Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Potential ways for doctors to improve hormone receptor-positive breast cancer treatment

American and Spanish researchers have found potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests, as they report at the 4th IMPAKT Breast Cancer Conference.

4 May 2012

New genetic pathway influences spread of cancer cells

In a new study from Lawson Health Research Institute, Dr. Joseph Torchia has identified a new genetic pathway influencing the spread of cancer cells. The discovery of this mechanism could lead to new avenues for treatment.

4 May 2012

Competition to celebrate art in medicine

It turns out beauty really is skin deep. A hair follicle or skin specimen that doesn't look like much of anything to the naked eye can become a complex, colorful work of art under a microscope. Mayo Clinic dermatologists struck by the beauty they see in the cellular have started a competition to celebrate art in medicine. The winning entries appear in the May issue of the Journal of Cutaneous Pathology.

3 May 2012

Cone beam CT superior to mutidetector CT for detecting superior semicircular canal dehiscence

Cone beam CT is superior to mutidetector CT for detecting superior semicircular canal dehiscence or the so called third window (a small hole in the bony wall of the inner ear bone that can cause dizziness and hearing loss) and it uses half the radiation dose, a new study shows.

3 May 2012

New clues about why immune system fails to kill tumors in mice

A pioneering approach to imaging breast cancer in mice has revealed new clues about why the human immune system often fails to attack tumors and keep cancer in check. This observation, by scientists at the University of California, San Francisco (UCSF), may help to reveal new approaches to cancer immunotherapy.

3 May 2012

Probiodrug AG, collaborators explain interplay of key suspects in Alzheimer’s

Probiodrug AG (Probiodrug), a biotech company developing products for the treatment of neurodegenerative and inflammatory diseases with a particular focus on Alzheimer's disease (AD), today announced its scientists and academics collaborators published seminal findings on the role of pyroglu Aβ in AD pathology in the May 2, 2012 online edition of the journal Nature (DOI: 10.1038/nature11060). The new findings add to the growing body of evidence that pyroglu Aβ plays a crucial role in the initiation of AD. In addition, the research results further elucidate the mechanism by which pyroglu Aβ triggers neuronal toxicity.

3 May 2012

Grape-derived compound may prevent neurodegenerative disorders involving tau neuropathology

Researchers at Mount Sinai School of Medicine have gained insight into the mechanism by which a pathological brain protein called tau contributes to the progression of Alzheimer's disease (AD) and other neurodegenerative disorders. This finding, published in the most recent issue of the Journal of Biological Chemistry, may provide the basis for future investigations on how to prevent tau from damaging brain circuits involved in cognitive function.

2 May 2012

Antibody that neutralizes enzyme Kallikrein 6 staves off MS

Researchers studying multiple sclerosis(MS) have long been looking for the specific molecules in the body that cause lesions in myelin, the fatty, insulating cells that sheathe the nerves.

30 Apr 2012

Study reveals direct correlation between negative thinking about pain and poor sleep

Chronic pain sufferers who learn to dwell less on their ailments may sleep better and experience less day-to-day pain, according to results of research conducted on 214 people with chronic face and jaw pain.

27 Apr 2012

Change in attitude may ease chronic pain by aiding sleep: Study

26 Apr 2012

A melanoma cloaking protein

Johns Hopkins and Yale scientists have found that melanoma cells use a cloaking protein to hide from immune cells poised to attack the cancer. Nearly 40 percent of their sampling of melanoma tissues contained the B7-H1 protein, also called PD-L1, and scientists say it could be used as a target for new therapies.

26 Apr 2012

AAA to gather for anatomy meeting in conjunction with Experimental Biology 2012

The American Association of Anatomists will gather this week for its annual meeting in conjunction with the Experimental Biology 2012 conference, which will draw more than 14,000 scientists from industry, government and academia. Below are some programming highlights for the anatomy meeting. All presentations will be made at the San Diego Convention Center.

26 Apr 2012

U of A develops new technology that enables personalized medicine

You wouldn't know it from appearances, but a metal cube the size of a toaster, created at the University of Alberta, is capable of performing the same genetic tests as most fully equipped modern laboratories-and in a fraction of the time.

26 Apr 2012

IMPAKT 2012 breast cancer conference to focus on four major areas

"Basic science and clinical medicine move at different pace because they follow different paths. Both however aim at improving strategies to manage cancer patients. We need to efficiently translate the good things from basic science and efficiently implement them in the clinic."

26 Apr 2012

Melanomas express B7-H1 protein to hide from T-cells

26 Apr 2012

U-M’s second human embryonic stem cell line now available for federally-funded research

The University of Michigan's second human embryonic stem cell line has just been placed on the U.S. National Institutes of Health's registry, making the cells available for federally-funded research. It is the second of the stem cell lines derived at U-M to be placed on the registry.

26 Apr 2012

Louisiana Tech professor, students present at 2012 Experimental Biology meeting

Several graduate and Ph.D. students at Louisiana Tech University, and Dr. David Mills, professor of biological sciences and faculty in Tech's Center for Biomedical Engineering and Rehabilitation Science, are participating in poster and platform presentations at the 2012 Experimental Biology meeting, this week in San Diego, California.

26 Apr 2012

Physical activity reduces oxidative stress in people with SCT

Sickle cell disease (SCD), an inherited condition that causes red blood cells to sometimes deform into a crescent shape, affects an estimated 100,000 Americans, typically those of African descent. However, far more have sickle cell trait (SCT), caused when individuals carry just a single copy of the disease-causing mutation in their genes.

26 Apr 2012

PLUS Diagnostics, MDxHealth partner to co-promote ConfirmMDx for Prostate Cancer

MDxHealth SA, a leading molecular diagnostic company that develops and commercializes epigenetic tests to support cancer treatment, and PLUS Diagnostics today announced that they have entered into an agreement to co-promote MDxHealth's ConfirmMDx for Prostate Cancer test in the United States.

26 Apr 2012

Custom-made mouthpieces can decrease levels of serum cortisol following exercise

Mouthguards are used by almost everyone participating in sports. These devices, typically purchased over-the-counter and used on the upper teeth, are designed to protect against broken teeth and an injured tongue. Recently, researchers in South Carolina found that a customized device which rests on the lower jaw can decrease levels of serum cortisol following exercise.

26 Apr 2012

Pathology News and Research

Further Reading

Potential ways for doctors to improve hormone receptor-positive breast cancer treatment

New genetic pathway influences spread of cancer cells

Competition to celebrate art in medicine

Cone beam CT superior to mutidetector CT for detecting superior semicircular canal dehiscence

New clues about why immune system fails to kill tumors in mice

Probiodrug AG, collaborators explain interplay of key suspects in Alzheimer’s

Grape-derived compound may prevent neurodegenerative disorders involving tau neuropathology

Antibody that neutralizes enzyme Kallikrein 6 staves off MS

Study reveals direct correlation between negative thinking about pain and poor sleep

Change in attitude may ease chronic pain by aiding sleep: Study

A melanoma cloaking protein

AAA to gather for anatomy meeting in conjunction with Experimental Biology 2012

U of A develops new technology that enables personalized medicine

IMPAKT 2012 breast cancer conference to focus on four major areas

Melanomas express B7-H1 protein to hide from T-cells

U-M’s second human embryonic stem cell line now available for federally-funded research

Louisiana Tech professor, students present at 2012 Experimental Biology meeting

Physical activity reduces oxidative stress in people with SCT

PLUS Diagnostics, MDxHealth partner to co-promote ConfirmMDx for Prostate Cancer

Custom-made mouthpieces can decrease levels of serum cortisol following exercise

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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