Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Brain freeze may share common mechanism with other types of headaches

'Brain freeze' is a nearly universal experience—almost everyone has felt the near-instantaneous headache brought on by a bite of ice cream or slurp of ice-cold soda on the upper palate. However, scientists are still at a loss to explain this phenomenon. Since migraine sufferers are more likely to experience brain freeze than people who don't have this often-debilitating condition, brain freeze may share a common mechanism with other types of headaches, including those brought on by the trauma of blast-related combat injuries in soldiers.

23 Apr 2012

Estrone provides anti-inflammatory and antioxidant capabilities after TBI

With more than 1.7 million people sustaining a traumatic brain injury each year, the need to identify processes to limit inflammation and subsequent damage is critical. Approximately 275,000 people are hospitalized annually with traumatic brain injury, leaving 85,000 with long-term disabilities and taking the lives of more than 50,000. More than 5 million people live with disabilities caused by traumatic brain injuries, often the result of car accidents and falls. Direct and indirect costs exceed $75 billion.

23 Apr 2012

HBO2 therapy can reduce neuropathic pain

Chronic pain affects about 76 million people in the U.S. and carries an economic burden of nearly $100 billion annually. The most frequently used medications, narcotic and non-narcotic analgesic drugs (e.g., morphine, ibuprofen, etc.), do not provide complete or sustained relief of chronic pain. Scientists are currently seeking alternative solutions for chronic pain management.

23 Apr 2012

Researchers identify molecular pathway that controls retention, release of the brain's stem cells

Researchers at Columbia University Medical Center (CUMC) have identified a molecular pathway that controls the retention and release of the brain's stem cells.

23 Apr 2012

Health Discovery launches MelApp for melanoma risk assessment

Health Discovery Corporation, the molecular diagnostics company that launched MelApp, the first SVM-based image analysis iPhone app for melanoma risk assessment is featured in this month's Men's Health Magazine.

21 Apr 2012

Penn researchers continue efforts to differentiate Alzheimer's from FTLD

Teasing out the exact type or types of dementia someone suffers from is no easy task; neurodegenerative brain diseases share common pathology and often co-occur. Researchers from the Perelman School of Medicine at the University of Pennsylvania are continuing efforts to differentiate diseases, such as Alzheimer's disease (AD) from frontotemporal lobar degeneration (FTLD), as FTLD is often clinically difficult to distinguish from atypical presentations of AD.

21 Apr 2012

Possibility to render cancer tumours harmless without affecting other cells

New research findings show how it may be possible to render cancer tumours harmless without affecting the other cells and tissues in the body. The findings apply to cancers including breast, lung and bowel cancer. The study was carried out at Lund University in Sweden.

20 Apr 2012

Study shows efficacy of Infant Behavior, Cry and Sleep Clinic's model of integrated care

Having a new baby brings much joy to a new family. But for a family whose baby cries for hours on end, fusses through feedings, or has difficulty sleeping, the joy may be overshadowed by feelings of helplessness and frustration. The treatment of that infant - and that family - will impact the parent-child relationship for years to come.

20 Apr 2012

HIAE, MD Anderson partner to develop oncology program

The University of Texas MD Anderson Cancer Center today announced an agreement with Hospital Israelita Albert Einstein (HIAE) in São Paulo, Brazil, creating an alliance to develop a comprehensive, multidisciplinary oncology program at the hospital.

20 Apr 2012

Myomatrix 2012 conference to take place from April 22-24

The nation's leading scientists and clinicians exploring treatment breakthroughs for congenital muscular dystrophy will convene April 22-24 on the campus of the University of Nevada, Reno, where research by Dean Burkin has led to a potential therapy.

19 Apr 2012

BCCA, UBC scientists identify new breast cancer genes

Scientists at the BC Cancer Agency and University of British Columbia have identified new breast cancer genes that could change the way the disease is diagnosed and form the basis of next-generation treatments.

19 Apr 2012

New study recommends intraoperative histological evaluation for Hirschsprung disease treatment

Hirschsprung disease occurs when nerve cells in the colon do not develop normally before birth and the bowel is unable to move its contents along. Severe bowel obstruction and even perforation can then occur. The condition is usually diagnosed within the first months of life, but can be found in older children as well.

18 Apr 2012

Study demonstrates how Parkinson's disease protein can spread in patient's brain

Last year, researchers from the Perelman School of Medicine at the University of Pennsylvania found that small amounts of a misfolded brain protein can be taken up by healthy neurons, replicating within them to cause neurodegeneration. The protein, alpha-synuclein (a-syn), is commonly found in the brain, but forms characteristic clumps called Lewy bodies, in neurons of patients with Parkinson's disease (PD) and other neurodegenerative disorders.

18 Apr 2012

Genetically modified mouse mimics key features of Charcot-Marie-Tooth disease

A team of scientists from the University of Missouri created a genetically modified mouse that mimics key features of Charcot-Marie-Tooth disease, an inherited neuromuscular disease affecting approximately 150,000 people in the United States.

18 Apr 2012

Frequent but moderate consumption of alcohol before and after heart attack may improve health outcomes

The Health Professionals Follow-up Study (HPFS) is a prospective cohort study of 51,529 US male health professionals. During the follow up of these men between 1986 to 2006, published in the European Heart Journal, 1,818 men were confirmed with incident non-fatal myocardial infarction (MI) - a non fatal heart attack.

18 Apr 2012

Innovation in healthcare without borders: An invaluable contribution of diagnostics

For the third year in a row, the European Diagnostic Manufacturers Association (EDMA) has been one of the strategic partners of the European Commission in organising the Innovation in Healthcare without Borders conference.

17 Apr 2012

Novel system for 3D reconstruction and examination of tissues at microscopic resolution

Researchers have developed a novel, easy-to-use system for three-dimensional (3D) reconstruction and examination of tissues at microscopic resolution, with the potential to significantly enhance the study of normal and disease processes, particularly those involving structural changes. The new approach, using conventional histopathological methods, is described in the May issue of The American Journal of Pathology.

17 Apr 2012

PDAD patients have much denser accumulations of striatal plaques in the brain

Dementia is a frequent complication of Parkinson's disease (PD), but it is clinically impossible to distinguish PD dementia (PDD), which develops from the progression of the Lewy body pathology that underlies PD, from PD with coexistent Alzheimer's disease.

17 Apr 2012

Two related enzymes play a key role in development of T-ALL

Columbia University Medical Center (CUMC) scientists have demonstrated that two related enzymes - phosphoinositide-3 kinase (PI3K) gamma and delta - play a key role in the development of T-cell acute lymphoblastic leukemia (T-ALL), a highly aggressive childhood leukemia that is difficult to treat.

17 Apr 2012

Paper points out decision-making capacity of patients with dementia

Luis Carlos álvaro, a clinical neurologist at the Hospital of Basurto (Bilbao) and lecturer at the University of the Basque Country (UPV/EHU), has had an article published on the capacity of patients with dementia to make decisions. It is entitled Competencia: conceptos generales y aplicación en la demencia (Competence: general concepts and application in dementia), and has been published in the journal Neurología.

17 Apr 2012

Pathology News and Research

Further Reading

Brain freeze may share common mechanism with other types of headaches

Estrone provides anti-inflammatory and antioxidant capabilities after TBI

HBO2 therapy can reduce neuropathic pain

Researchers identify molecular pathway that controls retention, release of the brain's stem cells

Health Discovery launches MelApp for melanoma risk assessment

Penn researchers continue efforts to differentiate Alzheimer's from FTLD

Possibility to render cancer tumours harmless without affecting other cells

Study shows efficacy of Infant Behavior, Cry and Sleep Clinic's model of integrated care

HIAE, MD Anderson partner to develop oncology program

Myomatrix 2012 conference to take place from April 22-24

BCCA, UBC scientists identify new breast cancer genes

New study recommends intraoperative histological evaluation for Hirschsprung disease treatment

Study demonstrates how Parkinson's disease protein can spread in patient's brain

Genetically modified mouse mimics key features of Charcot-Marie-Tooth disease

Frequent but moderate consumption of alcohol before and after heart attack may improve health outcomes

Innovation in healthcare without borders: An invaluable contribution of diagnostics

Novel system for 3D reconstruction and examination of tissues at microscopic resolution

PDAD patients have much denser accumulations of striatal plaques in the brain

Two related enzymes play a key role in development of T-ALL

Paper points out decision-making capacity of patients with dementia

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