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Neutrophils dictate whether our immune system will permit or prevent bacterial infections

New research on a bacterium that can survive encounters with specific immune system cells has strengthened scientists' belief that these plentiful white blood cells, known as neutrophils, dictate whether our immune system will permit or prevent bacterial infections.

5 May 2005

Cancer hijacks normal wound-healing processes

Scientists have known for the last decade that a link exists between wound healing and cancer. For instance, in a 1994 experiment at the Lawrence Berkeley National Laboratory, chickens infected with a cancer virus developed tumors in areas of their body that had undergone wounding or scarring, while no tumors developed in infected areas that had not suffered wounding.

5 May 2005

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Two infant boys whose bodies were overloaded with excess fluid have led UCSF pediatricians to the discovery of a new genetic disease. In the process, they have discovered a rare type of mutation where different substitutions in a single amino acid cause two different, opposite genetic disorders.

4 May 2005

People may consume more calories after exercising in cold water

Exercise in cold water instead of warm water may increase people's appetites, making it harder for them to lose extra pounds, a University of Florida study finds.

4 May 2005

Internet may help prevent blindness in Medicaid patients with diabetes

A Wake Forest University Baptist Medical Center team is launching a high-tech study to determine if early screening using a special camera and images transmitted over the Internet can prevent blindness in Medicaid patients with diabetes.

4 May 2005

Specific variants of genes predict bleeding after heart surgery

Duke University Medical Center researchers have found that the presence of specific variants of genes that control clotting and the contractility, or "tone," of blood vessels can double the ability of physicians to predict those heart surgery patients at greatest risk of bleeding after surgery.

4 May 2005

Scalpel-free surgery could reduce risk of HIV and Hepatitis exposure for health care workers in city hospitals

While the incidence of disease from HIV and hepatitis is increasing in the United States, little is known about their prevalence in patients undergoing surgery. Now, researchers have shown that nearly 40 percent of surgeries at The Johns Hopkins Hospital occur in patients who tested positive for a bloodborne germ.

4 May 2005

Glucose byproduct prevents brain damage after diabetic coma

A natural, non-toxic byproduct of glucose may prevent brain cell death and cognitive impairment in diabetics following an episode of severely low blood sugar, according to researchers at the San Francisco VA Medical Center (SFVAMC).

4 May 2005

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur other, slower-responding immune cells to go to work.

4 May 2005

Heart failure patients do better when treated according to guidelines, but too many doctors still fail to prescribe the best treatments

Heart failure patients who are treated in accordance with established European guidelines do better than patients who are not, yet many doctors are still not adhering to the guidelines, according to pioneering research published in Europe’s leading cardiology journal, the European Heart Journal.

4 May 2005

Abnormal heart scans predict higher risks for African-Americans and Hispanics

SPECT imaging scans show that abnormalities in blood flow to the muscle of the heart indicate higher cardiovascular disease risk in African-Americans and Hispanics than similar abnormalities in white patients, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Research suggests potential new strategies for fighting age-related vascular disease

Declining function of cells that help repair the inner lining of blood vessels, known as endothelial progenitor cells, rather than a dwindling supply of the cells, may underlie the increased risk of atherosclerosis and other vascular diseases as people grow older, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Diabetes appears to rob women of usual advantage in heart disease risk

For men, a heart attack increases the risk of dying from coronary heart disease more than diabetes does, but for women, diabetes is sometimes the greater threat, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Diabetes researchers look at pizza to find slow and steady insulin delivery wins the race

With its doughy, carbohydrate-dense crust and high fat content, pizza can wreak havoc in people with diabetes. A Penn State Diabetes Center study suggests a slow and steady insulin-dosing pattern may best combat the glucose-raising effects of that common favorite food.

3 May 2005

Researchers have successfully induced adult heart-muscle cells to divide and multiply

In the best documented effort to date, researchers from the Howard Hughes Medical Institute at Children's Hospital Boston and Harvard Medical School have successfully induced adult heart-muscle cells to divide and multiply.

3 May 2005

Burden of cardiovascular disease will shift to the developing world

In a paper published this week in the premier open-access global health journal PLoS Medicine, Majid Ezzati and colleagues from Harvard School of Public Health conclude that a large proportion of the world's population who live in low-income and middle-income countries should be the focus for intervention against risk factors for cardiovascular disease because major cardiovascular risk factors will increasingly be concentrated in these populations.

3 May 2005

If you eat too much fat, it can go straight to your liver and damage it

In obese people with nonalcoholic fatty liver disease (NAFLD), fat from the diet ends up "stuck" in the liver, where it doesn't belong. It was known that the livers of NAFLD patients accumulated fat, but its origin was unknown.

3 May 2005

Critical lock and key mechanism found for the assembly of tumor blood vessels

A critical lock and key mechanism that allows the final step in the completion of new blood vessel formation has been identified by a University of California, San Diego (UCSD) School of Medicine team in research that promises to lead to a new way to halt tumor growth by cutting off the tumor blood supply.

3 May 2005

Scientists dramatically slow organ transplant rejection

That's the promising implication of an animal study carried out by researchers at the University of Alabama at Birmingham (UAB) and the University of Florida (UF) published in today's (May 2) issue of Proceedings of the National Academy of Sciences.

3 May 2005

College freshies show weaker immune responses

Being a college freshie may have more ramifications than being lonely and missing Mum's cooking, according to a new study at Carnegie Mellon University in Pittsburgh which shows that first-year students had a weaker immune response to the flu shot than did other students, and confirms suspicions that going to college challenges both mind and body.

2 May 2005