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Customized gene chip will offer clues to prognosis in cases of neuroblastoma

Genetics researchers have developed a customized gene chip to rapidly scan tumor samples for specific DNA changes that offer clues to prognosis in cases of neuroblastoma, a common form of children's cancer.

2 Aug 2005

Discovery may lead to new therapies for leukemia

Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.

2 Aug 2005

Study finds risk of death increases with peritoneal dialysis over hemodialysis

Researchers at Johns Hopkins have found that in people with end-stage kidney disease (ESRD), choosing peritoneal dialysis over hemodialysis increases their risk of dying by 50 percent.

2 Aug 2005

Elderly need to make sure they get enough vitamin B12

These days, most health warnings about vitamins focus on the danger of overdose. For vitamin B12, though, it's more likely that people are getting too little. In fact, B12 deficiency is the most common nutritional deficiency in the developing world and possibly in the United States as well, reports the August issue of the Harvard Health Letter.

2 Aug 2005

Surgical myectomy gives fresh start to patients with hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM), an abnormal thickening of the heart, affects more than 500,000 Americans, making it more common than better-known conditions such as Crohn's disease, Multiple Sclerosis and Anorexia Nervosa.

2 Aug 2005

Arf gene prevents excessive growth of blood vessels in the developing eye

A gene better known for its role in preventing cancer also plays a key role in the developing embryo, where the gene prevents excessive growth of blood vessels, according to investigators at St. Jude Children's Research Hospital.

2 Aug 2005

Researchers characterize the proteome of the human cornea

In doing so, they have identified 141 distinct proteins, 99 of which had not been previously recognized in mammalian corneas. The details of their findings appear in the August/September issue of Molecular and Cellular Proteomics, an American Society for Biochemistry and Molecular Biology journal.

1 Aug 2005

Visceral obesity may be an important risk factor for insulin resistance syndrome in children

Waist circumference is associated with insulin resistance in children and may offer a simple way to identify children with risk factors for cardiovascular disease and type 2 diabetes, according to a study in the August issue of Archives of Pediatrics & Adolescent Medicine.

1 Aug 2005

Researchers unravel control of growing blood vessels

Researchers at UT Southwestern Medical Center have discovered a basic mechanism by which smooth muscle cells that line the blood vessels can grow - sometimes abnormally - suggesting methods of treatment for various coronary diseases.

1 Aug 2005

New recommendations can help medical arms of the military meet their mission

As reported last December in the New England Journal of Medicine, the U.S. military's on-the-ground surgical strategy now aims at "damage control, not definitive repair, unless it can be done quickly."

1 Aug 2005

Dairy foods may actually help dieters keep the muscle and lose even more fat

Most people don't realize when a person loses weight, they lose fat and muscle, but new research indicates dairy foods may actually help dieters keep the muscle and lose even more fat.

1 Aug 2005

Heparinase I is not a suitable replacement for protamine

The results of an international clinical trial led by Duke University Medical Center researchers has shown that a new drug is not a suitable replacement for protamine, a drug that has been used for more than 40 years after coronary artery bypass surgery to return thinned blood to its normal state.

1 Aug 2005

Pseudomonas aeruginosa has broken the immune system's code

The human opportunistic pathogen, Pseudomonas aeruginosa, has broken the immune system's code, report researchers from the University of Chicago, enabling the bacteria to recognize when its host is most vulnerable and to launch an attack before the weakened host can muster its defenses.

1 Aug 2005

Study findings will help early detection and treatment of hyperglycemic diabetes

In a groundbreaking population-based study, researchers in Mayo Clinic Cancer Center found that new onset of hyperglycemic diabetes in adults age 50 or older may be a signal of underlying pancreatic cancer.

1 Aug 2005

Possible early warning system for heart problems

By using sound waves Mayo Clinic researchers have described subtle changes in the motion of the heart that are measurable by ultrasound and may improve understanding of heart function, and possibly be a noninvasive aid in predicting impending heart damage including heart attacks.

31 Jul 2005

Combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission

Two new studies support the hypothesis that combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission through breastfeeding, findings that could have significant implications in the developing world.

29 Jul 2005