013

Drugs that target retromer pathway could help prevent or treat Parkinson's

Columbia University Medical Center (CUMC) researchers have identified a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson's disease.

9 Feb 2013

Alzheimer's appears to be on the rise

The number of people with Alzheimer's disease is expected to triple in the next 40 years, according to a new study by researchers from Rush University Medical Center published in the February 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Feb 2013

Nerve stimulator may be new option for migraine sufferers

Wearing a nerve stimulator for 20 minutes a day may be a new option for migraine sufferers, according to new research published in the February 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Feb 2013

Society of Toxicology's 52nd Annual Meeting to be held from Mar. 10-16 in San Antonio

A group of 7,000 scientists working in multiple specialties, from more than 50 countries, will meet March 10-14, 2013 at the Henry B. Gonzalez Convention Center in San Antonio, Texas, to share their latest findings on 60 topical issues of concern to human health and the environment.

7 Feb 2013

Alzheimer's Disease News and Research

Further Reading

New system can help spot sleep disturbance in people with early dementia

Brain damage can persist for decades after original head trauma

Brain health just as important as physical health

The Y rolls out new health program targeting diabetes

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Tau release from healthy neurons can be regulated by neuronal activity

Protein-restricted diet supplemented with IGF-I may protect from Alzheimer's

Targacept reports net loss of $15.9 million for fourth quarter 2012

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

Antibody therapeutics targeting GPCRs to be developed by alliance between MorphoSys and Heptares

Study finds abnormal production of C9RANT in patients with ALS, frontotemporal dementia

Four-month instructional dance program can improve health of Latino seniors

Experts discuss hottest topics in Alzheimer's brain imaging at 7th HAI conference

FDA issues draft guidance on developing new treatments for Alzheimer's

Report: The number of Americans with Alzheimer's disease will almost triple by 2050

Roundup: Assisted suicide legalization urged; Abortion bill tensions in Wash., Ore.; Budget squeezes in Ga., Conn.

Drugs that target retromer pathway could help prevent or treat Parkinson's

Alzheimer's appears to be on the rise

Nerve stimulator may be new option for migraine sufferers

Society of Toxicology's 52nd Annual Meeting to be held from Mar. 10-16 in San Antonio

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